2024
T166 Treatment Outcomes From Computerized CBT for Substance Use Disorders Among People With Criminal Justice Involvement
Loya J, Babuscio T, Nich C, Kiluk B. T166 Treatment Outcomes From Computerized CBT for Substance Use Disorders Among People With Criminal Justice Involvement. Drug And Alcohol Dependence 2024, 260: 110615. DOI: 10.1016/j.drugalcdep.2023.110615.Peer-Reviewed Original Research
2020
Short- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders
Roos CR, Carroll KM, Nich C, Frankforter T, Kiluk BD. Short- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders. Drug And Alcohol Dependence 2020, 212: 108044. PMID: 32422538, PMCID: PMC7293942, DOI: 10.1016/j.drugalcdep.2020.108044.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyComputerized cognitive behavioral therapyPerson cognitive-behavioural therapySubstance use disordersMediation effectAlcohol use disorderComputer-delivered cognitive behavioural therapyUse disordersSame mediation effectSubstance-related copingCoping Strategies ScaleSignificant mediation effectMechanisms of changeMediational modelCoping skillsStrategies ScaleCBT4CBTStatistical mediatorCopingDrug use disordersSubstance useHeavy drinkingDisordersLong-term changesLong-term increase
2019
Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder
DeVito EE, Carroll KM, Babuscio T, Nich C, Sofuoglu M. Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder. Journal Of Substance Use And Addiction Treatment 2019, 107: 29-37. PMID: 31757262, PMCID: PMC6918721, DOI: 10.1016/j.jsat.2019.08.009.Peer-Reviewed Original ResearchConceptsCocaine use disorderSignificant treatment group differencesUse disordersEfficacy of galantamineTreatment-seeking cocaine usersCurrent cocaine use disordersGroup differencesCocaine use outcomesSample of individualsTreatment group differencesComorbid opioid use disorderMethadone-maintained individualsMemory capacityAbstinent individualsCocaine useCognitive improvementCognitive outcomesCocaine use reductionCognitive functionUse outcomesCocaine usersGalantamine groupIndividualsDisordersInitial promise
2018
Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder
Carroll KM, Nich C, Frankforter TL, Yip SW, Kiluk BD, DeVito EE, Sofuoglu M. Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder. Drug And Alcohol Dependence 2018, 192: 264-270. PMID: 30300800, PMCID: PMC6203294, DOI: 10.1016/j.drugalcdep.2018.08.019.Peer-Reviewed Original ResearchConceptsOpioid use disorderOral naltrexoneUse disordersAffective symptomsVoucher-based contingency managementDysphoric symptomsAffective distressOral naltrexone treatmentMultiple baseline characteristicsBaseline characteristicsNaltrexone treatmentHigh riskNaltrexoneSomatic symptomsSymptomsContingency managementTreatmentHigh rateDistressSubstantial evidenceTrialsTheoretical benefitsDisordersAffective discomfortParticipantsCulturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial.
Paris M, Silva M, Añez-Nava L, Jaramillo Y, Kiluk BD, Gordon MA, Nich C, Frankforter T, Devore K, Ball SA, Carroll KM. Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial. American Journal Of Public Health 2018, 108: 1535-1542. PMID: 30252519, PMCID: PMC6187780, DOI: 10.2105/ajph.2018.304571.Peer-Reviewed Original ResearchConceptsSubstance use disordersCognitive-behavioral treatmentUse disordersSubstance use outcomesClinical trialsWeb-based cognitive behavioral therapyCurrent substance use disorderUse outcomesRandomized clinical trialsStandard outpatient treatmentEvidence-based treatmentsCognitive behavioral therapyPrimary outcomeStandard treatmentOutpatient treatmentStandard outpatientTreatment completionHealth disparitiesBehavioral therapyBehavioral treatmentAddiction treatmentTreatment-seeking individualsGreater reductionTreatmentDisorders
2016
Alexithymia and Addiction: A Review and Preliminary Data Suggesting Neurobiological Links to Reward/Loss Processing
Morie KP, Yip SW, Nich C, Hunkele K, Carroll KM, Potenza MN. Alexithymia and Addiction: A Review and Preliminary Data Suggesting Neurobiological Links to Reward/Loss Processing. Current Addiction Reports 2016, 3: 239-248. PMID: 27695665, PMCID: PMC5040368, DOI: 10.1007/s40429-016-0097-8.Peer-Reviewed Original ResearchReward/loss processingSubstance use disordersLoss processingRole of alexithymiaPreliminary fMRI dataUse disordersCocaine-dependent individualsEmotional awarenessNeural correlatesReward anticipationNeurobiological correlatesAlexithymiaNeurobiological linkFMRI dataSubstance useSubstance dependenceCocaine dependenceAddictionCorrelatesIndividualsDisordersProcessingAnticipationImpairment
2015
The acquisition of coping skills from computerized cognitive behavioral therapy for substance use disorders: It's all where you start
Kiluk B, DeVito E, Buck M, Nich C, Carroll K. The acquisition of coping skills from computerized cognitive behavioral therapy for substance use disorders: It's all where you start. Drug And Alcohol Dependence 2015, 156: e110. DOI: 10.1016/j.drugalcdep.2015.07.305.Commentaries, Editorials and Letters
2011
A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field
Kiluk BD, Sugarman DE, Nich C, Gibbons CJ, Martino S, Rounsaville BJ, Carroll KM. A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field. American Journal Of Psychiatry 2011, 168: 790-799. PMID: 21536689, PMCID: PMC3607199, DOI: 10.1176/appi.ajp.2011.10101443.Peer-Reviewed Original ResearchConceptsComputer-assisted therapyRandomized clinical trialsPsychiatric disordersClinical trialsMethodological qualityEvidence-based behavioral therapiesMethodological Quality IndexPotential adverse eventsEvidence-based therapiesAxis I DisordersAdult psychiatric disordersMethodological quality scoreEvidence-based interventionsAdverse eventsTreat principleRandomized trialsI disordersStudy qualityTreatment exposureTherapyBehavioral therapyCost-effective strategyDisordersTrialsCurrent standard
2009
Mindfulness Training and Stress Reactivity in Substance Abuse: Results from a Randomized, Controlled Stage I Pilot Study
Brewer JA, Sinha R, Chen JA, Michalsen RN, Babuscio TA, Nich C, Grier A, Bergquist KL, Reis DL, Potenza MN, Carroll KM, Rounsaville BJ. Mindfulness Training and Stress Reactivity in Substance Abuse: Results from a Randomized, Controlled Stage I Pilot Study. Substance Use & Addiction Journal 2009, 30: 306-317. PMID: 19904666, PMCID: PMC3045038, DOI: 10.1080/08897070903250241.Peer-Reviewed Original ResearchConceptsSubstance use disordersCognitive behavioral therapyUse disordersDrug useStress reactivityMindfulness trainingCocaine use disorderTreatment satisfactionOutpatient settingStage IStress provocationBehavioral therapySubstance abuseTreatment acceptabilityPilot studySubstance useTreatmentDisordersProvocationPhysiological indicesRandomizedTherapyStudyIndividualsWeekly
2007
The Impact of Personality Disorders on Alcohol‐Use Outcomes in a Pharmacotherapy Trial for Alcohol Dependence and Comorbid Axis I Disorders
Ralevski E, Ball S, Nich C, Limoncelli D, Petrakis I. The Impact of Personality Disorders on Alcohol‐Use Outcomes in a Pharmacotherapy Trial for Alcohol Dependence and Comorbid Axis I Disorders. American Journal On Addictions 2007, 16: 443-449. PMID: 18058408, DOI: 10.1080/10550490701643336.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DeterrentsAlcoholismAntisocial Personality DisorderBehavior, AddictiveBorderline Personality DisorderComorbidityDiagnostic and Statistical Manual of Mental DisordersDisulfiramFemaleHumansMaleMental DisordersMiddle AgedNaltrexoneNarcotic AntagonistsPatient CompliancePersonality DisordersPlacebosPsychiatric Status Rating ScalesTreatment OutcomeConceptsBorderline personality disorderAxis I DisordersAlcohol dependenceAlcohol use outcomesPersonality disorderI disordersAxis IComorbid Axis I disordersContext of pharmacotherapyAxis II disordersMajor Axis IMedication trialsPharmacotherapy trialsPoor responseOutcome measuresPatientsNaltrexoneAlcohol useDiagnosisUse outcomesDiagnosis of antisocialDisordersDisulfiramOutcomesASPDContingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders
Tracy K, Babuscio T, Nich C, Kiluk B, Carroll KM, Petry NM, Rounsaville BJ. Contingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders. The American Journal Of Drug And Alcohol Abuse 2007, 33: 253-258. PMID: 17497548, PMCID: PMC3390023, DOI: 10.1080/00952990601174931.Peer-Reviewed Original Research