2020
A satellite repeat-derived piRNA controls embryonic development of Aedes
Halbach R, Miesen P, Joosten J, Taşköprü E, Rondeel I, Pennings B, Vogels C, Merkling S, Koenraadt C, Lambrechts L, van Rij R. A satellite repeat-derived piRNA controls embryonic development of Aedes. Nature 2020, 580: 274-277. PMID: 32269344, PMCID: PMC7145458, DOI: 10.1038/s41586-020-2159-2.Peer-Reviewed Original ResearchConceptsPIWI-interacting RNAsSatellite repeatsEmbryonic developmentGene expressionAbundant piwi-interacting RNAsLocal chromatin structureGlobal gene expressionTandem repeat elementsSequence-specific geneMosquito Aedes aegyptiPiRNA productionEukaryotic chromosomesChromatin structureEuchromatic regionsPiRNA sequencesMosquito biologyRepeat elementsDevelopmental arrestRepeatsDiverse classAedes aegyptiGenesTranscriptsCentral functionExpression
2018
Vector competence of biting midges and mosquitoes for Shuni virus
Möhlmann TWR, Oymans J, Schreur P, Koenraadt CJM, Kortekaas J, Vogels CBF. Vector competence of biting midges and mosquitoes for Shuni virus. PLOS Neglected Tropical Diseases 2018, 12: e0006993. PMID: 30532189, PMCID: PMC6285265, DOI: 10.1371/journal.pntd.0006993.Peer-Reviewed Original ResearchConceptsShuni virusInfection rateInfectious blood mealEvidence of transmissionHigher infection rateFebrile childrenCongenital malformationsNeurological diseasesPotential transmissionPotential involvementHigh pathogenicityZoonotic potentialSimbu serogroupBlood mealVector competenceVirusMosquitoesRiskBroad tropismArthropod vectorsAedes aegyptiAnimalsCulex pipiens pipiensFurther researchFuture epizootics