Featured Publications
Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience
Gee DG. Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience. American Journal Of Psychiatry 2021, 178: 998-1013. PMID: 34734741, DOI: 10.1176/appi.ajp.2021.21090944.Peer-Reviewed Original ResearchConceptsEarly adversityProtective factorsEffects of adversityOnset of psychopathologyPathways of riskNeurodevelopmental trajectoriesMajor risk factorAdversityMental healthNeurodevelopmental pathwaysEarly environmentPsychopathologySpecific dimensionsIntervention strategiesFuture researchRisk factorsEarly risk identificationTreatment approachesImmense burdenConceptual modelDevelopmental timingResilienceOngoing refinementRiskFactors
2024
Associations between parental psychopathology and youth functional emotion regulation brain networks
Karl V, Beck D, Eilertsen E, Morawetz C, Wiker T, Aksnes E, Norbom L, Ferschmann L, MacSweeney N, Voldsbekk I, Andreassen O, Westlye L, Gee D, Engen H, Tamnes C. Associations between parental psychopathology and youth functional emotion regulation brain networks. Developmental Cognitive Neuroscience 2024, 70: 101476. PMID: 39541797, DOI: 10.1016/j.dcn.2024.101476.Peer-Reviewed Original ResearchParental psychopathologyYouth psychopathologyEmotion regulationAssociated with children's emotion regulationResting-state functional magnetic resonance imaging dataAdolescent Brain Cognitive Development StudyIntergenerational transmission of psychopathologyAssociated with lower connectivityFunctional magnetic resonance imaging dataTransmission of psychopathologyChildren's emotion regulationCognitive Development StudyMagnetic resonance imaging dataParental mental healthPFC networksPsychopathologyBrain networksParental internalizingMediation analysisCognitive aspectsMental healthConnectivity patternsIntergenerational transmissionNetwork connectivityYouthIntegrating developmental neuroscience with community-engaged approaches to address mental health outcomes for housing-insecure youth: Implications for research, practice, and policy
Foster J, Hodges H, Beloborodova A, Cohodes E, Phillips M, Anderson E, Fagbenro B, Gee D. Integrating developmental neuroscience with community-engaged approaches to address mental health outcomes for housing-insecure youth: Implications for research, practice, and policy. Developmental Cognitive Neuroscience 2024, 68: 101399. PMID: 38875770, PMCID: PMC11225708, DOI: 10.1016/j.dcn.2024.101399.Peer-Reviewed Original ResearchMental healthHousing insecurityInsecure housingHealth outcomesHousing conditionsExperiences of youthMental health of childrenImprove health outcomesCommunity-engaged approachChild mental healthMental health outcomesYouth mental healthCommunity-engaged researchHealth of childrenDevelopmental neuroscience researchUnsafe housingPolicy recommendationsYouthDevelopmental neurosciencePolicyNeurobehavioral pathwaysNeural circuitryStress literatureHousingInsecurityFuture Directions for Community-Engaged Research in Clinical Psychological Science with Youth
Giusto A, Triplett N, Foster J, Gee D. Future Directions for Community-Engaged Research in Clinical Psychological Science with Youth. Journal Of Clinical Child & Adolescent Psychology 2024, 53: 503-522. PMID: 38830059, PMCID: PMC11258858, DOI: 10.1080/15374416.2024.2359650.Peer-Reviewed Original ResearchClinical psychological scienceClinical scienceMental health problemsBurden of mental health problemsYouth mental healthPsychological scienceMental healthCommunity-engaged researchExperimental controlYouthFuture directionsClinical scientistsModes of inquiryFamily perspectiveCommunity engagementSustainability outcomesCommunity-engagedHealth problemsPublic health
2023
Leveraging the developmental neuroscience of caregiving to promote resilience among youth exposed to adversity
Gee D, Cohodes E. Leveraging the developmental neuroscience of caregiving to promote resilience among youth exposed to adversity. Development And Psychopathology 2023, 35: 2168-2185. PMID: 37929292, PMCID: PMC10872788, DOI: 10.1017/s0954579423001128.Peer-Reviewed Original ResearchCorticolimbic circuitryEmotional functioningYouth emotional functioningEmergence of psychopathologyFavorable mental health outcomesMental health outcomesYouth mental healthEmotion regulationDevelopmental neuroscienceLine of researchNeural mechanismsEarly attachmentEmotional learningEarly adversityFoster resilienceStress reactivityAdversitySensitive periodMental healthClinical interventionsResilienceFunctioningClinical implicationsYouthMajor risk factor
2022
Associations among Household and Neighborhood Socioeconomic Disadvantages, Resting-state Frontoamygdala Connectivity, and Internalizing Symptoms in Youth
Ip KI, Sisk LM, Horien C, Conley MI, Rapuano KM, Rosenberg MD, Greene AS, Scheinost D, Constable RT, Casey BJ, Baskin-Sommers A, Gee DG. Associations among Household and Neighborhood Socioeconomic Disadvantages, Resting-state Frontoamygdala Connectivity, and Internalizing Symptoms in Youth. Journal Of Cognitive Neuroscience 2022, 34: 1810-1841. PMID: 35104356, DOI: 10.1162/jocn_a_01826.Peer-Reviewed Original ResearchConceptsSocioeconomic disadvantageNeighbourhood deprivationResting-state functional connectivityInternalizing symptomsSymptoms 1 yearHigher neighborhood deprivationNeighborhood socioeconomic disadvantageCognitive Development StudyAdolescent Brain Cognitive Development (ABCD) studyEarly interventionBilateral amygdalaElevated symptomsNegative connectivitySymptomsFunctional connectivityMental healthPositive connectivityBaselineHigher internalizing symptomsFrontoparietal networkOFC regionsFunctional couplingDeleterious effectsHigh disadvantageNeeds ratioAssociations Between Early-Life Stress Exposure and Internalizing Symptomatology During the COVID-19 Pandemic: Assessing the Role of Neurobehavioral Mediators
Foster JC, Cohodes EM, Brieant AE, McCauley S, Odriozola P, Zacharek SJ, Pierre JC, Hodges HR, Kribakaran S, Haberman JT, Holt-Gosselin B, Gee DG. Associations Between Early-Life Stress Exposure and Internalizing Symptomatology During the COVID-19 Pandemic: Assessing the Role of Neurobehavioral Mediators. Biological Psychiatry Global Open Science 2022, 3: 362-373. PMID: 35959474, PMCID: PMC9356644, DOI: 10.1016/j.bpsgos.2022.07.006.Peer-Reviewed Original ResearchEarly life stressImpact of ELSResting-state functional connectivity dataEffects of ELSLife stress exposureCOVID-19 pandemicPandemic-related stressSignificant direct associationFunctional connectivity dataInternalizing symptomatologyELS exposurePsychiatric illnessOngoing COVID-19 pandemicGeneral populationSample of adultsPsychological functioningFunctional connectivityStress exposureMental healthSymptomatologyNeurobehavioral factorsAssociationEmotion regulationCOVIDDirect associationThe role of perceived threats on mental health, social, and neurocognitive youth outcomes: A multicontextual, person-centered approach.
Conley MI, Hernandez J, Salvati JM, Gee DG, Baskin-Sommers A. The role of perceived threats on mental health, social, and neurocognitive youth outcomes: A multicontextual, person-centered approach. Development And Psychopathology 2022, 35: 689-710. PMID: 35232507, PMCID: PMC9437149, DOI: 10.1017/s095457942100184x.Peer-Reviewed Original ResearchConceptsMental healthAdolescent Brain Cognitive DevelopmentDisruptive behavior symptomsLatent profile analysisPerception of threatPerson-centered approachPoor mental healthCognitive developmentDevelopmental pictureYouth outcomesNeurocognitive difficultiesYouth perceptionsBehavior symptomsSleep problemsLow threatAge 9Age 11Neurocognitive outcomesMultiple domainsMultiple contextsYouth’s neighborhoodsOutcomes 2 yearsDistinct profilesPerceptionYouth environmentTraining the Next Generation of Clinical Psychological Scientists: A Data-Driven Call to Action
Gee DG, DeYoung KA, McLaughlin KA, Tillman RM, Barch DM, Forbes EE, Krueger RF, Strauman TJ, Weierich MR, Shackman AJ. Training the Next Generation of Clinical Psychological Scientists: A Data-Driven Call to Action. Annual Review Of Clinical Psychology 2022, 18: 43-70. PMID: 35216523, PMCID: PMC9086080, DOI: 10.1146/annurev-clinpsy-081219-092500.Peer-Reviewed Original ResearchConceptsClinical psychologyClinical psychological scientistsPsychological scientistsMental health conditionsCurrent training practicesMental healthSubstance useIntervention strategiesPsychologyTraining practicesClinical scientistsMental disordersGlobal public healthCentral goalImmense burdenSpecific recommendationsAnxietyPersonalityHealth conditionsMoodScientific rigorPublic healthPsychosisHealthBurden
2021
Migration‐related trauma and mental health among migrant children emigrating from Mexico and Central America to the United States: Effects on developmental neurobiology and implications for policy
Cohodes EM, Kribakaran S, Odriozola P, Bakirci S, McCauley S, Hodges HR, Sisk LM, Zacharek SJ, Gee DG. Migration‐related trauma and mental health among migrant children emigrating from Mexico and Central America to the United States: Effects on developmental neurobiology and implications for policy. Developmental Psychobiology 2021, 63: e22158. PMID: 34292596, PMCID: PMC8410670, DOI: 10.1002/dev.22158.Peer-Reviewed Original ResearchConceptsMental healthMigration-related traumaEffects of traumaDevelopment of internalizingEarly life adversityEmotion regulationMigrant childrenTransdiagnostic mechanismsTrauma exposureExternalizing symptomatologyTraumatic experiencesRefugee childrenChildren's exposureDevelopmental neurobiologyChildrenYouthInterdisciplinary effortInternalizingTraumaImplicationsAdversityNeurobiologyContext of migrationSymptomatologyLearningParental Buffering of Stress in the Time of COVID-19: Family-Level Factors May Moderate the Association Between Pandemic-Related Stress and Youth Symptomatology
Cohodes EM, McCauley S, Gee DG. Parental Buffering of Stress in the Time of COVID-19: Family-Level Factors May Moderate the Association Between Pandemic-Related Stress and Youth Symptomatology. Research On Child And Adolescent Psychopathology 2021, 49: 935-948. PMID: 33591457, PMCID: PMC7885749, DOI: 10.1007/s10802-020-00732-6.Peer-Reviewed Original ResearchConceptsPandemic-related stressChild symptomatologyAnxiety-related symptomatologyYouth symptomatologyFamily-level factorsCross-sectional study designCOVID-19-related stressYouth mental healthEffects of exposureParental bufferingStudy designSymptomatologyMental healthChildren's exposureParental reportsHigh levelsCOVID-19COVID-19 pandemicNegative emotionsGlobal pandemicDegree of stressExposureLight of evidenceHome routinesParenting stress
2020
Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure
Cohodes EM, Kitt ER, Baskin‐Sommers A, Gee DG. Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure. Developmental Psychobiology 2020, 63: 153-172. PMID: 32227350, DOI: 10.1002/dev.21969.Peer-Reviewed Original ResearchConceptsEarly life stressFrontolimbic circuitryStress exposurePhysical health problemsEffects of stressCircuit maturationGlucocorticoid receptorHealth problemsMajority of studiesMental healthExposure influencePsychobiological effectsDimensional approachEarly experienceDifferential outcomesOutcomesSubsequent vulnerabilityRiskVast heterogeneityExposureInnervationCircuitryBrainSeverityCaregivers
2019
Predicting Mental Health in Adolescence: Frontoinsular Circuitry, Emotion in Daily Life, and Risk for Depression
Gee DG, Caballero C. Predicting Mental Health in Adolescence: Frontoinsular Circuitry, Emotion in Daily Life, and Risk for Depression. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2019, 4: 684-685. PMID: 31395211, DOI: 10.1016/j.bpsc.2019.06.004.Peer-Reviewed Original Research