2018
Structural and functional cerebral bases of diminished inhibitory control during healthy aging
Hu S, Ide JS, Chao HH, Castagna B, Fischer KA, Zhang S, Li C. Structural and functional cerebral bases of diminished inhibitory control during healthy aging. Human Brain Mapping 2018, 39: 5085-5096. PMID: 30113124, PMCID: PMC6287913, DOI: 10.1002/hbm.24347.Peer-Reviewed Original ResearchConceptsProlonged stop signal reaction timeStop-signal reaction timeAge-related reductionInhibitory controlFunctional changesPrefrontal cortexAge-related diminutionSignal taskRight dorsolateral prefrontal cortexSame brain regionsFunctional magnetic resonance imagingMagnetic resonance imagingMedial prefrontal cortexInferior parietal cortexResponse inhibitionDorsolateral prefrontal cortexInferior frontal cortexDiminished inhibitory controlCerebral changesStructure-function associationsSignal reaction timeCaudate headAge-related differencesStop-signal taskFrontal cortex
2016
Association of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers
Hu S, Zhang S, Chao HH, Krystal JH, Li CS. Association of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers. Alcohol Clinical And Experimental Research 2016, 40: 319-328. PMID: 26833431, PMCID: PMC4742397, DOI: 10.1111/acer.12964.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestYears of drinkingStop-signal reaction timeAlcohol useAge-related changesAlcohol misuseInhibitory controlAUDIT scoresDrinking problemsNondependent drinkersProlonged stop signal reaction timeChronic alcohol useAnterior cingulate cortexPresupplementary motor areaDisorders Identification TestRight inferior frontal gyrusResponse inhibitionSuperior temporal gyrusYoung adult social drinkersFunctional magnetic resonanceAdult social drinkersSignal reaction timeCerebral responsesInferior frontal gyrusHigher AUDIT