2021
Association of Aβ deposition and regional synaptic density in early Alzheimer’s disease: a PET imaging study with [11C]UCB-J
O’Dell R, Mecca AP, Chen MK, Naganawa M, Toyonaga T, Lu Y, Godek TA, Harris JE, Bartlett HH, Banks ER, Kominek VL, Zhao W, Nabulsi NB, Ropchan J, Ye Y, Vander Wyk BC, Huang Y, Arnsten AFT, Carson RE, van Dyck CH. Association of Aβ deposition and regional synaptic density in early Alzheimer’s disease: a PET imaging study with [11C]UCB-J. Alzheimer's Research & Therapy 2021, 13: 11. PMID: 33402201, PMCID: PMC7786921, DOI: 10.1186/s13195-020-00742-y.Peer-Reviewed Original ResearchConceptsRegional Aβ depositionAβ depositionEarly Alzheimer's diseaseSynaptic lossSynaptic densityAlzheimer's diseaseDistribution volume ratioPositron emission tomographyHippocampal synaptic densityMild AD dementiaDeposition of AβSignificant inverse associationAmnestic mild cognitive impairmentWhole-brain analysisMild cognitive impairmentCerebellar reference regionPET imaging studiesPlaque burdenAD dementiaInverse associationPostmortem studiesClinical severityNeurodegenerative processesClinical diseaseLarge cohort
2010
Brain mechanisms for representing what another person sees
Heyda RD, Green SR, Vander Wyk B, Morris JP, Pelphrey KA. Brain mechanisms for representing what another person sees. NeuroImage 2010, 50: 693-700. PMID: 20056152, PMCID: PMC2824003, DOI: 10.1016/j.neuroimage.2009.12.101.Peer-Reviewed Original ResearchConceptsExtrastriate body areaParahippocampal place areaFunctional magnetic resonance imagingSocial cognitionVisual attentionDual-role hypothesisAttribution hypothesisPerson's visual attentionWhole-brain analysisSocial brainStimulus categoriesBrain mechanismsPlace areaVisible stimuliVisual regionsSame stimuliBrain regionsInterest analysisCognitionStimuliParticipants' viewsSpecific categoriesMagnetic resonance imagingExtrastriateHypothesis