2023
Appetitive and aversive cue reactivities differentiate neural subtypes of alcohol drinkers
Chen Y, Li C. Appetitive and aversive cue reactivities differentiate neural subtypes of alcohol drinkers. Addiction Neuroscience 2023, 7: 100089. PMID: 37483686, PMCID: PMC10358306, DOI: 10.1016/j.addicn.2023.100089.Peer-Reviewed Original ResearchCue responsesMonetary incentive delay taskDistinct neural correlatesDistinct neural underpinningsIncentive delay taskNegative emotional statesMid-cingulate cortexMedial cortical regionsDrug cuesNeural underpinningsCue reactivityNeural correlatesSubjective urgeAlcohol expectanciesDelay taskEmotional statesLoss processingSensation seekingVentral striatumAlcohol drinkersAversive componentCortical regionsAversive responsesSubstance misusePotential subtypes
2014
Cognitive Control in Opioid Dependence and Methadone Maintenance Treatment
Liao DL, Huang CY, Hu S, Fang SC, Wu CS, Chen WT, Lee TS, Chen PC, Li CS. Cognitive Control in Opioid Dependence and Methadone Maintenance Treatment. PLOS ONE 2014, 9: e94589. PMID: 24727743, PMCID: PMC3984179, DOI: 10.1371/journal.pone.0094589.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentOpioid dependencePost-error slowingStop-signal reaction timePsychiatric comorbidityMaintenance treatmentCognitive controlAbstinence durationOpioid-dependent individualsResponse inhibitionHealthy control participantsMethadone treatmentSignal reaction timeCognitive dysfunctionMMT groupPsychiatric clinicSubstance misuseLonger abstinenceComorbiditiesHC participantsControl participantsDependent individualsSignal taskBehavioral adjustmentPublic healthError-related functional connectivity of the thalamus in cocaine dependence
Zhang S, Hu S, Bednarski SR, Erdman E, Li CS. Error-related functional connectivity of the thalamus in cocaine dependence. NeuroImage Clinical 2014, 4: 585-592. PMID: 24936409, PMCID: PMC4053644, DOI: 10.1016/j.nicl.2014.01.015.Peer-Reviewed Original ResearchConceptsVentral medial prefrontal cortexFunctional connectivityCognitive controlGeneralized psychophysiological interaction analysisTask-related processesPsychophysiological interaction analysisSubgenual anterior cingulate cortexCocaine dependenceMedial prefrontal cortexAnterior cingulate cortexError processingExecutive functionCocaine-dependent patientsPrefrontal cortexCingulate cortexRelated activationSubstance misuseCocaine useDrug useThalamic connectivity