2011
Utilizing Peer Mentorship to Engage High Recidivism Substance-Abusing Patients in Treatment
Tracy K, Burton M, Nich C, Rounsaville B. Utilizing Peer Mentorship to Engage High Recidivism Substance-Abusing Patients in Treatment. The American Journal Of Drug And Alcohol Abuse 2011, 37: 525-531. PMID: 21851202, DOI: 10.3109/00952990.2011.600385.Peer-Reviewed Original ResearchConceptsSubstance-using patientsSubstance abuse patientsSubstance use disordersPrimary outcomeOutpatient treatmentOutpatient appointmentsLack of attendanceTreatment appointmentsHospital settingPast diagnosisUse disordersTreatment attendanceSubstance abusePatientsTreatmentHigh recidivismPeer mentorshipTauAddiction problemsAppointmentsAttendance
2007
Contingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders
Tracy K, Babuscio T, Nich C, Kiluk B, Carroll KM, Petry NM, Rounsaville BJ. Contingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders. The American Journal Of Drug And Alcohol Abuse 2007, 33: 253-258. PMID: 17497548, PMCID: PMC3390023, DOI: 10.1080/00952990601174931.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcoholismAnalysis of VarianceBehavior TherapyCocaine-Related DisordersConnecticutDiagnosis, Dual (Psychiatry)FemaleHumansIll-Housed PersonsMaleMental DisordersPilot ProjectsReward
2006
Naltrexone and Disulfiram in Patients with Alcohol Dependence and Comorbid Post-Traumatic Stress Disorder
Petrakis IL, Poling J, Levinson C, Nich C, Carroll K, Ralevski E, Rounsaville B. Naltrexone and Disulfiram in Patients with Alcohol Dependence and Comorbid Post-Traumatic Stress Disorder. Biological Psychiatry 2006, 60: 777-783. PMID: 17008146, DOI: 10.1016/j.biopsych.2006.03.074.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderAlcohol dependencePsychiatric symptomsComorbid post-traumatic stress disorderVeterans Administration Outpatient ClinicStress disorderAxis I psychiatric disordersBetter alcohol outcomesDouble-blind randomizationOverall psychiatric symptomsDSM-IV criteriaTreatment of alcoholismOpen randomizationActive medicationAdverse eventsAlcohol use outcomesOutpatient clinicGGT levelsMedication studiesPsychiatric disordersSide effectsNaltrexoneAlcohol cravingDrug AdministrationPlaceboA randomized controlled pilot study of motivational interviewing for patients with psychotic and drug use disorders
Martino S, Carroll KM, Nich C, Rounsaville BJ. A randomized controlled pilot study of motivational interviewing for patients with psychotic and drug use disorders. Addiction 2006, 101: 1479-1492. PMID: 16968350, DOI: 10.1111/j.1360-0443.2006.01554.x.Peer-Reviewed Original ResearchConceptsStandard psychiatric interviewDrug treatment outcomesTreatment outcomesDrug usePilot studyMeasurements Primary outcomeDays of attendancePsychotropic medication adherenceCocaine-using groupPrimary drug useDrug use disordersProportion of participantsPartial hospital programDrug-related disordersImproved treatment outcomesSecondary drug usePrimary outcomeMedication adherencePsychiatric interviewHospital programTrial designUse disordersDual diagnosisMotivational interviewPrimary marijuana
2005
Psychotic Spectrum Disorders and Alcohol Abuse: A Review of Pharmacotherapeutic Strategies and a Report on the Effectiveness of Naltrexone and Disulfiram
Petrakis IL, Nich C, Ralevski E. Psychotic Spectrum Disorders and Alcohol Abuse: A Review of Pharmacotherapeutic Strategies and a Report on the Effectiveness of Naltrexone and Disulfiram. Schizophrenia Bulletin 2005, 32: 644-654. PMID: 16887890, PMCID: PMC2632271, DOI: 10.1093/schbul/sbl010.Peer-Reviewed Original ResearchConceptsPsychotic spectrum disordersPharmacotherapeutic strategiesSchizoaffective disorderBipolar disorderMental illnessAlcohol dependenceBetter alcohol use outcomesEffectiveness of naltrexoneIntensive psychosocial treatmentComorbid mental illnessUse of disulfiramAxis I DisordersSubstance use disordersSpectrum disorderActive medicationAlcohol use outcomesPharmacotherapeutic optionsSignificant morbidityMedication complianceClinical trialsI disordersPsychosocial treatmentsGeneral populationSpecific treatmentAlcohol abuseNaltrexone and Disulfiram in Patients with Alcohol Dependence and Comorbid Psychiatric Disorders
Petrakis IL, Poling J, Levinson C, Nich C, Carroll K, Rounsaville B, Group V. Naltrexone and Disulfiram in Patients with Alcohol Dependence and Comorbid Psychiatric Disorders. Biological Psychiatry 2005, 57: 1128-1137. PMID: 15866552, DOI: 10.1016/j.biopsych.2005.02.016.Peer-Reviewed Original ResearchConceptsPsychiatric disordersAlcohol dependenceVeterans Administration Outpatient ClinicAxis I psychiatric disordersComorbid psychiatric disordersUse of disulfiramTreatment of alcoholismEvent Monitoring SystemAlcohol-dependent individualsActive medicationAdverse eventsSecondary outcomesPrimary outcomeMedication complianceOutpatient clinicSignificant group differencesGGT levelsMedication studiesPsychiatric symptomsAlcohol consumptionNaltrexoneAlcohol cravingDrug AdministrationConsecutive weeksPlacebo
1995
Differential Symptom Reduction in Depressed Cocaine Abusers Treated with Psychotherapy and Pharmacotherapy
CARROLL K, NICH C, ROUNSAVILLE B. Differential Symptom Reduction in Depressed Cocaine Abusers Treated with Psychotherapy and Pharmacotherapy. The Journal Of Nervous And Mental Disease 1995, 183: 251-259. PMID: 7714514, DOI: 10.1097/00005053-199504000-00012.Peer-Reviewed Original ResearchConceptsDepressive symptomsSymptom reductionCocaine abusersTrial of desipramineRelapse prevention treatmentSupportive clinical managementGreater reductionEuthymic subgroupPsychotherapy conditionsDesipramine treatmentEffective antidepressantDepressed subgroupClinical managementCognitive-behavioral treatmentTreatment responsePrevention treatmentCocaine outcomesAmbulatory cocaine abusersDepressive symptomatologyCocaine useCocaine addictsConsecutive abstinence