Use of CT simulation and 3-D radiation therapy treatment planning system to develop and validate a total-body irradiation technique for the New Zealand White rabbit
Poirier Y, Prado C, Prado K, Draeger E, Jackson IL, Vujaskovic Z. Use of CT simulation and 3-D radiation therapy treatment planning system to develop and validate a total-body irradiation technique for the New Zealand White rabbit. International Journal Of Radiation Biology 2020, 97: s10-s18. PMID: 32924716, DOI: 10.1080/09553002.2019.1665215.Peer-Reviewed Original ResearchConceptsNew Zealand white rabbitsAcute radiation syndromeDose-response relationshipZealand white rabbitsTBI techniquePrescribed doseAverage doseWhite rabbitsTotal body irradiation (TBI) exposureRadiation dose-response relationshipTotal body irradiation techniqueMedical countermeasure efficacyMonitor unitsLeft decubitus positionTreatment planning systemMaximal doseRadiation syndromeIndividual organ dosesAnimal modelsRadiotherapy techniquesTherapy treatment planning systemCountermeasure efficacyExperienced dosimetristDecreased attenuationDose homogeneity