2023
Cognitive training for children with ADHD: composite cognitive score outcome in a randomized controlled trial
Bikic A, Dalsgaard S, Pittman B, Leckman J, Wexler B. Cognitive training for children with ADHD: composite cognitive score outcome in a randomized controlled trial. Nordic Journal Of Psychiatry 2023, 78: 87-91. PMID: 37905332, DOI: 10.1080/08039488.2023.2270954.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityChildCognitionCognitive TrainingHumansTreatment OutcomeConceptsAttention-deficit/hyperactivity disorderCognitive trainingDeficit/hyperactivity disorderComposite cognition scoreSessions of trainingCognitive functioningHyperactivity disorderCognitive improvementCognition scoresTraining sessionsMixed resultsFrequency of trainingTrainingChildrenSessionsIntervention groupCognitionInterventionFunctioningPost Hoc AnalysisScore outcomesControl groupPrevious studiesDisordersOutcomesUsing micro-cognition biomarkers of neurosystem dysfunction to redefine ADHD subtypes: A scalable digital path to diagnosis based on brain function
Wexler B, Kish R. Using micro-cognition biomarkers of neurosystem dysfunction to redefine ADHD subtypes: A scalable digital path to diagnosis based on brain function. Psychiatry Research 2023, 326: 115348. PMID: 37494880, PMCID: PMC10517859, DOI: 10.1016/j.psychres.2023.115348.Peer-Reviewed Original ResearchConceptsPoor response inhibitionResponse inhibitionSymptom-based diagnosisGO/NOGO testMarked performance decrementsNew treatment developmentTD childrenADHD childrenADHD subtypesPerformance decrementsInconsistent attentionAbstract categoriesTreatment developmentNatural categoriesBrain functionADHDDifferent neuropathologiesChildren 6Individual patientsTreatment selection
2020
An integrated program of computer-presented and physical cognitive training exercises for children with attention-deficit/hyperactivity disorder
Wexler BE, Vitulano LA, Moore C, Katsovich L, Smith SD, Rush C, Grantz H, Dong J, Leckman JF. An integrated program of computer-presented and physical cognitive training exercises for children with attention-deficit/hyperactivity disorder. Psychological Medicine 2020, 51: 1524-1535. PMID: 32090720, DOI: 10.1017/s0033291720000288.Peer-Reviewed Original ResearchMeSH KeywordsAttention Deficit Disorder with HyperactivityChildCognitionCognition DisordersCognitive Behavioral TherapyComputersCross-Over StudiesExecutive FunctionExerciseFemaleHumansImpulsive BehaviorMaleMemory, Short-TermConceptsAttention deficit hyperactivity disorderExperimental medicine approachTAU groupMedicine approachHyperactivity disorderWeeks of treatmentCombined subtypeDiagnosis of ADHDClinical trial designHyperactive-impulsive subtypeAttention-deficit/hyperactivity disorderCross-over designDeficit hyperactivity disorderClinical improvementClinical symptomsRandomized crossCognitive dysfunctionCT groupPathophysiological heterogeneityCONSORT recommendationsTrial designResponse rateChange scoresSubtypesTargeted pathology
2019
Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD
Smith SD, Crowley MJ, Ferrey A, Ramsey K, Wexler BE, Leckman JF, Sukhodolsky DG. Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD. Psychiatry Research 2019, 278: 248-257. PMID: 31233935, PMCID: PMC6637759, DOI: 10.1016/j.psychres.2019.06.021.Peer-Reviewed Original ResearchMeSH KeywordsAttentionAttention Deficit Disorder with HyperactivityBehavior TherapyBrainChildCognitive Behavioral TherapyCombined Modality TherapyElectroencephalographyEvoked PotentialsExerciseExercise TherapyFemaleHumansMalePilot ProjectsReaction TimeTreatment OutcomeConceptsBehavioral measuresAttentional controlIntegrated brainGo/No-Go taskGo-P3 latencySlower reaction timesSocial interventionsRobust treatment effectAttentional systemADHD groupERP measuresDifference waveP3 latencyBrain activityADHDTAU groupEEG proceduresHealthy controlsHC groupReaction timeReplication purposesERPTreatment effectsChildrenSecondary goal
1993
Effects of Emotion on Perceptual Asymmetry in Adolescent Inpatients with Attention-deficit Hyperactivity Disorder
BECKER D, DOANE J, WEXLER B. Effects of Emotion on Perceptual Asymmetry in Adolescent Inpatients with Attention-deficit Hyperactivity Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 1993, 32: 318-323. PMID: 8444760, DOI: 10.1097/00004583-199303000-00012.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultArousalAttentionAttention Deficit Disorder with HyperactivityDominance, CerebralEmotionsFemaleHospitalizationHumansMaleProhibitinsReinforcement, PsychologySocializationSpeech PerceptionConceptsAttention-deficit hyperactivity disorderRight ear advantageAdolescent inpatientsPerceptual asymmetryHyperactivity disorderPositive wordsAttention-deficit hyperactivity disorder groupEmotional conditionsLower right ear advantageRight-ear advantage scoreEffects of emotionPositive emotional toneDichotic Words TestPositive emotional conditionFunctioning of adolescentsEmotional stimuliAttention-DeficitHemisphere functionNegative wordsStimulus pairsDysfunction hypothesisWord TestBehavioral difficultiesEar advantageEmotional tone