Featured Publications
Racial and ethnic differences in alcohol, cannabis, and illicit substance use treatment: a systematic review and narrative synthesis of studies done in the USA
Jordan A, Quainoo S, Nich C, Babuscio TA, Funaro MC, Carroll KM. Racial and ethnic differences in alcohol, cannabis, and illicit substance use treatment: a systematic review and narrative synthesis of studies done in the USA. The Lancet Psychiatry 2022, 9: 660-675. PMID: 35752192, DOI: 10.1016/s2215-0366(22)00160-2.Peer-Reviewed Original ResearchConceptsSubstance use outcomesTreatment initiationJoanna Briggs Institute appraisal toolsSystematic reviewSubstance use disordersSignificant differencesSubstance use treatmentDissemination of treatmentUncontrolled trialsClinical trialsBaseline differencesStudy qualityInclusion criteriaUse disordersRCTsNarrative synthesisSocial determinantsUse treatmentAppraisal toolLatinx adultsEthnic differencesEthnic populationsOutcomesTrialsLatinx populations
2023
Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use
Loya J, Babuscio T, Nich C, Alessi S, Rash C, Kiluk B. Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use. Drug And Alcohol Dependence 2023, 248: 109947. PMID: 37276806, PMCID: PMC10498479, DOI: 10.1016/j.drugalcdep.2023.109947.Peer-Reviewed Original ResearchConceptsUrine drug screensClinical trialsMeaningful endpointsCocaine useLong-term clinical benefitBetter long-term outcomesDrug screensPsychosocial functioningNegative urine drug screensLong-term outcomesRandomized clinical trialsFuture clinical trialsBetter psychosocial functioningClinical benefitPharmacological treatmentContinuous abstinenceTreatment periodTreatment respondersSustained abstinenceSubstance useTrialsTreatmentMeaningful thresholdPooled datasetAbstinenceBreaking through social determinants of health: Results from a feasibility study of Imani Breakthrough, a community developed substance use intervention for Black and Latinx people
Jordan A, Costa M, Nich C, Swarbrick M, Babuscio T, Wyatt J, O'Connell M, Guy K, Blackman K, Anderson R, Reis G, Ocasio L, Crespo M, Bellamy C. Breaking through social determinants of health: Results from a feasibility study of Imani Breakthrough, a community developed substance use intervention for Black and Latinx people. Journal Of Substance Use And Addiction Treatment 2023, 153: 209057. PMID: 37207836, DOI: 10.1016/j.josat.2023.209057.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanFeasibility StudiesHealth PromotionHispanic or LatinoHumansSocial Determinants of HealthSubstance-Related DisordersConceptsSocial determinantsMental Health Services AdministrationDimensions of wellnessCommunity-based participatory research approachRate of deathHealth Services AdministrationDrug overdose ratesSubset of participantsSubstance use interventionsWeek 12Opioid overdoseOverdose ratesSubstance misuseEthnic disparitiesDisparity gapParticipatory research approachAddiction servicesSubstance abuseWeeks of educationHealth equityMental healthSubstance useLatinx peopleIntervention programsServices AdministrationThe Rise and Fall of Substance Use During Treatment: Applying Recency and Expectancy Principles to Daily Substance Use Patterns
Benitez B, Frankforter T, Nich C, Kiluk BD. The Rise and Fall of Substance Use During Treatment: Applying Recency and Expectancy Principles to Daily Substance Use Patterns. Psychology Of Addictive Behaviors 2023, 37: 235-246. PMID: 35201805, PMCID: PMC9399316, DOI: 10.1037/adb0000824.Peer-Reviewed Original ResearchMeSH KeywordsAdultBayes TheoremCognitive Behavioral TherapyFemaleHumansMaleMotivationSubstance-Related DisordersTreatment OutcomeConceptsCognitive behavioral therapySubstance use disordersSubstance use patternsSubstance useTherapy sessionsRandomized clinical trial dataComputerized cognitive behavioral therapyClinical trial dataOutpatient SUD treatmentNext therapy sessionClinical trialsTherapy daysTreatment mechanismsSUD treatmentUse disordersTreatment efficacyTreatment sessionsTherapeutic contactDaily substance useTrial dataSecondary analysisSUD severityBehavioral therapyDrug typeWeekly proportion
2021
Detecting change in psychiatric functioning in clinical trials for cocaine use disorder: sensitivity of the Addiction Severity Index and Brief Symptom Inventory
Kiluk BD, Roos CR, Aslan M, Gueorguieva R, Nich C, Babuscio TA, Carroll KM. Detecting change in psychiatric functioning in clinical trials for cocaine use disorder: sensitivity of the Addiction Severity Index and Brief Symptom Inventory. Drug And Alcohol Dependence 2021, 228: 109070. PMID: 34600247, PMCID: PMC8595796, DOI: 10.1016/j.drugalcdep.2021.109070.Peer-Reviewed Original ResearchConceptsAddiction Severity IndexGlobal Severity IndexPsychiatric composite scoreClinical trialsCocaine useCocaine use disorderPsychiatric functioningBrief Symptom InventorySeverity IndexUse disordersASI psychiatric composite scoreSymptom InventoryEffect sizeStart of treatmentComposite scoreClinical trial participantsWeek 12Functional outcomeTreatment periodTrial participantsPsychiatric problemsDrug usePotential functional benefitsMedium effect sizeSubstance usersTo the Editor: Our response to “Substance use improvement depends on Race/Ethnicity: Outpatient treatment disparities observed in a large US national sample”
Jordan A, Nich C, Babuscio T, Quainoo S, Carroll K. To the Editor: Our response to “Substance use improvement depends on Race/Ethnicity: Outpatient treatment disparities observed in a large US national sample”. Drug And Alcohol Dependence 2021, 223: 108670. PMID: 33812693, DOI: 10.1016/j.drugalcdep.2021.108670.Peer-Reviewed Original Research
2020
A feasibility study providing substance use treatment in the Black church
Jordan A, Babuscio T, Nich C, Carroll KM. A feasibility study providing substance use treatment in the Black church. Journal Of Substance Use And Addiction Treatment 2020, 124: 108218. PMID: 33771290, DOI: 10.1016/j.jsat.2020.108218.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlack or African AmericanCognitive Behavioral TherapyFeasibility StudiesHumansSubstance-Related DisordersConceptsTechnology-based treatmentsClinical trialsSUD treatmentBlack adultsNonrandomized feasibility studyUrine toxicology screenHealth care disparitiesEvidence-based interventionsDSM-5 criteriaAdequate numberCognitive behavioral therapyDisseminable strategyUndertreated populationToxicology screenCurrent SUDCare disparitiesHealth advisorsBehavioral therapySubstance useMean numberTreatmentHigh uptakeFeasibility studyCBT4CBTTrialsShort- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders
Roos CR, Carroll KM, Nich C, Frankforter T, Kiluk BD. Short- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders. Drug And Alcohol Dependence 2020, 212: 108044. PMID: 32422538, PMCID: PMC7293942, DOI: 10.1016/j.drugalcdep.2020.108044.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedSubstance-Related DisordersTherapy, Computer-AssistedTime FactorsTreatment OutcomeConceptsCognitive behavioral therapyComputerized cognitive behavioral therapyPerson cognitive-behavioural therapySubstance use disordersMediation effectAlcohol use disorderComputer-delivered cognitive behavioural therapyUse disordersSame mediation effectSubstance-related copingCoping Strategies ScaleSignificant mediation effectMechanisms of changeMediational modelCoping skillsStrategies ScaleCBT4CBTStatistical mediatorCopingDrug use disordersSubstance useHeavy drinkingDisordersLong-term changesLong-term increaseComputerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT.
Tetrault JM, Holt SR, Cavallo DA, O'Connor PG, Gordon MA, Corvino JK, Nich C, Carroll KM. Computerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT. Journal Of Addiction Medicine 2020, 14: e303-e309. PMID: 32371660, DOI: 10.1097/adm.0000000000000663.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismCognitive Behavioral TherapyCrisis InterventionFeasibility StudiesHumansMass ScreeningPrimary Health CareReferral and ConsultationSubstance-Related DisordersConceptsSubstance use disordersComputerized cognitive behavioral therapySubstance useCognitive behavioral therapySelf-reported substance useUse disordersTechnology-based treatmentsPrimary care settingSubstance use outcomesIntegrated addictions treatmentTechnology-based interventionsBehavioral therapyPrimary care practicesOverall positive outcomeSUD interventionsBrief interventionUnhealthy alcohol useDays abstinentPositive outcomesUse outcomesCare settingsAlcohol useStandard careAddiction treatmentTreatment settings
2018
Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial.
Paris M, Silva M, Añez-Nava L, Jaramillo Y, Kiluk BD, Gordon MA, Nich C, Frankforter T, Devore K, Ball SA, Carroll KM. Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial. American Journal Of Public Health 2018, 108: 1535-1542. PMID: 30252519, PMCID: PMC6187780, DOI: 10.2105/ajph.2018.304571.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive Behavioral TherapyConnecticutCulturally Competent CareFemaleHispanic or LatinoHumansInternetMaleSubstance-Related DisordersTreatment OutcomeConceptsSubstance use disordersCognitive-behavioral treatmentUse disordersSubstance use outcomesClinical trialsWeb-based cognitive behavioral therapyCurrent substance use disorderUse outcomesRandomized clinical trialsStandard outpatient treatmentEvidence-based treatmentsCognitive behavioral therapyPrimary outcomeStandard treatmentOutpatient treatmentStandard outpatientTreatment completionHealth disparitiesBehavioral therapyBehavioral treatmentAddiction treatmentTreatment-seeking individualsGreater reductionTreatmentDisordersRandomized Clinical Trial of Computerized and Clinician-Delivered CBT in Comparison With Standard Outpatient Treatment for Substance Use Disorders: Primary Within-Treatment and Follow-Up Outcomes
Kiluk BD, Nich C, Buck MB, Devore KA, Frankforter TL, LaPaglia DM, Muvvala SB, Carroll KM. Randomized Clinical Trial of Computerized and Clinician-Delivered CBT in Comparison With Standard Outpatient Treatment for Substance Use Disorders: Primary Within-Treatment and Follow-Up Outcomes. American Journal Of Psychiatry 2018, 175: 853-863. PMID: 29792052, PMCID: PMC6120780, DOI: 10.1176/appi.ajp.2018.17090978.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareCognitive Behavioral TherapyFemaleFollow-Up StudiesHumansMaleSubstance-Related DisordersTherapy, Computer-AssistedTreatment OutcomeConceptsCognitive behavioral therapySubstance use disordersComputer-based cognitive behavioral therapyUse disordersMinimal clinical monitoringTreatment-seeking populationTreatment-seeking outpatientsDSM-IV-TR criteriaCBT groupFrequency of substanceStandard outpatient careCBT4CBTStand-alone treatmentDiverse sampleStandard outpatient treatmentCurrent substance use disorderBehavioral conceptsBetter learningSubstance abuseHeterogeneous sampleUp OutcomesHigh dropout ratePrevious trialsSix-month followClinical trials
2016
Performance-Based Contingency Management in Cognitive Remediation Training: A Pilot Study
Kiluk BD, Buck MB, Devore KA, Babuscio TA, Nich C, Carroll KM. Performance-Based Contingency Management in Cognitive Remediation Training: A Pilot Study. Journal Of Substance Use And Addiction Treatment 2016, 72: 80-88. PMID: 27590364, PMCID: PMC5154814, DOI: 10.1016/j.jsat.2016.08.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive DysfunctionCognitive RemediationFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePilot ProjectsRewardSubstance-Related DisordersConceptsCognitive remediation trainingRemediation trainingCR trainingCR taskCognitive remediation interventionsTest Part BNeuropsychological assessment batterySUD treatment outcomesNeuropsychological assessment measuresContingency management proceduresFour-week interventionRecall taskDays of abstinenceExecutive functionRemediation interventionsLevel of engagementMild cognitive impairmentAssessment BatteryContingency managementDifferential improvementSession attendanceAssessment measuresCognitive impairmentSubstance usersOutpatient substanceThe effectiveness and cost of clinical supervision for motivational interviewing: A randomized controlled trial
Martino S, Paris M, Añez L, Nich C, Canning-Ball M, Hunkele K, Olmstead TA, Carroll KM. The effectiveness and cost of clinical supervision for motivational interviewing: A randomized controlled trial. Journal Of Substance Use And Addiction Treatment 2016, 68: 11-23. PMID: 27431042, PMCID: PMC4955716, DOI: 10.1016/j.jsat.2016.04.005.Peer-Reviewed Original ResearchConceptsOutpatient substance abuse programsSubstance abuse programsEvidence-based practiceHybrid type 2Substance abstinenceSubstance use differencesType 2CliniciansAbuse programsMotivational interviewingGreater increaseMI strategiesTrialsClinical supervisionMI performanceMIAClient retentionAbstinence
2013
Risk Factors of Violence During a 4-Week Period in a Psychiatric Outpatient Population
Buchanan A, Nich C, Douglas KS, Babuscio T, Easton CJ. Risk Factors of Violence During a 4-Week Period in a Psychiatric Outpatient Population. The Journal Of Nervous And Mental Disease 2013, 201: 1021-1026. PMID: 24284635, DOI: 10.1097/nmd.0000000000000061.Peer-Reviewed Original ResearchDevelopment of the Therapist Empathy Scale
Decker SE, Nich C, Carroll KM, Martino S. Development of the Therapist Empathy Scale. Behavioural And Cognitive Psychotherapy 2013, 42: 339-354. PMID: 23481373, PMCID: PMC3748263, DOI: 10.1017/s1352465813000039.Peer-Reviewed Original ResearchConceptsTherapist empathyEmpathy ScaleMotivational interviewingInternal consistencyDiscriminant validityMI-inconsistent behaviorsConfirmatory factor analysisSingle-factor solutionDifferent psychotherapy approachesInter-rater reliabilityTraining trialsPsychotherapy approachesWatson's workConvergent validityEmpathyExcellent inter-rater reliabilityObserver rating scaleCompetence scoresCriterion validityTES scoresClient outcomesClient sessionsFactor analysisNonsignificant correlationRating Scale
2011
Utilizing Peer Mentorship to Engage High Recidivism Substance-Abusing Patients in Treatment
Tracy K, Burton M, Nich C, Rounsaville B. Utilizing Peer Mentorship to Engage High Recidivism Substance-Abusing Patients in Treatment. The American Journal Of Drug And Alcohol Abuse 2011, 37: 525-531. PMID: 21851202, DOI: 10.3109/00952990.2011.600385.Peer-Reviewed Original ResearchConceptsSubstance-using patientsSubstance abuse patientsSubstance use disordersPrimary outcomeOutpatient treatmentOutpatient appointmentsLack of attendanceTreatment appointmentsHospital settingPast diagnosisUse disordersTreatment attendanceSubstance abusePatientsTreatmentHigh recidivismPeer mentorshipTauAddiction problemsAppointmentsAttendance
2010
Cognitive Function and Treatment Response in a Randomized Clinical Trial of Computer-Based Training in Cognitive-Behavioral Therapy
Carroll KM, Kiluk BD, Nich C, Babuscio TA, Brewer JA, Potenza MN, Ball SA, Martino S, Rounsaville BJ, Lejuez CW. Cognitive Function and Treatment Response in a Randomized Clinical Trial of Computer-Based Training in Cognitive-Behavioral Therapy. Substance Use & Misuse 2010, 46: 23-34. PMID: 21190403, PMCID: PMC3083447, DOI: 10.3109/10826084.2011.521069.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCognitive functionComputer-assisted cognitive behavioral therapyComputer-assisted versionCognitive demandsCognitive functioningRisk takingPoor substanceSubstance usersHomework assignmentsHigh levelsClinical trialsSecondary analysisFunctioningRandomized clinical trialsParticipantsTreatment responseTakingTrainingSessionsSuch patientsInformal discussions in substance abuse treatment sessions with Spanish-speaking clients
Bamatter W, Carroll KM, Añez LM, Paris M, Ball SA, Nich C, Frankforter TL, Suarez-Morales L, Szapocznik J, Martino S. Informal discussions in substance abuse treatment sessions with Spanish-speaking clients. Journal Of Substance Use And Addiction Treatment 2010, 39: 353-363. PMID: 20817381, PMCID: PMC2967664, DOI: 10.1016/j.jsat.2010.07.005.Peer-Reviewed Original ResearchMeSH KeywordsAcculturationAdultFemaleGuideline AdherenceHealth PersonnelHispanic or LatinoHumansInterview, PsychologicalMaleMiddle AgedMotivationMultilingualismPsychotherapySubstance-Related DisordersConceptsMotivational enhancement therapyStandard treatmentDrug Abuse Clinical Trials Network protocolTreatment sessionsSubstance abuse treatment outcomesSignificant inverse correlationHispanic clientsEarly treatment sessionsSession audiotapesTreatment outcomesSubstance abuse treatment sessionsEnhancement therapyClient motivationSubstance useInverse correlationTreatment fidelityNational InstituteTreatmentAdverse consequencesTrialsSessionsClient retentionMonolingual SpanishCoping Strategy Use Following Computerized Cognitive-Behavioral Therapy for Substance Use Disorders
Sugarman DE, Nich C, Carroll KM. Coping Strategy Use Following Computerized Cognitive-Behavioral Therapy for Substance Use Disorders. Psychology Of Addictive Behaviors 2010, 24: 689-695. PMID: 21198228, PMCID: PMC3059590, DOI: 10.1037/a0021584.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedSubstance-Related DisordersTherapy, Computer-AssistedTreatment OutcomeConceptsCognitive behavioral therapyStrategy useObserver ratingsComputerized cognitive behavioral therapyCoping Strategy UseOutpatient substance abuse treatment facilitiesSubstance abuse treatment facilitiesCoping Strategies ScaleRole-play assessmentComputer-based versionSignificant group differencesSubstance use disordersCoping strategiesStrategies ScaleGroup differencesSubstance usersSubstance dependenceUse disordersCBT4CBTDifferential effectsSkillsDrug useDrug-related outcomesParticipantsRatingsRelationship of cognitive function and the acquisition of coping skills in computer assisted treatment for substance use disorders
Kiluk BD, Nich C, Carroll KM. Relationship of cognitive function and the acquisition of coping skills in computer assisted treatment for substance use disorders. Drug And Alcohol Dependence 2010, 114: 169-176. PMID: 21050679, PMCID: PMC3046302, DOI: 10.1016/j.drugalcdep.2010.09.019.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultCognitionCognitive Behavioral TherapyFemaleHumansMaleSubstance-Related DisordersTherapy, Computer-AssistedTreatment OutcomeConceptsCognitive behavioral therapyCognitive functioningCoping skillsBehavioral therapySubstance useCoping skills trainingMeasures of IQSubstance-dependent individualsSignificant indirect effectSubstance use outcomesChronic substance useNeuropsychological measuresNeuropsychological factorsSubstance use disordersComputerized versionHigher IQSkills trainingCognitive functionLower IQLittle previous researchIQDependent individualsPoor functioningUse outcomesCognitive impairment