The Impact of Radiation Energy on Dose Homogeneity and Organ Dose in the Gttingen Minipig Total-Body Irradiation Model
Poirier Y, Becker S, Decesaris C, Culberson W, Draeger E, Gerry AJ, Johnstone CD, Gibbs A, Vujaskovic Z, Jackson IL. The Impact of Radiation Energy on Dose Homogeneity and Organ Dose in the Gttingen Minipig Total-Body Irradiation Model. Radiation Research 2020, 194: 544-556. PMID: 33045066, DOI: 10.1667/rade-20-00135.1.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAbsorption, RadiationAnimalsBody SizeBody WeightCobalt RadioisotopesDose-Response Relationship, RadiationGamma RaysMaleModels, AnimalOrgan SpecificityParticle AcceleratorsPelvisPhotonsProne PositionRadiation DosageRadiation ToleranceRadioisotope TeletherapyRadiotherapy Planning, Computer-AssistedRadiotherapy, High-EnergyShoulderSwineSwine, MiniatureTomography, X-Ray ComputedWhole-Body IrradiationConceptsTotal body irradiationDose-volume histogramsGöttingen minipigsThoracic organsMedical countermeasuresRadiation dose-response relationshipDose-response relationshipNormal tissue damageDose distributionExperienced radiation oncologistsAdditional confounding factorsTBI modelPelvic organsHigh doseIndividual organsAnimal modelsAverage doseConfounding factorsRadiation oncologistsTissue damageLess doseOrgan doseAverage dosesDose homogeneityDose