2020
An improved and highly selective fluorescence assay for measuring phosphatidylserine decarboxylase activity Fluorescence detection of PS decarboxylase activity
Choi JY, Black R, Lee H, Di Giovanni J, Murphy RC, Ben Mamoun C, Voelker DR. An improved and highly selective fluorescence assay for measuring phosphatidylserine decarboxylase activity Fluorescence detection of PS decarboxylase activity. Journal Of Biological Chemistry 2020, 295: 9211-9222. PMID: 32430397, PMCID: PMC7335775, DOI: 10.1074/jbc.ra120.013421.Peer-Reviewed Original Research
2006
The plasma membrane permease PfNT1 is essential for purine salvage in the human malaria parasite Plasmodium falciparum
Bissati K, Zufferey R, Witola WH, Carter NS, Ullman B, Mamoun C. The plasma membrane permease PfNT1 is essential for purine salvage in the human malaria parasite Plasmodium falciparum. Proceedings Of The National Academy Of Sciences Of The United States Of America 2006, 103: 9286-9291. PMID: 16751273, PMCID: PMC1482602, DOI: 10.1073/pnas.0602590103.Peer-Reviewed Original ResearchConceptsParasite plasma membraneHuman malaria parasite Plasmodium falciparumMalaria parasite Plasmodium falciparumParasite Plasmodium falciparumPurine salvagePlasma membraneLethal mutantsPlasmodium falciparumInosine transportPurine sourceSpecialized transportersTransgenic parasitesHost enzymesPfNT1Essential nutrientsPotential therapeutic targetParasitesPhysiological conditionsHost purinesInfected erythrocytesSequential pathwaySevere reductionTherapeutic targetP. falciparumHuman erythrocytes