2005
Psychotic Spectrum Disorders and Alcohol Abuse: A Review of Pharmacotherapeutic Strategies and a Report on the Effectiveness of Naltrexone and Disulfiram
Petrakis IL, Nich C, Ralevski E. Psychotic Spectrum Disorders and Alcohol Abuse: A Review of Pharmacotherapeutic Strategies and a Report on the Effectiveness of Naltrexone and Disulfiram. Schizophrenia Bulletin 2005, 32: 644-654. PMID: 16887890, PMCID: PMC2632271, DOI: 10.1093/schbul/sbl010.Peer-Reviewed Original ResearchConceptsPsychotic spectrum disordersPharmacotherapeutic strategiesSchizoaffective disorderBipolar disorderMental illnessAlcohol dependenceBetter alcohol use outcomesEffectiveness of naltrexoneIntensive psychosocial treatmentComorbid mental illnessUse of disulfiramAxis I DisordersSubstance use disordersSpectrum disorderActive medicationAlcohol use outcomesPharmacotherapeutic optionsSignificant morbidityMedication complianceClinical trialsI disordersPsychosocial treatmentsGeneral populationSpecific treatmentAlcohol abuse
2000
Disulfiram treatment for cocaine dependence in methadone‐maintained opioid addicts
Petrakis IL, Carroll KM, Nich C, Gordon LT, McCance-Katz EF, Frankforter T, Rounsaville BJ. Disulfiram treatment for cocaine dependence in methadone‐maintained opioid addicts. Addiction 2000, 95: 219-228. PMID: 10723850, DOI: 10.1046/j.1360-0443.2000.9522198.x.Peer-Reviewed Original ResearchConceptsCo-morbid alcohol abuseOpioid addictsAlcohol abuseCocaine abuseCocaine dependenceAlcohol useEfficacy of disulfiramExcess of dopamineUrine toxicology screenPlacebo-controlled trialPrimary outcome measureMethadone maintenance treatmentOpioid-dependent subjectsRe-uptake inhibitorsMethadone maintenance clinicsSynthesis of norepinephrineFrequency of cocaineStudy medicationToxicology screenComorbid alcoholMaintenance treatmentPoor prognosisEffective pharmacotherapyDisulfiram treatmentMaintenance clinics
1998
Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram
Carroll KM, Nich C, Ball SA, McCance E, Rounsavile BJ. Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram. Addiction 1998, 93: 713-727. PMID: 9692270, DOI: 10.1046/j.1360-0443.1998.9357137.x.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentAlcohol useClinical managementCocaine useConcurrent alcohol abuseDrug use disordersTreatment of cocaineCo-morbid disordersPromising treatment strategySubstance abuse treatment centersTreatment-seeking cocaine abusersUrine toxicologyDrug-dependent individualsContinuous abstinenceDisulfiram treatmentStep FacilitationTreatment strategiesCocaine-dependent individualsAlcohol abuseAlcohol abusersUse disordersTreatment centersSupportive psychotherapyAlcohol dependenceActive psychotherapy