1998
Molecular and Geographic Patterns of Tuberculosis Transmission After 15 Years of Directly Observed Therapy
Bishai W, Graham N, Harrington S, Pope D, Hooper N, Astemborski J, Sheely L, Vlahov D, Glass G, Chaisson R. Molecular and Geographic Patterns of Tuberculosis Transmission After 15 Years of Directly Observed Therapy. JAMA 1998, 280: 1679-1684. PMID: 9831999, DOI: 10.1001/jama.280.19.1679.Peer-Reviewed Original ResearchMeSH KeywordsAdultBaltimoreCluster AnalysisContact TracingDNA FingerprintingFemaleHumansMaleMolecular EpidemiologyMycobacterium tuberculosisPolymorphism, Restriction Fragment LengthProspective StudiesRegression AnalysisRisk FactorsSocioeconomic FactorsTuberculosisConceptsEpidemiologic linkObserved therapyTuberculosis casesTuberculosis transmissionRecent transmissionTraditional contact investigationsCulture-positive tuberculosisTuberculosis control measuresCases of tuberculosisCommon risk factorsProportion of casesHigher drug useLow socioeconomic statusProportion of diseaseContact investigationEpidemiologic evidenceM tuberculosisRisk factorsEpidemiologic comparisonsEpidemiologic linkageTuberculosis accountsInformation system dataTraditional contact tracingDrug useEarly identification
1997
Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression
Smith M, Dean M, Carrington M, Winkler C, Huttley G, Lomb D, Goedert J, O'Brien T, Jacobson L, Kaslow R, Buchbinder S, Vittinghoff E, Vlahov D, Hoots K, Hilgartner M, Study H, San Francisco City Cohort ALIVE Study M, O'Brien S. Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression. Science 1997, 277: 959-965. PMID: 9252328, DOI: 10.1126/science.277.5328.959.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeBlack PeopleCohort StudiesDisease ProgressionGenotypeHaplotypesHeterozygoteHIV InfectionsHIV-1HumansMutationPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthPolymorphism, Single-Stranded ConformationalProportional Hazards ModelsReceptors, CCR2Receptors, CCR5Receptors, ChemokineReceptors, CytokineReceptors, HIVSurvival AnalysisWhite PeopleConceptsHIV-1 infectionCCR2-64IDisease progressionHIV-1 disease progressionHIV-1-infected individualsLong-term survivorsCCR2-64I alleleReceptor geneChemokine receptor genesAIDS 2CCR2 chemokineSyndrome cohortAIDS patientsCCR5-Delta32Human immunodeficiencyChemokine receptorsCCR5 variantsCCR2CCR5InfectionIndependent effectsAfrican AmericansMutant genotypesProgressionGenetic association analysis
1992
Genetic Vulnerability to Drug Abuse: The D2 Dopamine Receptor Taq I B1 Restriction Fragment Length Polymorphism Appears More Frequently in Polysubstance Abusers
Smith S, O'Hara B, Persico A, Gorelick D, Newlin D, Vlahov D, Solomon L, Pickens R, Uhl G. Genetic Vulnerability to Drug Abuse: The D2 Dopamine Receptor Taq I B1 Restriction Fragment Length Polymorphism Appears More Frequently in Polysubstance Abusers. JAMA Psychiatry 1992, 49: 723-727. PMID: 1355337, DOI: 10.1001/archpsyc.1992.01820090051009.Peer-Reviewed Original ResearchAlcoholismAllelesFemaleGenetic MarkersHumansMalePolymorphism, Restriction Fragment LengthReceptors, DopamineSubstance-Related Disorders