2011
A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field
Kiluk BD, Sugarman DE, Nich C, Gibbons CJ, Martino S, Rounsaville BJ, Carroll KM. A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field. American Journal Of Psychiatry 2011, 168: 790-799. PMID: 21536689, PMCID: PMC3607199, DOI: 10.1176/appi.ajp.2011.10101443.Peer-Reviewed Original ResearchConceptsComputer-assisted therapyRandomized clinical trialsPsychiatric disordersClinical trialsMethodological qualityEvidence-based behavioral therapiesMethodological Quality IndexPotential adverse eventsEvidence-based therapiesAxis I DisordersAdult psychiatric disordersMethodological quality scoreEvidence-based interventionsAdverse eventsTreat principleRandomized trialsI disordersStudy qualityTreatment exposureTherapyBehavioral therapyCost-effective strategyDisordersTrialsCurrent standard
2009
Mindfulness Training and Stress Reactivity in Substance Abuse: Results from a Randomized, Controlled Stage I Pilot Study
Brewer JA, Sinha R, Chen JA, Michalsen RN, Babuscio TA, Nich C, Grier A, Bergquist KL, Reis DL, Potenza MN, Carroll KM, Rounsaville BJ. Mindfulness Training and Stress Reactivity in Substance Abuse: Results from a Randomized, Controlled Stage I Pilot Study. Substance Use & Addiction Journal 2009, 30: 306-317. PMID: 19904666, PMCID: PMC3045038, DOI: 10.1080/08897070903250241.Peer-Reviewed Original ResearchConceptsSubstance use disordersCognitive behavioral therapyUse disordersDrug useStress reactivityMindfulness trainingCocaine use disorderTreatment satisfactionOutpatient settingStage IStress provocationBehavioral therapySubstance abuseTreatment acceptabilityPilot studySubstance useTreatmentDisordersProvocationPhysiological indicesRandomizedTherapyStudyIndividualsWeeklyA Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users
Carroll KM, Martino S, Ball SA, Nich C, Frankforter T, Anez LM, Paris M, Suarez-Morales L, Szapocznik J, Miller WR, Rosa C, Matthews J, Farentinos C. A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users. Journal Of Consulting And Clinical Psychology 2009, 77: 993-999. PMID: 19803579, PMCID: PMC2792592, DOI: 10.1037/a0016489.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapyEnhancement therapySubstance useSubstance usersRandomized Effectiveness TrialIndividual sessionsCurrent substance useX time interactionTreatment condition interactionCondition x time interactionSubstance use problemsClinical trialsEffectiveness trialTreatment exposureTherapy phaseTreatment retentionTreatment sessionsHispanic adultsTherapyHeterogeneous groupHispanic individualsTime interactionIndividual treatmentTrialsUse problems
2007
Combining Cognitive Behavioral Therapy with Contingency Management for Smoking Cessation in Adolescent Smokers: A Preliminary Comparison of Two Different CBT Formats
Cavallo DA, Cooney JL, Duhig AM, Smith AE, Liss TB, McFetridge AK, Babuscio T, Nich C, Carroll KM, Rounsaville BJ, Krishnan‐Sarin S. Combining Cognitive Behavioral Therapy with Contingency Management for Smoking Cessation in Adolescent Smokers: A Preliminary Comparison of Two Different CBT Formats. American Journal On Addictions 2007, 16: 468-474. PMID: 18058412, PMCID: PMC3677716, DOI: 10.1080/10550490701641173.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyAdolescent smokersContingency managementBehavioral therapySchool-based smoking cessation programBrief behavioral interventionPercent days abstinentCBT conditionWeekly versionCBT groupCBT formatBehavioral interventionsDays abstinentSmoking cessation programWeekly formatTreatment abstinence ratesAbstinence ratesCessation programsMore participantsOptimal formatFour weeksSmokersPilot studyAbstinentTherapySite Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics
Ball SA, Martino S, Nich C, Frankforter TL, Van Horn D, Crits-Christoph P, Woody GE, Obert JL, Farentinos C, Carroll KM. Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics. Journal Of Consulting And Clinical Psychology 2007, 75: 556-567. PMID: 17663610, PMCID: PMC2148493, DOI: 10.1037/0022-006x.75.4.556.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapySubstance useEnhancement therapyBrief intervention conditionsOutpatient substance abuse programsSubstance use reductionDrug abuse clinicsSubstance abuse programsSession audiotapesRandomized trialsClinical trialsMultisite Randomized TrialSustained reductionTherapy phaseDrug usersPrimary alcohol usersAlcohol usersAbuse programsIntervention conditionSignificant increaseTherapyTrialsCAUOutpatientsClinic
2006
The Use of Contingency Management and Motivational/Skills-Building Therapy to Treat Young Adults With Marijuana Dependence
Carroll KM, Easton CJ, Nich C, Hunkele KA, Neavins TM, Sinha R, Ford HL, Vitolo SA, Doebrick CA, Rounsaville BJ. The Use of Contingency Management and Motivational/Skills-Building Therapy to Treat Young Adults With Marijuana Dependence. Journal Of Consulting And Clinical Psychology 2006, 74: 955-966. PMID: 17032099, PMCID: PMC2148500, DOI: 10.1037/0022-006x.74.5.955.Peer-Reviewed Original ResearchConceptsMET/CBTYoung adultsSkill-building interventionsDrug counselingSignificant main effectIndividual drug counselingUrine specimensMarijuana dependenceCriminal justice systemTreatment attendanceCBTMarijuana useContingency managementSession attendanceTreatment retentionJustice systemMain effectIncentives contingentTreatment conditionsAdultsParticipantsAttendanceInterventionContingentTherapy
2004
Millon Clinical Multiaxial Inventory-III Subtypes of Opioid Dependence: Validity and Matching to Behavioral Therapies
Ball SA, Nich C, Rounsaville BJ, Eagan D, Carroll KM. Millon Clinical Multiaxial Inventory-III Subtypes of Opioid Dependence: Validity and Matching to Behavioral Therapies. Journal Of Consulting And Clinical Psychology 2004, 72: 698-711. PMID: 15301655, PMCID: PMC3709250, DOI: 10.1037/0022-006x.72.4.698.Peer-Reviewed Original ResearchConceptsLess symptom improvementOpioid-dependent outpatientsOpioid dependenceSymptom improvementClinical trialsBetter outcomesPredictive validity analysesBehavioral therapyVoucher conditionSubtypesAffective disturbancesIntervention conditionMatching AnalysisPredictive validityCounselingValidity analysisNaltrexoneGroup counselingOutpatientsTherapyTrialsEfficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients: A Randomized Placebo-Controlled Trial
Carroll KM, Fenton LR, Ball SA, Nich C, Frankforter TL, Shi J, Rounsaville BJ. Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients: A Randomized Placebo-Controlled Trial. JAMA Psychiatry 2004, 61: 264-272. PMID: 14993114, PMCID: PMC3675448, DOI: 10.1001/archpsyc.61.3.264.Peer-Reviewed Original ResearchConceptsCocaine useGeneral populationCocaine dependenceEfficacy of disulfiramUrine toxicology screenOutpatient substance abuse treatment programsBehavior therapyConcurrent alcohol useSubstance abuse treatment programsCurrent cocaine dependenceCognitive behavior therapyDisulfiram useRandomized PlaceboDisulfiram therapyMedication complianceToxicology screenIdentical capsulesEffective therapyPlaceboCocaine-dependent individualsSelf-reported frequencyPromising treatmentPlacebo conditionInterpersonal psychotherapyTherapy
2002
Contingency Management to Enhance Naltrexone Treatment of Opioid Dependence: A Randomized Clinical Trial of Reinforcement Magnitude
Carroll KM, Sinha R, Nich C, Babuscio T, Rounsaville BJ. Contingency Management to Enhance Naltrexone Treatment of Opioid Dependence: A Randomized Clinical Trial of Reinforcement Magnitude. Experimental And Clinical Psychopharmacology 2002, 10: 54-63. PMID: 11866252, DOI: 10.1037/1064-1297.10.1.54.Peer-Reviewed Original ResearchConceptsNaltrexone treatmentContingency managementOpioid-dependent individualsSignificant reductionReinforcement magnitudeOpioid useAvailable pharmacotherapiesNaltrexone maintenanceOpioid dependenceClinical trialsCM groupBehavioral therapyNaltrexoneTreatmentCM conditionRelative benefitsParticipantsPharmacotherapyTherapyTrialsWeeks
2001
Targeting Behavioral Therapies to Enhance Naltrexone Treatment of Opioid Dependence: Efficacy of Contingency Management and Significant Other Involvement
Carroll KM, Ball SA, Nich C, O'Connor PG, Eagan DA, Frankforter TL, Triffleman EG, Shi J, Rounsaville BJ. Targeting Behavioral Therapies to Enhance Naltrexone Treatment of Opioid Dependence: Efficacy of Contingency Management and Significant Other Involvement. JAMA Psychiatry 2001, 58: 755-761. PMID: 11483141, PMCID: PMC3651594, DOI: 10.1001/archpsyc.58.8.755.Peer-Reviewed Original ResearchConceptsDrug-free urine specimensNaltrexone treatmentFamily counseling sessionsContingency managementOpioid dependenceTreatment retentionUrine specimensBehavioral therapyOpioid-dependent individualsCounseling sessionsDrug use outcomesSubstance abuse outcomesNaltrexone complianceNaltrexone therapyOpioid useAvailable pharmacotherapiesMedication complianceSpecific pharmacotherapySignificant improvementTherapyUse outcomesAbuse outcomesPrincipal outcomePharmacotherapyTreatmentPerspective is everything: the predictive validity of six working alliance instruments.
Fenton LR, Cecero JJ, Nich C, Frankforter TL, Carroll KM. Perspective is everything: the predictive validity of six working alliance instruments. American Journal Of Psychotherapy 2001, 10: 262-8. PMID: 11696653, PMCID: PMC3330662.Peer-Reviewed Original ResearchConceptsObserver-rated instrumentsAlliance ScaleVanderbilt Therapeutic Alliance ScaleManual-guided therapiesTwelve-step facilitationObjective outcome measuresCalifornia Psychotherapy Alliance ScalesPredictive validityTherapeutic Alliance ScaleCognitive behavioral therapyWorking Alliance InventoryClinical trialsOutcome measuresAlliance instrumentsRating ScaleSubstance useTherapist-rated measureTherapeutic allianceAlliance InventoryTherapyOutcomes