2001
Human Immunodeficiency Virus Seroconversion and Evolution of the Hepatitis C Virus Quasispecies
Mao Q, Ray S, Laeyendecker O, Ticehurst J, Strathdee S, Vlahov D, Thomas D. Human Immunodeficiency Virus Seroconversion and Evolution of the Hepatitis C Virus Quasispecies. Journal Of Virology 2001, 75: 3259-3267. PMID: 11238852, PMCID: PMC114119, DOI: 10.1128/jvi.75.7.3259-3267.2001.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHCV quasispeciesHypervariable region 1HIV seroconversionChronic hepatitis C virus (HCV) infectionE2 hypervariable region 1Hepatitis C virus infectionHuman immunodeficiency virus (HIV) seroconversionRapid HIV disease progressionHepatitis C virus quasispeciesHIV infection altersHIV-associated diseaseChronic HCV infectionC virus infectionHIV disease progressionHCV infectionHCV RNASerum levelsLiver diseaseImmunodeficiency virusDisease progressionRapid progressionVirus infectionNumber of subjectsHCV sequences
2000
The Natural History of Hepatitis C Virus Infection: Host, Viral, and Environmental Factors
Thomas D, Astemborski J, Rai R, Anania F, Schaeffer M, Galai N, Nolt K, Nelson K, Strathdee S, Johnson L, Laeyendecker O, Boitnott J, Wilson L, Vlahov D. The Natural History of Hepatitis C Virus Infection: Host, Viral, and Environmental Factors. JAMA 2000, 284: 450-456. PMID: 10904508, DOI: 10.1001/jama.284.4.450.Peer-Reviewed Original ResearchConceptsEnd-stage liver diseaseInjection drug useHepatitis C virus infectionC virus infectionHuman immunodeficiency virusViral clearanceHCV infectionLiver diseaseDrug usePersistent viremiaVirus infectionCases of ESLDRisk of ESLDCommunity-based prospective cohort studyAntibody-positive test resultPresence of ascitesProspective cohort studyCause of deathUtilization of treatmentMajority of adultsSemiannual visitsCohort studyHCV RNAEsophageal varicesImmunodeficiency virus
1997
Persistence and Clinical Significance of Hepatitis G Virus Infections in Injecting Drug Users
Thomas D, Nakatsuji Y, Shih J, Alter H, Nelson K, Astemborski J, Lyles C, Vlahov D. Persistence and Clinical Significance of Hepatitis G Virus Infections in Injecting Drug Users. The Journal Of Infectious Diseases 1997, 176: 586-592. PMID: 9291303, DOI: 10.1086/514078.Peer-Reviewed Original ResearchConceptsHepatitis G virus infectionG virus infectionHGV RNAHGV infectionVirus infectionDrug usersLiver-related enzymesRecent serum sampleInjecting Drug UsersHepatic inflammationAcute infectionSerum levelsLiver diseaseClinical significanceNegative participantsSerial samplesDrug useInfectionPrior visitSerum samplesIDUsPrior specimensRecent visitVisitsYears
1993
Increased Mortality Associated With Vitamin A Deficiency During Human Immunodeficiency Virus Type 1 Infection
Semba R, Graham N, Caiaffa W, Margolick J, Clement L, Vlahov D. Increased Mortality Associated With Vitamin A Deficiency During Human Immunodeficiency Virus Type 1 Infection. JAMA Internal Medicine 1993, 153: 2149-2154. PMID: 8379807, DOI: 10.1001/archinte.1993.00410180103012.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus type 1 (HIV-1) infectionHIV-1-seropositive individualsVirus type 1 infectionCD4 T cellsHIV-1 infectionType 1 infectionPlasma vitaminT cellsHIV-1-seronegative individualsMean plasma vitaminLow CD4 levelsIntravenous drug usersHIV-seropositive participantsBlood cell countImportant risk factorNormal immune functionMumol/LCD4 levelsSeronegative individualsImmunologic statusSerologic markersClinical outcomesLiver diseaseSeropositive individualsIncreased Mortality
1989
Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (hiv) epidemic in new york city
Novick D, Trigg H, Jarlais D, Friedman S, Vlahov D, Kreek M. Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (hiv) epidemic in new york city. Journal Of Medical Virology 1989, 29: 181-185. PMID: 2614398, DOI: 10.1002/jmv.1890290307.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusParenteral drug usersHispanic patientsDrug usersHIV infectionHuman immunodeficiency virus (HIV) epidemicImmune deficiency syndromeMultiple logistic regressionUse of cocaineNew York CityWhite patientsBlack patientsLiver diseaseImmunodeficiency virusDeficiency syndromeHIV epidemicCocaine injectionHigh prevalencePatientsDrug useEtiologic agentMedical problemsLogistic regressionExtensive epidemicHeroin