2024
Contribution of climate change to the spatial expansion of West Nile virus in Europe
Erazo D, Grant L, Ghisbain G, Marini G, Colón-González F, Wint W, Rizzoli A, Van Bortel W, Vogels C, Grubaugh N, Mengel M, Frieler K, Thiery W, Dellicour S. Contribution of climate change to the spatial expansion of West Nile virus in Europe. Nature Communications 2024, 15: 1196. PMID: 38331945, PMCID: PMC10853512, DOI: 10.1038/s41467-024-45290-3.Peer-Reviewed Original ResearchConceptsWest Nile virusEcological niche modelsExpansion of West Nile virusClimate changeWNV circulationNiche modelsNile virusMosquito-borne pathogensEffects of climate changeHuman population changeSpatial expansionContributions of climate changeWest Nile virus circulationEnvironmental changesPublic health threatHuman populationLand-useHuman influencePotential driversRisk of exposureLong-term trendsPopulation densityPopulation changeHealth threatClimate
2019
Twenty years of West Nile virus spread and evolution in the Americas visualized by Nextstrain
Hadfield J, Brito AF, Swetnam DM, Vogels CBF, Tokarz RE, Andersen KG, Smith RC, Bedford T, Grubaugh ND. Twenty years of West Nile virus spread and evolution in the Americas visualized by Nextstrain. PLOS Pathogens 2019, 15: e1008042. PMID: 31671157, PMCID: PMC6822705, DOI: 10.1371/journal.ppat.1008042.Peer-Reviewed Original ResearchEffect of overwintering on survival and vector competence of the West Nile virus vector Culex pipiens
Koenraadt CJM, Möhlmann TWR, Verhulst NO, Spitzen J, Vogels CBF. Effect of overwintering on survival and vector competence of the West Nile virus vector Culex pipiens. Parasites & Vectors 2019, 12: 147. PMID: 30917854, PMCID: PMC6437999, DOI: 10.1186/s13071-019-3400-4.Peer-Reviewed Original ResearchConceptsVector competencePipiens mosquitoesBiotype pipiensMosquito-borne virusLaboratory-reared CxReal-time PCROlder ageConclusionsThis studyCulex pipiens mosquitoesBiotype compositionLaboratory-reared mosquitoesNile virusLaboratory-reared femalesSurvivalMonthsPipiens biotypesTwo-thirdsCulex pipiensWNV transmissionWest Nile virus vector Culex pipiensBiotype molestusPipiens femalesWNVMosquitoesSpecies Cx
2017
Virus interferes with host-seeking behaviour of mosquito
Vogels CBF, Fros JJ, Pijlman GP, van Loon JJA, Gort G, Koenraadt CJM. Virus interferes with host-seeking behaviour of mosquito. Journal Of Experimental Biology 2017, 220: 3598-3603. PMID: 28978641, DOI: 10.1242/jeb.164186.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBirdsCulexFemaleHost-Seeking BehaviorInsect VectorsOlfactometrySensillaWest Nile virusVector competence of northern and southern European Culex pipiens pipiens mosquitoes for West Nile virus across a gradient of temperatures
Vogels CBF, Göertz GP, Pijlman GP, Koenraadt CJM. Vector competence of northern and southern European Culex pipiens pipiens mosquitoes for West Nile virus across a gradient of temperatures. Medical And Veterinary Entomology 2017, 31: 358-364. PMID: 28752627, DOI: 10.1111/mve.12251.Peer-Reviewed Original ResearchModelling West Nile virus transmission risk in Europe: effect of temperature and mosquito biotypes on the basic reproduction number
Vogels CBF, Hartemink N, Koenraadt CJM. Modelling West Nile virus transmission risk in Europe: effect of temperature and mosquito biotypes on the basic reproduction number. Scientific Reports 2017, 7: 5022. PMID: 28694450, PMCID: PMC5504010, DOI: 10.1038/s41598-017-05185-4.Peer-Reviewed Original ResearchVector competence of European mosquitoes for West Nile virus
Vogels CB, Göertz GP, Pijlman GP, Koenraadt CJ. Vector competence of European mosquitoes for West Nile virus. Emerging Microbes & Infections 2017, 6: 1-13. PMID: 29116220, PMCID: PMC5717085, DOI: 10.1038/emi.2017.82.Peer-Reviewed Original Research
2016
Latitudinal Diversity of Culex pipiens Biotypes and Hybrids in Farm, Peri-Urban, and Wetland Habitats in Europe
Vogels CB, Möhlmann TW, Melsen D, Favia G, Wennergren U, Koenraadt CJ. Latitudinal Diversity of Culex pipiens Biotypes and Hybrids in Farm, Peri-Urban, and Wetland Habitats in Europe. PLOS ONE 2016, 11: e0166959. PMID: 27870890, PMCID: PMC5117740, DOI: 10.1371/journal.pone.0166959.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChimeraCulexDisease OutbreaksEuropeRisk AssessmentUrban RenewalWest Nile FeverWest Nile virusWetlandsConceptsHabitat typesPipiens mosquitoesPipiens biotypesPopulation dynamics studiesMosquito Magnet Liberty Plus trapsWest Nile virusCulex pipiens mosquitoesLatitudinal diversityWetland habitatsCulex pipiens biotypesReal-time PCRRelative abundanceBiotype levelSpecies CxBiotypesSurveillance trapsPipiensMolestusWNV outbreaksHybridsNoncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes
Göertz GP, Fros JJ, Miesen P, Vogels CB, van der Bent ML, Geertsema C, Koenraadt CJ, van Rij RP, van Oers MM, Pijlman GP. Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes. Journal Of Virology 2016, 90: 10145-10159. PMID: 27581979, PMCID: PMC5105652, DOI: 10.1128/jvi.00930-16.Peer-Reviewed Original ResearchConceptsSubgenomic flavivirus RNARNA interference machineryCulex pipiens mosquitoesWest Nile virusInterference machinerySfRNA productionPipiens mosquitoesBiological functionsUntranslated regionNile virusPivotal biological functionsIntrathoracic injectionWild-type WNVRNA deep sequencingKey biological functionsBlood mealFlavivirus RNAMosquito cell linesFlavivirus West Nile virusViral genomic RNAMosquito midgut barrierMutant West Nile virusTick-borne flavivirusesWNV-infected mosquitoesMammalian cellsVector competence of northern European Culex pipiens biotypes and hybrids for West Nile virus is differentially affected by temperature
Vogels CB, Fros JJ, Göertz GP, Pijlman GP, Koenraadt CJ. Vector competence of northern European Culex pipiens biotypes and hybrids for West Nile virus is differentially affected by temperature. Parasites & Vectors 2016, 9: 393. PMID: 27388451, PMCID: PMC4937539, DOI: 10.1186/s13071-016-1677-0.Peer-Reviewed Original ResearchConceptsWest Nile virusVector competence studiesVector competenceMosquito midgut barrierNile virusInfectious blood mealCompetence studiesPipiens biotypesCulex pipiens biotypesViral titersSaliva samplesMidgut barrierInfectionBiotype pipiensBlood mealWNV presenceTitersOverall transmission rateVirusMosquitoesPipiens mosquitoesBiotype levelRisk assessmentPipiensMethodsWe
2015
Winter Activity and Aboveground Hybridization Between the Two Biotypes of the West Nile Virus Vector Culex pipiens
Vogels CB, van de Peppel LJ, van Vliet AJ, Westenberg M, Ibañez-Justicia A, Stroo A, Buijs JA, Visser TM, Koenraadt CJ. Winter Activity and Aboveground Hybridization Between the Two Biotypes of the West Nile Virus Vector Culex pipiens. Vector-Borne And Zoonotic Diseases 2015, 15: 619-626. PMID: 26394124, DOI: 10.1089/vbz.2015.1820.Peer-Reviewed Original ResearchWest Nile Virus: High Transmission Rate in North-Western European Mosquitoes Indicates Its Epidemic Potential and Warrants Increased Surveillance
Fros JJ, Geertsema C, Vogels CB, Roosjen PP, Failloux AB, Vlak JM, Koenraadt CJ, Takken W, Pijlman GP. West Nile Virus: High Transmission Rate in North-Western European Mosquitoes Indicates Its Epidemic Potential and Warrants Increased Surveillance. PLOS Neglected Tropical Diseases 2015, 9: e0003956. PMID: 26225555, PMCID: PMC4520649, DOI: 10.1371/journal.pntd.0003956.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineCulexEpidemicsEuropeHumansPopulation SurveillanceSalivaTemperatureWest Nile FeverWest Nile virusConceptsWest Nile virusEpidemic potentialLineage 1 West Nile VirusInfectious blood mealFurther epidemic spreadLineage 2 West Nile virusNeuroinvasive diseaseIntrathoracic injectionEuropean mosquitoesPathogenic flavivirusesInfection rateVirus activityLarge outbreakVirus disseminationWNV infection ratesNile virusWNV activityWNV lineagesBlood mealVector competenceInfectionCulex pipiens mosquitoesWNV transmissionEpidemic spreadDisease-free regions