Characterization of sequence variations within HPV16 isolates among Indian women: Prediction of causal role of rare non-synonymous variations within intact isolates in cervical cancer pathogenesis
Bhattacharjee B, Mandal N, Roy S, Sengupta S. Characterization of sequence variations within HPV16 isolates among Indian women: Prediction of causal role of rare non-synonymous variations within intact isolates in cervical cancer pathogenesis. Virology 2008, 377: 143-150. PMID: 18495198, DOI: 10.1016/j.virol.2008.04.007.Peer-Reviewed Original ResearchConceptsNon-synonymous changesCharacterization of sequence variationsPolymorphic variationDeleterious to protein functionHPV16 isolatesNon-synonymous variationsRare non-synonymous variationsDeleterious variationHaplotype backgroundNucleotide variationsSIFTS databaseDeleterious mutationsSequence variationSequence variantsProtein functionHPV16 genomeHaplotype analysisHaplotypesFunctional validationCervical cancer pathogenesisE-12IsolatesCaCx developmentCancer pathogenesisProductive infection