2025
Protein as a preoperative predictor – Impact of hypoalbuminemia on 30-day outcomes of breast reduction surgery
Knoedler S, Klimitz F, Diatta F, Perozzo F, Sofo G, Alfertshofer M, Cherubino M, Mayer H, Panayi A, Kim B, Pomahac B, Kauke-Navarro M. Protein as a preoperative predictor – Impact of hypoalbuminemia on 30-day outcomes of breast reduction surgery. Journal Of Plastic Reconstructive & Aesthetic Surgery 2025, 100: 144-152. DOI: 10.1016/j.bjps.2024.11.011.Peer-Reviewed Original ResearchBreast reduction surgeryImpact of hypoalbuminemiaReduction surgeryBody mass indexPostoperative complicationsSurgical outcomesMass indexAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseAssociated with adverse surgical outcomesPredictor of postoperative complicationsIncreased risk of complicationsQuality Improvement Program databasePreoperative nutritional assessmentSuperficial incisional infectionNormal albumin levelsBiomarkers of malnutritionHigher body mass indexAdverse surgical outcomesRisk of complicationsImprove surgical outcomesChronic obstructive pulmonary diseaseMultivariate logistic regressionObstructive pulmonary disease
2024
Unveiling Inequities: Racial Disparities in Risk-Reducing Mastectomy for Breast Cancer Prevention
Knoedler S, Diatta F, Klimitz F, Noel O, Kempa J, Obed D, Song S, Mayer H, Kim B, Kauke-Navarro M, Pomahac B, Butler P. Unveiling Inequities: Racial Disparities in Risk-Reducing Mastectomy for Breast Cancer Prevention. Clinical Breast Cancer 2024 DOI: 10.1016/j.clbc.2024.12.004.Peer-Reviewed Original ResearchRisk-reducing mastectomyMinority patientsRacial minority patientsBreast cancer preventionRacial disparitiesQuality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramWhite patientsCancer preventionStudy investigates racial disparitiesBreast cancer riskEquitable healthcare accessBlack patientsRates of obesityPrevalence of obesityBlack/African American womenImprovement programsPostoperative outcomesOutpatient surgeryAmerican College of Surgeons National Surgical Quality Improvement ProgramSurgeons National Surgical Quality Improvement ProgramHealth equityBreast cancer treatmentHealthcare accessCritical Assessment of Fellowship Director Gender and Ethnic Diversity across the Five Major Plastic Surgery Fellowships
Boroumand S, Stogniy S, Katsnelson B, Allam O, Vafa A, Sullivan J, Pomahac B, Haykal S, Butler P. Critical Assessment of Fellowship Director Gender and Ethnic Diversity across the Five Major Plastic Surgery Fellowships. Plastic & Reconstructive Surgery Global Open 2024, 12: e6286. PMID: 39600330, PMCID: PMC11596926, DOI: 10.1097/gox.0000000000006286.Peer-Reviewed Original ResearchFellowship directorsMentorship of traineesFellowship programsPatient populationReconstructive surgeryPlastic surgery fellowshipsProfessional society websitesSurgical workforcePercentage of malesMicrosurgerySociety websitesDirector demographicsFellowshipSurgeryPatientsFemale directorsRacial/ethnic minoritiesPerioperative safety of risk-reducing mastectomy
Knoedler S, Diatta F, Kasparbauer F, Knoedler L, Kim B, Pomahac B, Kauke-Navarro M. Perioperative safety of risk-reducing mastectomy. British Journal Of Cancer 2024, 131: 1721-1723. PMID: 39501091, PMCID: PMC11589771, DOI: 10.1038/s41416-024-02897-z.Peer-Reviewed Original ResearchLong-term Posttransplant-Related Bone Volumetric Changes in Eight Face Transplant Recipients – a Single Center Retrospective Case Series
Huelsboemer L, Boroumand S, Boroumand T, Vafa A, Parikh N, Chiarella L, Knoedler L, Stögner V, Hung P, Sadigh S, Haykal S, Pomahac B, Kauke-Navarro M. Long-term Posttransplant-Related Bone Volumetric Changes in Eight Face Transplant Recipients – a Single Center Retrospective Case Series. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024 DOI: 10.1016/j.bjps.2024.11.025.Peer-Reviewed Original ResearchFacial vascularized composite allograftBone volume changesBone volumeChronic rejection processRetrospective case seriesComputed tomography scanBone volume lossWilcoxon rank sum testNative boneSignificant median decreaseBone volume stabilityRank sum testFace transplant recipientsBone remodeling ratesVascularized composite allograftsChronic immunosuppressionTooth lossTransplant recipientsAllograft cohortCase seriesTomography scanVolume lossMedian decreaseMedical comorbiditiesHistopathological analysisTen Year Follow-up After Face Transplantation – a Single Center Retrospective Cohort Study
Huelsboemer L, Kauke-Navarro M, Boroumand S, Parikh N, Hosseini H, Yu C, Stögner V, Ko C, Perry B, Formica R, Hung P, Mahajan A, Azzi J, Murphy G, Pomahac B. Ten Year Follow-up After Face Transplantation – a Single Center Retrospective Cohort Study. American Journal Of Transplantation 2024 PMID: 39413877, DOI: 10.1016/j.ajt.2024.10.007.Peer-Reviewed Original ResearchChronic rejectionFace transplantationFollow-upSingle center retrospective cohort studyFunctional outcomesSensory returnAnalysis of functional outcomesMedian follow-upIncidence of malignancyMetabolic side effectsGraft rejection episodesComputed tomography angiogramRetrospective cohort studyEvidence of vasculopathyFollow-up periodLong-term outcomesYear follow-upFacial motor functionRejection episodesInfectious complicationsTransplant recipientsPatient ageGraft retentionMedical complicationsCohort studyAnalyzing Question Characteristics Influencing ChatGPT’s Performance in 3000 USMLE®-Style Questions
Alfertshofer M, Knoedler S, Hoch C, Cotofana S, Panayi A, Kauke-Navarro M, Tullius S, Orgill D, Austen W, Pomahac B, Knoedler L. Analyzing Question Characteristics Influencing ChatGPT’s Performance in 3000 USMLE®-Style Questions. Medical Science Educator 2024, 1-11. DOI: 10.1007/s40670-024-02176-9.Peer-Reviewed Original ResearchRisk Factors and Outcomes after Surgery for Malignant Neoplasm of the Parotid Gland: An ACS-NSQIP Study
Knoedler L, Knoedler S, Hoch C, Safi A, Wollenberg B, Alfertshofer M, Pomahac B, Kauke-Navarro M, Clune J. Risk Factors and Outcomes after Surgery for Malignant Neoplasm of the Parotid Gland: An ACS-NSQIP Study. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024 PMID: 39448324, DOI: 10.1016/j.bjps.2024.09.067.Peer-Reviewed Original ResearchBlood urea nitrogenRisk factorsRenal failureParotid glandMalignant neoplasmsAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseAssociated with higher creatinineNational Surgical Quality Improvement Program databaseMicrosurgical proceduresPre-operative risk factorsQuality Improvement Program databaseRisk of postoperative adverse eventsBlood urea nitrogen levelsHigher ASA classPostoperative adverse eventsOccurrence of complicationsPost-surgical outcomesTumor resectionComplication rateFlap surgeryPostoperative outcomesACS-NSQIPASA classHigher creatinineEvaluating two decades of traumatic amputations treated in US emergency departments: A multicenter epidemiological analysis from NEISS
Boroumand S, Ajjawi I, Park N, Huelsboemer L, Stögner V, Bach K, Kauke-Navarro M, Haykal S, Pomahac B, Colen D. Evaluating two decades of traumatic amputations treated in US emergency departments: A multicenter epidemiological analysis from NEISS. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 99: 63-66. PMID: 39353285, DOI: 10.1016/j.bjps.2024.09.068.Peer-Reviewed Original ResearchSLAM-Based Breast Reconstruction System for Surgical Guidance Using a Low-Cost Camera
Fu E, Zhou H, de la Lastra Á, Zhang R, Ayyala H, Broyles J, Pomahac B, Jagadeesan J. SLAM-Based Breast Reconstruction System for Surgical Guidance Using a Low-Cost Camera. IEEE Transactions On Medical Robotics And Bionics 2024, 6: 1345-1353. DOI: 10.1109/tmrb.2024.3464739.Peer-Reviewed Original ResearchReconstruction systemSoftware applicationsLow-cost RGB-D cameraRGB-D cameraLow-cost camerasBreast reconstruction surgerySimultaneous localizationAccurate reconstructionReconstruction modelCameraSLAM-basedSoftwareIRB-approved protocolSurface reconstructionPatient-specific 3DMastectomy siteAccuracy errorReconstructed breastAmount of tissueInframammary foldBreast moundSLAMReconstructive surgeryIntraoperative guidanceBreast shapeReading Between the Tabloids: An Objective Analysis of the Quality and Readability of Patient Encountered Online Material for Face Transplantation.
Boroumand S, Littleton A, Aregbe A, Gu E, Huelsboemer L, Stögner V, Lewis K, Kauke-Navarro M, Haykal S, Pomahac B. Reading Between the Tabloids: An Objective Analysis of the Quality and Readability of Patient Encountered Online Material for Face Transplantation. Journal Of Craniofacial Surgery 2024 PMID: 39471279, DOI: 10.1097/scs.0000000000010668.Peer-Reviewed Original ResearchNews sourcesOnline materialsNewsFace transplant programsThird-party sourcesReadability metricsFace transplantationReadabilityTransplant programsPost hoc Tukey multiple comparison testTukey's multiple comparison testMultiple comparison testReputable sourcesTabloidsReadability of online materialsAuthorshipOne-way ANOVATransplantationThird-party sitesJAMA benchmark criteriaDiscernmentEncountersJAMA benchmarksAn Update on the Survival of the First 50 Face Transplants Worldwide
Homsy P, Huelsboemer L, Barret J, Blondeel P, Borsuk D, Bula D, Gelb B, Infante-Cossio P, Lantieri L, Mardini S, Morelon E, Nasir S, Papay F, Petruzzo P, Rodriguez E, Özkan Ö, Özmen S, Pomahac B, Lassus P. An Update on the Survival of the First 50 Face Transplants Worldwide. JAMA Surgery 2024, 159 PMID: 39292472, PMCID: PMC11411447, DOI: 10.1001/jamasurg.2024.3748.Peer-Reviewed Original ResearchOverall survivalRejection episodesFace transplantationTransplanted graftsMedian follow-up timeAcute rejection episodesFollow-up timePredictors of survivalMulticenter cohort studyExtensive facial defectsEpisodes per yearLong-term survivalTransplant variablesFacial defectsNonpublished dataTransplant lossMedian numberFollow-upCohort studyReconstructive optionsPrimary outcomeSecondary outcomesTransplant survivalTransplantationTransplant centersRobotic-Assisted Microsurgery in Lymphatic Reconstruction.
Stögner V, Pucciarelli D, Pomahac B, Ayyala H. Robotic-Assisted Microsurgery in Lymphatic Reconstruction. Journal Of Craniofacial Surgery 2024 PMID: 39283135, DOI: 10.1097/scs.0000000000010608.Peer-Reviewed Original ResearchLymphatic reconstructionRobotic-assisted microsurgeryBreast cancer-related lymphedemaCancer-related lymphedemaSurgical outcomesYears of clinical experienceMicrosurgical reconstructionPatient groupLymphatic flowCancer incidenceSurvival rateLymphatic anastomosisMicrosurgical performanceClinical experienceMicrosurgeryLower extremitiesHuman vesselsLymphatic microsurgeryPatientsMicrosurgical robotPhysiological tremorThe impact of age on outcomes after breast reduction surgery – A multi-institutional data analysis of 40,958 cases
Knoedler S, Perozzo F, Jiang J, Kosyk M, Alfertshofer M, Schenck T, Kern B, Sofo G, Knoedler L, Panayi A, Pomahac B, Kauke-Navarro M, Kim B. The impact of age on outcomes after breast reduction surgery – A multi-institutional data analysis of 40,958 cases. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 98: 318-330. PMID: 39321535, DOI: 10.1016/j.bjps.2024.09.027.Peer-Reviewed Original ResearchReduction mammoplastyFemale patientsMedical complicationsImpact of ageAmerican College of Surgeons National Surgical Quality Improvement ProgramSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramPatients aged <Patients aged >Breast reduction surgeryAdult female patientsQuality Improvement ProgramPostoperative morbiditySurgical complicationsPostoperative outcomesPatient ageReduction surgeryDeterminants of riskMultivariate analysisAmerican CollegeComplicationsLow riskPatientsMammoplastyThe role of C4d and donor specific antibodies in face and hand transplantation—a systematic review
Huelsboemer L, Moscarelli J, Dony A, Boroumand S, Kochen A, Knoedler L, Yu C, Hauc S, Stögner V, Formica R, Lian C, Murphy G, Pomahac B, Kauke-Navarro M. The role of C4d and donor specific antibodies in face and hand transplantation—a systematic review. Frontiers In Transplantation 2024, 3: 1442006. PMID: 39291278, PMCID: PMC11405992, DOI: 10.3389/frtra.2024.1442006.Peer-Reviewed Original ResearchDonor-specific antibodiesSerum donor-specific antibodiesAntibody-mediated rejectionHigher rejection gradesVascularized composite allotransplantationC4d depositionRejection gradeCellular rejectionRejection episodesSpecific antibodiesDonor-specific antibody statusManagement of antibody-mediated rejectionFace transplantationAcute cellular rejectionAcute rejection episodesAssociated with high gradeTime of biopsyAntibody mediated rejectionFisher's exact testMann-Whitney U testSystematic review of electronic databasesMechanisms of rejectionSystematic reviewReview of electronic databasesC4d stainingEvolution of Vascularized Composite Allotransplantation
Huelsboemer L, Pomahac B. Evolution of Vascularized Composite Allotransplantation. 2024, 15-27. DOI: 10.1007/978-3-031-57132-9_3.Peer-Reviewed Original ResearchVascularized composite allotransplantationSolid organ transplantationProlongation of ischemia timeReconstruction of complex tissue defectsContext of vascularized composite allotransplantationDevelopment of non-toxicTolerogenic strategiesChronic rejectionImmunosuppressive medicationsTolerance inductionComplex tissue defectsPatient selectionIschemia timeTo Face Transplant or Not Face Transplant? Evaluating the Limitations of ChatGPT's Consideration of Ethical Themes
Boroumand S, Gu E, Huelsboemer L, Stögner V, Parikh N, Kauke-Navarro M, Pomahac B. To Face Transplant or Not Face Transplant? Evaluating the Limitations of ChatGPT's Consideration of Ethical Themes. Annals Of Plastic Surgery 2024, 93: 527-529. PMID: 39331750, DOI: 10.1097/sap.0000000000004072.Peer-Reviewed Original ResearchLetter in Reply to Comment on: Gynecomastia Surgery in 4996 Male Patients Over 14 Years: A Retrospective Analysis of Surgical Trends, Predictive Risk Factors, and Short-Term Outcomes
Kauke-Navarro M, Klimitz F, Pomahac B. Letter in Reply to Comment on: Gynecomastia Surgery in 4996 Male Patients Over 14 Years: A Retrospective Analysis of Surgical Trends, Predictive Risk Factors, and Short-Term Outcomes. Aesthetic Plastic Surgery 2024, 1-3. PMID: 39085527, DOI: 10.1007/s00266-024-04285-7.Peer-Reviewed Original ResearchC-reactive protein orchestrates acute allograft rejection in vascularized composite allotransplantation via subset-selective monocyte activation
Kiefer J, Zeller J, Schneider L, Thomé J, McFadyen J, Hoerbrand I, Lang F, Deiss E, Bogner B, Schaefer A, Chevalier N, Horner V, Kreuzaler S, Kneser U, Kauke-Navarro M, Braig D, Woollard K, Pomahac B, Peter K, Eisenhardt S. C-reactive protein orchestrates acute allograft rejection in vascularized composite allotransplantation via subset-selective monocyte activation. Journal Of Advanced Research 2024 PMID: 38992424, DOI: 10.1016/j.jare.2024.07.007.Peer-Reviewed Original ResearchAcute allograft rejectionC-reactive proteinVascularized composite allotransplantationAllograft rejectionAcute rejectionAllograft survivalGraft rejectionAttenuate acute allograft rejectionPreventing acute allograft rejectionImmune responseLong-term allograft survivalFacial vascularized composite allotransplantationClinical allograft rejectionReduced allograft survivalChronic allograft rejectionIntravital imagingNon-classical monocytesMarkers of inflammationAcute-phase reactantsImmune-inflammatory reactionPro-inflammatory propertiesMononuclear phagocyte systemAcute-phase responseGraft infiltrationInnate immune responseSurgical Management of Breast Capsular Contracture—A Multi-institutional Data Analysis of Risk Factors for Early Complications
Knoedler S, Knoedler L, Boroumand S, Alfertshofer M, Diatta F, Sofo G, Huelsboemer L, Hansen F, Könneker S, Kim B, Perozzo F, Ayyala H, Allam O, Pomahac B, Kauke-Navarro M. Surgical Management of Breast Capsular Contracture—A Multi-institutional Data Analysis of Risk Factors for Early Complications. Aesthetic Plastic Surgery 2024, 1-12. PMID: 38926252, DOI: 10.1007/s00266-024-04203-x.Peer-Reviewed Original ResearchRisk factorsPostoperative complicationsCC surgeryInpatient settingMedical complicationsAmerican College of Surgeons National Surgical Quality Improvement Program databaseRisk factors of postoperative complicationsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseImplant-based breast surgeryMultivariate analysisPreoperative diagnosis of hypertensionFactors of postoperative complicationsQuality Improvement Program databaseLevel of Evidence IIIThis journalEvidence-Based Medicine ratingsAnalysis of risk factorsDay complication ratesDays follow-upEvidence IIIThis journalLevel of evidenceSurgical adverse eventsDiagnosis of hypertensionMulti-institutional dataTreatment of CC