Hematological Effects of Non-Homogenous Ionizing Radiation Exposure in a Non-Human Primate Model
Jackson IL, Gibbs A, Poirier Y, Wathen L, Eley J, Draeger E, Gopalakrishnan M, Benjamin B, Vujaskovic Z. Hematological Effects of Non-Homogenous Ionizing Radiation Exposure in a Non-Human Primate Model. Radiation Research 2019, 191: 428-438. PMID: 30870098, DOI: 10.1667/rr15280.1.Peer-Reviewed Original ResearchConceptsLower half-body irradiationUpper half body irradiationHalf-body irradiationTotal body irradiationDose-volume effectsNon-human primatesBM toxicityRadiation exposureBone marrowClinical signs/symptomsRadiation dose-volume effectsNon-human primate modelHigh-grade feverSigns/symptomsBone marrow toxicityPeripheral blood samplesAcute radiation syndromeIonizing Radiation ExposureBlood-forming organsSevere neutropeniaRespiratory distressHematologic changesMarrow toxicityBM damagePrimate model