2017
Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review
McGregor AJ, Beauchamp GA, Wira CR, Perman SM, Safdar B. Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review. Western Journal Of Emergency Medicine 2017, 18: 1079-1090. PMID: 29085541, PMCID: PMC5654878, DOI: 10.5811/westjem.2017.8.34997.Peer-Reviewed Original ResearchConceptsClinical practiceAcute ischemic strokeAcute myocardial infarctionEmergency medicineBrief narrative reviewSex-based researchEmergency medicine researchIschemic strokeTherapy administrationPatient sexMyocardial infarctionEmergency carePatient careNarrative reviewEvidence-based researchCase-based scenariosNational InstituteBiological variablesCareSexMedicine researchSABVInfarctionBody of literatureStroke
2016
The Advanced Reperfusion Era: Implications for Emergency Systems of Ischemic Stroke Care
Miller JB, Merck LH, Wira CR, Meurer WJ, Schrock JW, Nomura JT, Siket MS, Madsen TE, Wright DW, Panagos PD, Lewandowski C. The Advanced Reperfusion Era: Implications for Emergency Systems of Ischemic Stroke Care. Annals Of Emergency Medicine 2016, 69: 192-201. PMID: 27600649, DOI: 10.1016/j.annemergmed.2016.06.042.Peer-Reviewed Original ResearchConceptsStroke careLarge-vessel ischemic strokeEndovascular stroke treatmentIschemic stroke careEmergency medicine cliniciansEndovascular careReperfusion eraIschemic strokeStroke treatmentEndovascular treatmentTreatment paradigmLeading causeMedicine cliniciansTimely treatmentCarePatientsHospitalTreatmentMorbidityStrokeMortalityCliniciansCentral role
2009
Surviving sepsis in low-income and middle-income countries: new directions for care and research
Becker JU, Theodosis C, Jacob ST, Wira CR, Groce NE. Surviving sepsis in low-income and middle-income countries: new directions for care and research. The Lancet Infectious Diseases 2009, 9: 577-582. PMID: 19695494, DOI: 10.1016/s1473-3099(09)70135-5.Peer-Reviewed Original ResearchConceptsSepsis managementMiddle-income countriesBurden of sepsisPrevalence of HIVAppropriate antibiotic useTreatment of sepsisRecognition of sepsisEvidence-based interventionsSepsis careSystemic inflammationComorbid conditionsTreatment algorithmAntibiotic useTreatment responseSepsisHealth personnelMost LMICsAccurate diagnosisInvasive technologiesLMICsCareLaboratory testingResource-limited environmentsHIVInflammation
2008
Clinical risk stratification for gastrointestinal hemorrhage: still no consensus
Wira C, Sather J. Clinical risk stratification for gastrointestinal hemorrhage: still no consensus. Critical Care 2008, 12: 154. PMID: 18533048, PMCID: PMC2481453, DOI: 10.1186/cc6900.Peer-Reviewed Original ResearchConceptsGastrointestinal hemorrhageRisk stratificationLower gastrointestinal hemorrhageComprehensive practice guidelinesClinical risk stratificationHospital complicationsUnstable comorbiditiesOngoing bleedingStable patientsCritical carePractice guidelinesLower riskBLEED criteriaLack of consensusHemorrhagePatientsFurther investigationBleedingComorbiditiesPrevious studiesComplicationsStratificationCare