2015
Trait-level temporal lobe hypoactivation to social exclusion in unaffected siblings of children and adolescents with autism spectrum disorders
Bolling DZ, Pelphrey KA, Vander Wyk B. Trait-level temporal lobe hypoactivation to social exclusion in unaffected siblings of children and adolescents with autism spectrum disorders. Developmental Cognitive Neuroscience 2015, 13: 75-83. PMID: 26011751, PMCID: PMC4470300, DOI: 10.1016/j.dcn.2015.04.007.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderPosterior superior temporal sulcusUnaffected siblingsAtypical neural processingSocial exclusionFunctional magnetic resonance imagingSuperior temporal sulcusAbnormal neural responsesAnterior temporoparietal junctionAnterior cingulate cortexEmotion processingTemporoparietal junctionNegative affectTemporal sulcusNeural processingBrain responsesNeural endophenotypesNeural responsesNeural activationCingulate cortexNeural circuitrySocial experienceASD probandsPowerful feelings
2014
Altered brain connectivity in sagittal craniosynostosis.
Beckett JS, Brooks ED, Lacadie C, Wyk B, Jou RJ, Steinbacher DM, Constable RT, Pelphrey KA, Persing JA. Altered brain connectivity in sagittal craniosynostosis. Journal Of Neurosurgery Pediatrics 2014, 13: 690-8. PMID: 24745341, DOI: 10.3171/2014.3.peds13516.Peer-Reviewed Original ResearchConceptsDiffusion tensor imagingPosterior cingulate cortexCingulate cortexSagittal nonsyndromic craniosynostosisPrefrontal cortexRight posterior cingulate cortexBrodmann area 8Functional connectivity differencesRight middle frontal gyrusWhite matter alterationsAnterior cingulate cortexBrodmann area 7Left ventromedial prefrontal cortexAltered brain connectivityResting-state functional connectivity MRI dataMiddle frontal gyrusRight supramarginal gyrusDefault mode networkIntrinsic connectivity analysesSignificant group differencesAdolescent patientsAltered connectivityNeurocognitive morbidityHigh prevalenceRight parahippocampus
2012
Action representation in the superior temporal sulcus in children and adults: An fMRI study
Vander Wyk B, Voos A, Pelphrey KA. Action representation in the superior temporal sulcus in children and adults: An fMRI study. Developmental Cognitive Neuroscience 2012, 2: 409-416. PMID: 22727762, PMCID: PMC3431200, DOI: 10.1016/j.dcn.2012.04.004.Peer-Reviewed Original ResearchConceptsSuperior temporal sulcusFunctional magnetic resonance imaging paradigmCongruent trialsTemporal sulcusPosterior superior temporal sulcusIncongruent actionsBiological motionSTS regionFMRI studyAction representationNegative regardImaging paradigmOrder informationHigher-order informationDevelopmental changesOlder childrenChildrenSulcusAdultsTrialsCongruencyRepresentationCongruentPerceptionObjects
2011
Research Review: Constraining heterogeneity: the social brain and its development in autism spectrum disorder
Pelphrey KA, Shultz S, Hudac CM, Vander Wyk B. Research Review: Constraining heterogeneity: the social brain and its development in autism spectrum disorder. Journal Of Child Psychology And Psychiatry 2011, 52: 631-644. PMID: 21244421, PMCID: PMC3096715, DOI: 10.1111/j.1469-7610.2010.02349.x.Peer-Reviewed Original ResearchMeSH KeywordsAmygdalaBrainBrain MappingChildChild Development Disorders, PervasiveEmotionsEndophenotypesFacial ExpressionFemaleGenetic Predisposition to DiseaseHumansIntentionMagnetic Resonance ImagingMaleNerve NetPattern Recognition, VisualPersonal Construct TheorySocializationTemporal LobeTheory of MindConceptsAutism spectrum disorderSocial information processingSuperior temporal sulcusSpectrum disorderPosterior superior temporal sulcusInformation processingSocial engagementSpecialized neural systemsModel of ASDFunctional neuroimaging researchSocial brainTemporal sulcusBrain mechanismsNeuroimaging researchSocial reciprocityRepetitive behaviorsNeural circuitryNeural systemsBrain endophenotypesDevelopmental studiesDevastating familySocial worldNeurodevelopmental disordersNeural structuresNeuroanatomical structures
2009
Action Understanding in the Superior Temporal Sulcus Region
Vander Wyk BC, Hudac CM, Carter EJ, Sobel DM, Pelphrey KA. Action Understanding in the Superior Temporal Sulcus Region. Psychological Science 2009, 20: 771-777. PMID: 19422619, PMCID: PMC2849148, DOI: 10.1111/j.1467-9280.2009.02359.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionBrain MappingChoice BehaviorColor PerceptionConcept FormationDominance, CerebralEmotionsFemaleHumansImage Processing, Computer-AssistedIntentionMagnetic Resonance ImagingMaleMotion PerceptionOxygenPattern Recognition, VisualPersonal Construct TheoryPsychomotor PerformanceSocial PerceptionTemporal LobeYoung AdultConceptsSuperior temporal sulcus regionEmotional expressionSTS regionPosterior superior temporal sulcus regionSulcus regionFunctional magnetic resonancePosterior STSAction understandingBiological motionEmotional contextNegative emotionsNegative regardPositive regardPerson's motionSocial actCongruentParticipantsIntentionEmotionsObjectsCongruencyPerceptionActionActressMagnetic resonance