2005
Dietary Patterns and the Risk of Breast Cancer
Adebamowo CA, Hu FB, Cho E, Spiegelman D, Holmes MD, Willett WC. Dietary Patterns and the Risk of Breast Cancer. Annals Of Epidemiology 2005, 15: 789-795. PMID: 16257363, DOI: 10.1016/j.annepidem.2005.01.008.Peer-Reviewed Original ResearchConceptsPrudent dietary patternDietary patternsBreast cancerNurses' Health Study IIMajor dietary patternsHealth Study IIWestern dietary patternFood frequency questionnaireInvasive breast cancerPre-menopausal womenBreast cancer riskSecular trend studiesCumulative average scoreMultivariate RRsPremenopausal womenFrequency questionnaireLowest quintileInverse associationWestern dietCancer riskOverall associationCancerFurther evaluationStudy IIRiskDietary flavonols and flavonol‐rich foods intake and the risk of breast cancer
Adebamowo CA, Cho E, Sampson L, Katan MB, Spiegelman D, Willett WC, Holmes MD. Dietary flavonols and flavonol‐rich foods intake and the risk of breast cancer. International Journal Of Cancer 2005, 114: 628-633. PMID: 15609322, DOI: 10.1002/ijc.20741.Peer-Reviewed Original ResearchConceptsMultivariate relative riskBreast cancer riskCumulative average intakeFlavonol-rich foodsIntake of beansRelative riskBreast cancerCancer riskFlavonol intakeLowest quintileInverse associationDietary flavonolsAverage intakeNurses' Health Study IIIntake of flavonolsHealth Study IIFood frequency questionnaireInvasive breast cancerSignificant inverse associationFrequency questionnaireEpidemiological studiesAnimal studiesDietary dataOverall associationFurther evaluation
2003
Premenopausal dietary carbohydrate, glycemic index, glycemic load, and fiber in relation to risk of breast cancer.
Cho E, Spiegelman D, Hunter DJ, Chen WY, Colditz GA, Willett WC. Premenopausal dietary carbohydrate, glycemic index, glycemic load, and fiber in relation to risk of breast cancer. Cancer Epidemiology Biomarkers & Prevention 2003, 12: 1153-8. PMID: 14652274.Peer-Reviewed Original ResearchConceptsBody mass indexBreast cancer riskHealth Study IIGlycemic loadCarbohydrate intakeCancer riskBreast cancerGlycemic indexDietary carbohydrateRelative riskFiber intakeNurses' Health Study IIMultivariate relative riskCorresponding relative risksFood frequency questionnaireInvasive breast cancerDietary carbohydrate intakeEarly adult lifeYoung adult womenPremenopausal womenFrequency questionnaireLean womenOverall cohortOverweight womenMass indexPremenopausal intakes of vitamins A, C, and E, folate, and carotenoids, and risk of breast cancer.
Cho E, Spiegelman D, Hunter DJ, Chen WY, Zhang SM, Colditz GA, Willett WC. Premenopausal intakes of vitamins A, C, and E, folate, and carotenoids, and risk of breast cancer. Cancer Epidemiology Biomarkers & Prevention 2003, 12: 713-20. PMID: 12917201.Peer-Reviewed Original ResearchConceptsHealth Study IIBreast cancer riskBreast cancerVitamin ACancer riskNurses' Health Study IIMultivariate relative riskFood frequency questionnaireInvasive breast cancerPrevious epidemiological studiesEarly adult lifePostmenopausal womenPremenopausal womenIncident casesHighest quintileLowest quintileRelative riskHigh intakeEpidemiological studiesNutrient intakeTotal vitaminCancerStudy IIIntakeVitamin CPremenopausal Fat Intake and Risk of Breast Cancer
Cho E, Spiegelman D, Hunter DJ, Chen WY, Stampfer MJ, Colditz GA, Willett WC. Premenopausal Fat Intake and Risk of Breast Cancer. Journal Of The National Cancer Institute 2003, 95: 1079-1085. PMID: 12865454, DOI: 10.1093/jnci/95.14.1079.Peer-Reviewed Original ResearchConceptsBreast cancer riskDietary fat intakeHigh-fat dairy foodsHealth Study IIFat intakeBreast cancerCancer riskRelative riskPremenopausal womenIncident invasive breast cancerNurses' Health Study IIElevated breast cancer riskRed meatMultivariable relative risksAnimal fat intakeFood frequency questionnaireInvasive breast cancerConfidence intervalsCase-control studyDairy foodsPremenopausal yearsPostmenopausal womenProspective studyHighest quintileLowest quintile
2002
Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studies
Missmer SA, Smith-Warner SA, Spiegelman D, Yaun SS, Adami HO, Beeson WL, van den Brandt PA, Fraser GE, Freudenheim JL, Goldbohm RA, Graham S, Kushi LH, Miller AB, Potter JD, Rohan TE, Speizer FE, Toniolo P, Willett WC, Wolk A, Zeleniuch-Jacquotte A, Hunter DJ. Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studies. International Journal Of Epidemiology 2002, 31: 78-85. PMID: 11914299, DOI: 10.1093/ije/31.1.78.Peer-Reviewed Original ResearchConceptsBreast cancer riskDairy food consumptionBreast cancerCancer riskCohort studyNon-dietary risk factorsSignificant associationFood consumptionIncident breast cancer casesEgg consumptionProspective cohort studyInvasive breast cancerDietary assessment instrumentsIntake of meatBreast cancer casesPooled analysisRisk factorsCancer casesPooled databaseNutrient intakeUsual foodCancerRed meatTotal meatWomen
2001
Validation of the Gail et al. Model of Breast Cancer Risk Prediction and Implications for Chemoprevention
Rockhill B, Spiegelman D, Byrne C, Hunter D, Colditz G. Validation of the Gail et al. Model of Breast Cancer Risk Prediction and Implications for Chemoprevention. Journal Of The National Cancer Institute 2001, 93: 358-366. PMID: 11238697, DOI: 10.1093/jnci/93.5.358.Peer-Reviewed Original ResearchConceptsInvasive breast cancerGail et alRisk factor strataBreast cancerDiscriminatory accuracyHealth StudyModest discriminatory accuracyNurses' Health StudySubset of womenBreast cancer casesBreast cancer risk predictionNet health benefitCancer risk predictionTamoxifen useCancer casesPrevention optionsConcordance statisticClinical counselingCancerYoung womenWhite womenRisk estimatesWomenHealth benefitsRisk prediction
2000
Electric Blanket Use and Breast Cancer in the Nurses' Health Study
Laden F, Neas LM, Tolbert PE, Holmes MD, Hankinson SE, Spiegelman D, Speizer FE, Hunter DJ. Electric Blanket Use and Breast Cancer in the Nurses' Health Study. American Journal Of Epidemiology 2000, 152: 41-49. PMID: 10901328, DOI: 10.1093/aje/152.1.41.Peer-Reviewed Original ResearchConceptsElectric blanket useNurses' Health StudyBreast cancerHealth StudyBlanket useRelative riskEstrogen receptor-positive breast cancerReceptor-positive breast cancerBreast cancer risk factorsMultivariate relative riskInvasive breast cancerCancer risk factorsAge-adjusted analysesBreast cancer riskLong-term useElectric blanketBiennial questionnairesRisk factorsRetrospective analysisCancer riskProspective analysisCancerMultivariate modelSmall riskConfidence intervals
1999
Alcohol consumption in relation to breast cancer risk in a cohort of United States women 25-42 years of age.
Garland M, Hunter DJ, Colditz GA, Spiegelman DL, Manson JE, Stampfer MJ, Willett WC. Alcohol consumption in relation to breast cancer risk in a cohort of United States women 25-42 years of age. Cancer Epidemiology Biomarkers & Prevention 1999, 8: 1017-21. PMID: 10566558.Peer-Reviewed Original ResearchConceptsBreast cancer riskMultivariate relative riskAlcohol consumptionCancer riskRelative riskBreast cancerDrinks/weekInvasive breast cancerModerate alcohol consumptionMore drinks/weekAverage lifetime alcohol consumptionLifetime alcohol consumptionWomen age 25Past alcohol consumptionYears of agePostmenopausal womenPremenopausal womenWomen 25Age 25Young womenHeavy drinkingAge 23Drinking levelsWomenFurther studies
1998
Physical Activity and Breast Cancer Risk in a Cohort of Young Women
Rockhill B, Willett W, Hunter D, Manson J, Hankinson S, Spiegelman D, Colditz G. Physical Activity and Breast Cancer Risk in a Cohort of Young Women. Journal Of The National Cancer Institute 1998, 90: 1555-1160. PMID: 9701365, DOI: 10.1093/jnci/90.15.1155.Peer-Reviewed Original ResearchConceptsBreast cancer riskHealth Study IIPhysical activityRelative riskBreast cancerCancer riskNurses' Health Study IIRR of cancerBreast cancer preventionInvasive breast cancerStrenuous physical activityConfidence intervalsLate adolescenceNonoccupational physical activityYoung adult womenProspective studyNonoccupational activitiesActive womenCancer preventionReduced riskStrenuous activityAdult womenAge 18Logistic regressionYoung womenAlcohol and Breast Cancer in Women: A Pooled Analysis of Cohort Studies
Smith-Warner SA, Spiegelman D, Yaun SS, van den Brandt PA, Folsom AR, Goldbohm RA, Graham S, Holmberg L, Howe GR, Marshall JR, Miller AB, Potter JD, Speizer FE, Willett WC, Wolk A, Hunter DJ. Alcohol and Breast Cancer in Women: A Pooled Analysis of Cohort Studies. JAMA 1998, 279: 535-540. PMID: 9480365, DOI: 10.1001/jama.279.7.535.Peer-Reviewed Original ResearchConceptsInvasive breast cancerAlcohol intakeBreast cancerAlcohol consumptionRelative riskIncident invasive breast cancerMultivariate-adjusted relative riskIncident breast cancer casesBeverage-specific alcohol consumptionMultivariate relative riskTotal alcohol intakeFood frequency questionnaireBreast cancer incidenceBreast cancer riskBreast cancer casesRandom-effects modelLong-term intakeCohort studyFrequency questionnaireProspective studyPooled analysisCancer incidenceDiet assessment instrumentsCancer casesNondietary factors
1997
Geographic Variation in Breast Cancer Incidence Rates in a Cohort of U.S. Women
Laden F, Hankinson S, Spiegelman D, Neas L, Colditz G, Hunter D, Manson J, Byrne C, Rosner B, Speizer F. Geographic Variation in Breast Cancer Incidence Rates in a Cohort of U.S. Women. Journal Of The National Cancer Institute 1997, 89: 1373-1378. PMID: 9308708, DOI: 10.1093/jnci/89.18.1373.Peer-Reviewed Original ResearchConceptsBreast cancer incidence ratesCancer incidence ratesHealth Study cohortRisk factorsIncidence ratePostmenopausal womenRelative riskHealth StudyNurses' Health Study cohortAge-adjusted breast cancer incidence ratesBreast cancer risk factorsNurses' Health StudyMultivariate-adjusted analysesAge-adjusted riskBreast cancer incidenceInvasive breast cancerBreast cancer mortalityCancer risk factorsPremenopausal womenStudy cohortIncident casesCancer mortalityExcess riskCancer incidenceBreast cancer