Emily Farina, PhD
Assistant Professor in PsychiatryCards
About
Research
Publications
2026
Clinical High Risk for Psychosis: Policy, Programs, and Practice
Farina, E.A., Saxena, A., & Montague, E. (in press). Clinical High Risk for Psychosis: Policy, Programs, and Practice. In T. J. McMahon (Ed.), Child well-being and child development: A systems perspective on science, policy, and practice (Chapter 13). Springer.Chapters747. Reproductive Hormone Disruption and Psychosis Risk in Midlife Women: Evidence From Surgical Models and Lifetime Estrogen Exposure
Gibbs-Dean T, Dandawate A, Patel P, Kelley M, Ntongo B, Farina E, Woods S, Pal L, Powers A. 747. Reproductive Hormone Disruption and Psychosis Risk in Midlife Women: Evidence From Surgical Models and Lifetime Estrogen Exposure. Biological Psychiatry 2026, 99: s418. DOI: 10.1016/j.biopsych.2026.03.981.Peer-Reviewed Original ResearchStepped care for young people at clinical high risk for psychosis: a real-world study
Broekhuijse A, Saxena A, Walsh B, Mourgues-Codern C, Mukhtar H, Howard S, Woods SW, Powers AR, Farina EA. Stepped care for young people at clinical high risk for psychosis: a real-world study. 2026 DOI: 10.64898/2026.02.05.26345683.Peer-Reviewed Original Research In Press
2025
Shift in sex and age of individuals at a clinical high risk (CHR) for psychosis: relation to differences in recruitment methods and effect on sample characteristics
Farina E, Mourgues-Codern C, Stimler K, Kenney J, Saxena A, Mukhtar H, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Ellman L, Gold J, Keshavan M, Mathalon D, Mittal V, Perkins D, Schiffman J, Silverstein S, Strauss G, Stone W, Walker E, Waltz J, Corlett P, Powers A, Woods S. Shift in sex and age of individuals at a clinical high risk (CHR) for psychosis: relation to differences in recruitment methods and effect on sample characteristics. Schizophrenia 2025, 11: 123. PMID: 41053030, PMCID: PMC12501016, DOI: 10.1038/s41537-025-00663-5.Peer-Reviewed Original ResearchClinical high riskClinical high-risk samplesNorth American Prodrome Longitudinal StudyOvert psychotic disordersSample characteristicsSample of individualsNegative symptomsPsychotic disordersPsychosis riskSelf-referralRecruitment sourcesBetween-study differencesComputerized assessmentHierarchical regressionPsychosisRecruitment source effectsClinical implicationsLongitudinal studyGeneral symptomsDemographic differencesClinical profileSymptomsParticipantsClinical heterogeneitySexPrediction of antipsychotic medication inception in antipsychotic-naive youth at clinical high risk for psychosis
Mukhtar H, Zhou D, Farina E, Saxena A, Cahill J, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshwan M, Mathalon D, Perkins D, Stone W, Cho Y, Powers A, Walker E, Woods S. Prediction of antipsychotic medication inception in antipsychotic-naive youth at clinical high risk for psychosis. Psychological Medicine 2025, 55: e241. PMID: 40842369, PMCID: PMC12404330, DOI: 10.1017/s0033291725101372.Peer-Reviewed Original ResearchClinical high riskCHR-PLifetime historyAugmentation of antidepressant treatmentComorbid major depressionAP useAntidepressant treatmentPositive symptomsMajor depressionAP medicationNAPLS-2Independent predictorsCHR-P.High riskBaseline clinical variablesPsychosisBaseline predictorsClinical variablesParticipantsBaseline characteristicsUnivariate analysisLogistic regression modelsObservational cohortMultivariate analysisAP initiationEmergence and Dynamics of Delusions and Hallucinations Across Stages in Early Psychosis
Mourgues-Codern C, Benrimoh D, Gandhi J, Farina E, Vin R, Zamorano T, Parekh D, Malla A, Joober R, Lepage M, Iyer S, Addington J, Bearden C, Cadenhead K, Cornblatt B, Keshavan M, Stone W, Mathalon D, Perkins D, Walker E, Cannon T, Woods S, Shah J, Powers A. Emergence and Dynamics of Delusions and Hallucinations Across Stages in Early Psychosis. Biological Psychiatry 2025, 98: 679-688. PMID: 40020853, PMCID: PMC12353309, DOI: 10.1016/j.biopsych.2025.02.891.Peer-Reviewed Original ResearchFirst-episode psychosis patientsSymptom patternsNorth American Prodrome Longitudinal StudyPositive symptoms of psychosisSymptoms of psychosisCHR-P samplesEarly intervention programsPositive symptomsDelusional ideationPsychosis patientsEarly psychosisCHR-PNeural mechanismsDelusionsHallucination onsetHallucinationsPsychosisBaseline assessmentLongitudinal studyIntervention programsSymptomsTime courseParticipantsIdeationOnsetBaseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program
Addington J, Liu L, Chu M, Jungert K, Penzel N, Pasternak O, Farina E, Carrion R, Corcoran C, Mittal V, Strauss G, Yung A, Alameda L, Arango C, Borders O, Bouix S, Breitborde N, Broome M, Cadenhead K, Castillo-Passi R, Chen E, Choi J, Coleman M, Conus P, Diaz-Caneja C, Ellman L, Poli P, Gaspar P, Gerber C, Glenthøj L, Horton L, Hui C, Kambeitz J, Kambeitz-Ilankovic L, Kapur T, Kelly S, Kerr M, Keshavan M, Kim M, Kim S, Koutsouleris N, Kwon J, Langbein K, Lewandowski K, Mamah D, Marcy P, Mathalon D, Mourgues C, Nordentoft M, Nunez A, Pearlson G, Perez J, Perkins D, Powers A, Rogers J, Sabb F, Schiffman J, Seitz-Holland J, Shah J, Silverstein S, Smesny S, Stone W, Thompson J, Upthegrove R, Verma S, Wang J, Wolf D, Zhang T, Addamo L, Buccilli K, Dwyer D, Todd S, Cho Y, Fontenau C, Tamayo Z, Bearden C, Kane J, McGorry P, Kahn R, Shenton M, Woods S, Barnaby A, Calkins M. Baseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program. Schizophrenia Bulletin Open 2025, 6: sgaf012. PMID: 40861307, PMCID: PMC12377803, DOI: 10.1093/schizbullopen/sgaf012.Peer-Reviewed Original ResearchClinical high riskCommunity controlsClinical high-risk individualsClinical high-risk participantsClinical high-risk criteriaClinical high-risk populationsPsychosis-Risk SyndromesClinical measuresNegative symptomsPositive symptomsPsychosis-riskPsychotic symptomsDSM-5Characterization of participantsSchizophrenia ProgramClinical variablesSuicidal ideationDiagnostic criteriaSubstance useSeverity ratingsComprehensive assessmentStructured interviewsPsychosisPreliminary natureAt-riskSample Ascertainment and Recruitment Sources in the Accelerating Medicines Partnership Schizophrenia Program
Addington J, Shalev A, Liu L, Jahraus C, Chu M, Farina E, Poli P, Marcy P, Nunez A, Calkins M, Alameda L, Arango C, Borders O, Bouix S, Breitborde N, Broome M, Cadenhead K, Carrion R, Castillo-Passi R, Chen E, Choi J, Coleman M, Conus P, Corcoran C, Diaz-Caneja C, Ellman L, Gaspar P, Gerber C, Glenthøj L, Horton L, Hui C, Kambeitz J, Kambeitz-Ilankovic L, Kapur T, Kelly S, Kerr M, Keshavan M, Kim M, Kim S, Koutsouleris N, Kwon J, Langbein K, Lewandowski K, Mamah D, Mathalon D, Mittal V, Mourgues C, Nordentoft M, Pasternak O, Pearlson G, Penzel N, Perez J, Perkins D, Powers A, Rogers J, Sabb F, Schiffman J, Seitz-Holland J, Shah J, Silverstein S, Smesny S, Stone W, Strauss G, Thompson J, Upthegrove R, Verma S, Wang J, Wolf D, Yung A, Zhang T, Addamo L, Buccilli K, Todd S, Dwyer D, Bearden C, Kane J, McGorry P, Kahn R, Shenton M, Woods S, Barnaby A. Sample Ascertainment and Recruitment Sources in the Accelerating Medicines Partnership Schizophrenia Program. Schizophrenia Bulletin Open 2025, 6: sgaf013. PMID: 40861306, PMCID: PMC12377801, DOI: 10.1093/schizbullopen/sgaf013.Peer-Reviewed Original ResearchClinical high riskSelf-referralRecruitment sourcesCommunity controlsAdult community mental health servicesCommunity mental health servicesMental health servicesSocial functioningHelp-seeking behaviorSelf-referred individualsLevel of functionHealthcare providersHealth servicesSample ascertainmentClinical high-risk participantsClinical high-risk criteriaClinical high-risk researchComprehensive assessmentSchizophrenia ProgramCommunity agenciesPsychiatric hospitalSevere APAt-riskOutreach effortsRecruitment groupSocial functioning and frontal alpha asymmetry in schizophrenia
Farina E, Assaf M, Corbera S, Choi J, Yantz C, Chen C. Social functioning and frontal alpha asymmetry in schizophrenia. Journal Of Psychiatric Research 2025, 182: 74-82. PMID: 39799666, PMCID: PMC11830537, DOI: 10.1016/j.jpsychires.2025.01.006.Peer-Reviewed Original ResearchConceptsFrontal alpha asymmetryAutism spectrum disorderReduced social functioningSocial functioningNeurophysiological markersAlpha asymmetryPsychiatric disordersAtypical social behaviorUnique to schizophreniaSelf-report measuresHealthy controlsResting-state electroencephalogramClinical InterviewPsychiatric diagnosisSchizophreniaSpectrum disorderDiagnostic groupsReduced motivationSocial behaviorDisordersEmotional tendencyAnalysis of varianceClinical manifestationsElectroencephalogramAutism
2024
A Computational Account of the Development and Evolution of Psychotic Symptoms
Powers A, Angelos P, Bond A, Farina E, Fredericks C, Gandhi J, Greenwald M, Hernandez-Busot G, Hosein G, Kelley M, Mourgues C, Palmer W, Rodriguez-Sanchez J, Seabury R, Toribio S, Vin R, Weleff J, Woods S, Benrimoh D. A Computational Account of the Development and Evolution of Psychotic Symptoms. Biological Psychiatry 2024, 97: 117-127. PMID: 39260466, PMCID: PMC11634669, DOI: 10.1016/j.biopsych.2024.08.026.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPsychotic symptomsSymptom formationEmergence of psychotic symptomsConversion to psychosisPrediction error signalsIncoming sensory informationHallucination severityDiminished signal-to-noise ratioComputational accountPsychiatric interventionNeural systemsHallucinationsIncreasing convictionOver-reliancePsychosisSensory informationLongitudinal developmentSymptomsBelief formation
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