2023
“They need people to actually show up in their lives:” deploying community health workers to improve mental health and substance use outcomes among PLWH
Marotta P, Carter C, Hu Y, Wang V, Rucker D, Jones J, Gross G, Brown T, Spiegelman D, Humphries D. “They need people to actually show up in their lives:” deploying community health workers to improve mental health and substance use outcomes among PLWH. Journal Of HIV/AIDS & Social Services 2023, 22: 163-185. DOI: 10.1080/15381501.2024.2385988.Peer-Reviewed Original ResearchCommunity health workersHarm reduction servicesMental healthHealth workersSubstance use disordersEnhanced coordination of careReduction servicesCoordination of careAdherence to anti-retroviral treatmentMental health careImprove mental healthMental health problemsSubstance usePoor MHHIV careHIV engageHealth careAnti-retroviral treatmentHousing insecuritySubstance use outcomesHIV treatmentImplementation strategiesHealth problemsPLWHCare
2022
Iron supplementation and paediatric HIV disease progression: a cohort study among children receiving routine HIV care in Dar es Salaam, Tanzania
Andersen CT, Duggan CP, Manji K, Seage GR, Spiegelman D, Perumal N, Ulenga N, Fawzi WW. Iron supplementation and paediatric HIV disease progression: a cohort study among children receiving routine HIV care in Dar es Salaam, Tanzania. International Journal Of Epidemiology 2022, 51: 1533-1543. PMID: 35167662, PMCID: PMC9557856, DOI: 10.1093/ije/dyac017.Peer-Reviewed Original ResearchConceptsDisease stage progressionIron supplementationStage progressionCohort studyDisease progressionRoutine HIV careHIV disease progressionProspective cohort studyManagement of anemiaRisk of anemiaHigher hazard rateProportional hazards modelIron supplement useDar es SalaamHaematological outcomesAntiretroviral therapyHIV careClinic visitsSupportive careAntiretroviral treatmentClinical outcomesClinical visitsAnemia statusSupplement useVital status
2020
Getting to 90–90–90: Experiences from the MaxART Early Access to ART for All (EAAA) Trial in Eswatini
Walsh F, Khan S, Bärnighausen T, Hettema A, Lejeune C, Mazibuko S, Mlambo CK, Reis R, Fleming Y, Khumalo G, Zwane M, Okello V, Spiegelman D. Getting to 90–90–90: Experiences from the MaxART Early Access to ART for All (EAAA) Trial in Eswatini. Current HIV/AIDS Reports 2020, 17: 324-332. PMID: 32474844, DOI: 10.1007/s11904-020-00501-6.Peer-Reviewed Original ResearchConceptsTreatment guidelinesRoutine viral load monitoringNational HIV careViral load monitoringAdolescent malesSystem-level barriersEarly accessInnovative community-based approachesPublic health systemCommunity outreach strategiesImplementation science researchART initiationHIV careHIV testHIV testingMiddle-income countriesUNAIDS 90Adult menMultiple interventionsHealth systemAdolescent femalesEswatini MinistryTrialsFast trackBaseline data
2012
Elevated alanine aminotransferase in antiretroviral‐naïve HIV‐infected African patients: magnitude and risk factors
Nagu T, Kanyangarara M, Hawkins C, Hertmark E, Chalamila G, Spiegelman D, Mugusi F, Fawzi W. Elevated alanine aminotransferase in antiretroviral‐naïve HIV‐infected African patients: magnitude and risk factors. HIV Medicine 2012, 13: 541-548. PMID: 22416813, PMCID: PMC3391335, DOI: 10.1111/j.1468-1293.2012.01006.x.Peer-Reviewed Original ResearchConceptsElevated alanine aminotransferaseIU/LAlanine aminotransferaseAntiretroviral therapyHigh riskWorld Health Organization clinical stageCD4 T-lymphocyte countFirst-line antiretroviral therapyHepatitis B virus coinfectionALT measurementsLow-density lipoprotein cholesterolLog-binomial regression modelsB virus coinfectionT-lymphocyte countsART-naïve HIVCells/μLHepatotoxic side effectsCurrent tuberculosis (TB) treatmentResource-limited settingsCross-sectional analysisAdvanced immunosuppressionHBV coinfectionART-naïveHIV careLipoprotein cholesterol