2006
The role of the ventral prefrontal cortex in mood disorders
Fredericks C, Kalmar J, Blumberg H. The role of the ventral prefrontal cortex in mood disorders. 2006, 545-578. DOI: 10.1093/acprof:oso/9780198565741.003.0021.Peer-Reviewed Original ResearchVentral prefrontal cortexMood disordersPrefrontal cortexPregenual anterior cingulateLateral orbitofrontal cortexRostral frontal cortexMajor depressionFrontal cortexAnterior cingulateBipolar disorderOrbitofrontal cortexBrain structuresCortexDisordersMultiple studiesSpecific subregionsNeural systemsSignificant connectivityNeuropathophysiologyCingulate
2005
Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder
Blumberg HP, Fredericks C, Wang F, Kalmar JH, Spencer L, Papademetris X, Pittman B, Martin A, Peterson BS, Fulbright RK, Krystal JH. Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder. Bipolar Disorders 2005, 7: 570-576. PMID: 16403182, PMCID: PMC2291299, DOI: 10.1111/j.1399-5618.2005.00264.x.Peer-Reviewed Original ResearchConceptsAmygdala volumeBipolar disorderYoung adultsAmygdala volume abnormalitiesTotal brain volumeHigh-resolution magnetic resonancePreliminary evidenceSubjects longitudinal designPersistent abnormalitiesMixed-model statistical analysisBD IVolume abnormalitiesHealthy comparison participantsBrain volumeHealthy participantsAbnormalitiesAdultsAdolescentsComparison participantsAmygdalaDevelopmental epochsDisordersLongitudinal designParticipantsMagnetic resonance