2020
The Role of Lower Extremity Amputation in Chronic Limb-Threatening Ischemia
Kim TI, Mena C, Sumpio BE. The Role of Lower Extremity Amputation in Chronic Limb-Threatening Ischemia. International Journal Of Angiology 2020, 29: 149-155. PMID: 32904807, PMCID: PMC7458760, DOI: 10.1055/s-0040-1710075.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaImproved limb salvage ratesChronic limb threatening ischemiaRole of amputationLimb salvage rateLimb threatening ischemiaLimb-threatening ischemiaPeripheral artery diseaseLower Extremity AmputationMajor amputationPrimary amputationArtery diseaseLimb salvageSalvage rateExtremity amputationImproved careLimb lossSevere formMultidisciplinary teamAmputationRevascularizationIschemiaPatientsHigh rateSalvage
2019
Infected Ischemic Foot: Investigation
Miller S, Sumpio B, Sumpio B. Infected Ischemic Foot: Investigation. 2019, 481-495. DOI: 10.1007/978-3-319-17918-6_38.Peer-Reviewed Original ResearchIschemic footAssessment of ischemiaFocused physical examDiabetic patientsLimb salvageWound infectionPhysical examAncillary testingPatient historyPathologic processesDisease resultsSeparate diagnosisDiagnostic imagingDistinct diagnosisInfectionPrimary locationHealing capacityDistal partDiagnosisFootLaboratory testingCommon occurrenceUlcerationIschemiaPatients
2017
RADIOTRACER IMAGING ALLOWS FOR ASSESSMENT OF SERIAL CHANGES IN ANGIOSOME FOOT PERFUSION FOLLOWING REVASCULARIZATION AND PREDICTS LIMB SALVAGE OUTCOMES IN PATIENTS WITH CRITICAL LIMB ISCHEMIA
Buckley J, Mena-Hurtado C, Jeon S, Papademetris X, Blume P, Sumpio B, Sinusas A, Stacy M. RADIOTRACER IMAGING ALLOWS FOR ASSESSMENT OF SERIAL CHANGES IN ANGIOSOME FOOT PERFUSION FOLLOWING REVASCULARIZATION AND PREDICTS LIMB SALVAGE OUTCOMES IN PATIENTS WITH CRITICAL LIMB ISCHEMIA. Journal Of The American College Of Cardiology 2017, 69: 1393. DOI: 10.1016/s0735-1097(17)34782-4.Peer-Reviewed Original Research
2016
Explantation of infected aortic aneurysm and endograft with ascending aorta to mesenteric bypass for mesenteric ischemia
Gates L, Chin JA, Bonde PN, Chaar C, Sumpio BE, Sarac TP. Explantation of infected aortic aneurysm and endograft with ascending aorta to mesenteric bypass for mesenteric ischemia. Journal Of Vascular Surgery 2016, 65: 219-223. PMID: 27183855, DOI: 10.1016/j.jvs.2016.03.411.Peer-Reviewed Original ResearchMeSH KeywordsAgedAneurysm, InfectedAnti-Bacterial AgentsAortic Aneurysm, AbdominalAortographyBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationCeliac ArteryCoated Materials, BiocompatibleCollateral CirculationComputed Tomography AngiographyDevice RemovalEndovascular ProceduresHepatic ArteryHumansMaleMesenteric Artery, SuperiorMesenteric IschemiaMesenteric Vascular OcclusionProsthesis-Related InfectionsReoperationRifampinSplanchnic CirculationTreatment OutcomeConceptsAortic aneurysmBilateral renal arteriesSurgical revascularization techniquesSuperior mesenteric arteryAbdominal aortic aneurysmAxillobifemoral bypassGelsoft graftAbdominal painMesenteric ischemiaRevascularization techniquesThoracoabdominal aortaInferior mesentericMesenteric arteryRenal arterySurgical issuesMesenteric bypassAneurysmsAortaPrevious treatmentEndograftArteryBypassMesentericResectionIschemia
2015
Venous Ulcer: Late Complication of a Traumatic Arteriovenous Fistula
Young CJ, Dardik A, Sumpio B, Indes J, Muhs B, Chaar C. Venous Ulcer: Late Complication of a Traumatic Arteriovenous Fistula. Annals Of Vascular Surgery 2015, 29: 836.e1-836.e3. PMID: 25725283, DOI: 10.1016/j.avsg.2014.11.020.Peer-Reviewed Case Reports and Technical NotesConceptsTraumatic AVFsLate complicationsArteriovenous fistula formationCongestive heart failureTraumatic arteriovenous fistulaDistal ischemiaHard signsVenous dilatationHeart failureInitial presentationOpen repairFistula formationVenous congestionArteriovenous fistulaVascular injuryCase reportAVFOperating roomComplicationsInjurySignsFistulaIschemiaUlcersPatients
2014
Contemporary assessment of foot perfusion in patients with critical limb ischemia
Benitez E, Sumpio BJ, Chin J, Sumpio BE. Contemporary assessment of foot perfusion in patients with critical limb ischemia. Seminars In Vascular Surgery 2014, 27: 3-15. PMID: 25812754, DOI: 10.1053/j.semvascsurg.2014.12.001.Peer-Reviewed Original ResearchConceptsCritical limb ischemiaLimb ischemiaFoot perfusionLower extremity perfusionPeripheral arterial diseaseTranscutaneous oxygen monitoringRevascularization techniquesArterial diseaseFoot ulcerationLimb salvageRevascularization therapyFluorescent angiographyPatient outcomesEndovascular proceduresDisease processPatient careIschemiaDiagnostic imagingPatientsPerfusionImaging modalitiesLaser DopplerOxygen monitoringPlanning interventionsModalities
2010
The role of interdisciplinary team approach in the management of the diabetic foot A Joint Statement from the Society for Vascular Surgery and the American Podiatric Medical Association
Sumpio BE, Armstrong DG, Lavery LA, Andros G, group S. The role of interdisciplinary team approach in the management of the diabetic foot A Joint Statement from the Society for Vascular Surgery and the American Podiatric Medical Association. Journal Of Vascular Surgery 2010, 51: 1504-1506. PMID: 20488327, DOI: 10.1016/j.jvs.2010.04.010.Peer-Reviewed Original ResearchConceptsAmerican Podiatric Medical AssociationDiabetic footVascular surgeryTeam approachCritical limb ischemiaMultidisciplinary team approachCare of patientsInterdisciplinary team approachMedical AssociationDiabetic populationLimb ischemiaMultidisciplinary teamClinical issuesJoint statementPatientsSurgeryCareBeneficial impactAssociationFootRepresentative groupIschemiaThe Role of Interdisciplinary Team Approach in the Management of the Diabetic Foot
Sumpio BE, Armstrong DG, Lavery LA, Andros G. The Role of Interdisciplinary Team Approach in the Management of the Diabetic Foot. Journal Of The American Podiatric Medical Association 2010, 100: 309-11. PMID: 20660885, DOI: 10.7547/1000309.Peer-Reviewed Original ResearchConceptsAmerican Podiatric Medical AssociationDiabetic footTeam approachCritical limb ischemiaMultidisciplinary team approachCare of patientsInterdisciplinary team approachDiabetic populationLimb ischemiaVascular surgeryMultidisciplinary teamClinical issuesPatientsMedical AssociationCareBeneficial impactJoint statementFootRepresentative groupIschemiaSurgery
2000
Acute Mesenteric Ischemia
Sai Sudhakar C, Pollock J, Sumpio B. Acute Mesenteric Ischemia. 2000, 559-571. DOI: 10.1007/978-1-4612-1190-7_46.Peer-Reviewed Original ResearchAcute mesenteric ischemiaMesenteric ischemiaMortality rateAcute abdominal painHigh mortality rateDefinitive diagnostic methodAbdominal painSignificant morbidityAbdominal diseasePatient referralIntestinal disordersDiffuse symptomsEarly diagnosisIschemiaDiagnostic methodsMorbidityPainPatientsHospitalReferralSymptomsDiseaseDiagnosis
1997
Mesenteric ischemia secondary to cocaine abuse: case reports and literature review.
Sudhakar CB, Al-Hakeem M, MacArthur JD, Sumpio BE. Mesenteric ischemia secondary to cocaine abuse: case reports and literature review. The American Journal Of Gastroenterology 1997, 92: 1053-4. PMID: 9177533.Peer-Reviewed Original Research
1993
Common pathway of endothelial-leukocyte interaction in shock, ischemia, and reperfusion
McMillen M, Huribal M, Sumpio B. Common pathway of endothelial-leukocyte interaction in shock, ischemia, and reperfusion. The American Journal Of Surgery 1993, 166: 557-562. PMID: 8238752, DOI: 10.1016/s0002-9610(05)81153-5.Peer-Reviewed Original ResearchConceptsBlood flowVascular endotheliumSignificant organ dysfunctionImpaired blood flowEndothelial-leukocyte interactionsRestoration of functionOrgan dysfunctionReperfusion injuryInflammatory cellsIschemia resultsInflammatory responseLeukocyte adherenceFurther injuryNeutrophil interactionsOxygen deliveryCurrent evidenceCellular injuryIschemiaEndothelial cellsInjuryCommon pathwayEndotheliumCurrent literatureCellular functionsAnaerobic mechanismsEndothelin-Stimulated Human Monocytes Produce Prostaglandin E2 but Not Leukotriene B4
McMillen M, Huribal M, Kumar R, Sumpio B. Endothelin-Stimulated Human Monocytes Produce Prostaglandin E2 but Not Leukotriene B4. Journal Of Surgical Research 1993, 54: 331-335. PMID: 8392650, DOI: 10.1006/jsre.1993.1053.Peer-Reviewed Original ResearchConceptsProstaglandin E2Pg/Human monocytesPost-traumatic immunosuppressionMonocytes/macrophagesBacterial lipopolysaccharide (LPS) stimulationEndothelin increaseM endothelinInterleukin-6Immune functionLeukotriene B4PGE2 productionVascular endotheliumEndothelinLipopolysaccharide (LPS) stimulationInjuryMonocytesAcid peptideE2B4HrActivationImmunosuppressionIschemiaMajor role
1991
Amelioration of renal ischemic injury by phosphocreatine
Rodriguez R, Stepke M, Maitz S, Cuono C, Sumpio B. Amelioration of renal ischemic injury by phosphocreatine. Journal Of Surgical Research 1991, 51: 271-274. PMID: 1921364, DOI: 10.1016/0022-4804(91)90106-v.Peer-Reviewed Original ResearchConceptsRenal ischemic injuryInitial ischemic insultPerfusion of kidneysKrebs-bicarbonate solutionMin of normothermicMM phosphocreatineRenal functionIschemic injuryKidney functionIschemic insultRenal arteryVivo ischemiaWarm ischemiaKrebs solutionKidneyPhosphocreatineAddition of phosphocreatineIschemiaSignificant improvementRegeneration of ATPGFRArteryNormothermicUreterInjury
1987
Comparison of effects of ATP-MgCl2 and adenosine-MgCl2 on renal function following ischemia
Sumpio BE, Hull MJ, Baue AE, Chaudry IH. Comparison of effects of ATP-MgCl2 and adenosine-MgCl2 on renal function following ischemia. American Journal Of Physiology 1987, 252: r388-r393. PMID: 3492930, DOI: 10.1152/ajpregu.1987.252.2.r388.Peer-Reviewed Original ResearchConceptsRenal functionATP-MgCl2Warm ischemiaATP-MgCl2 treatmentKrebs-HCO3 bufferMM ATP-MgCl2Comparison of effectsNormothermic ischemiaTransient improvementIschemiaSalutary effectsControl valuesUrine samplesFunctional parametersKidneyMajor breakdown productAdenosineTreatmentBreakdown productsMmHgPerfusateMinAdministration
1985
Accelerated functional recovery of isolated rat kidney with ATP-MgCl2 after warm ischemia
Sumpio B, Chaudry I, Clemens M, Baue A. Accelerated functional recovery of isolated rat kidney with ATP-MgCl2 after warm ischemia. AJP Regulatory Integrative And Comparative Physiology 1985, 248: r752-r752. DOI: 10.1152/ajpregu.1985.248.6.r752-r.Peer-Reviewed Original ResearchAdenosine Triphosphate—Magnesium Chloride Ameliorates Reperfusion Injury Following Ischemia as Determined by Phosphorus Nuclear Magnetic Resonance
Sumpio B, Chaudry I, Baue A. Adenosine Triphosphate—Magnesium Chloride Ameliorates Reperfusion Injury Following Ischemia as Determined by Phosphorus Nuclear Magnetic Resonance. JAMA Surgery 1985, 120: 233-240. PMID: 3872113, DOI: 10.1001/archsurg.1985.01390260091013.Peer-Reviewed Original ResearchConceptsIntracellular acidosisPerfusate flowATP levelsAdenosine triphosphate-magnesium chlorideRenal ATP levelsMinutes of reperfusionTissue ATP levelsEffects of ischemiaAdenosine triphosphateML/minPostischemic administrationReperfusion injuryRenal ischemiaWarm ischemiaATP-MgCl2ReperfusionIschemiaInorganic phosphate peakIntracellular adenosine triphosphatePi peakRat kidneyAcidosisATP depletionMinutesMagnetic resonance
1984
Accelerated functional recovery of isolated rat kidney with ATP-MgCl2 after warm ischemia
Sumpio BE, Chaudry IH, Clemens MG, Baue AE. Accelerated functional recovery of isolated rat kidney with ATP-MgCl2 after warm ischemia. American Journal Of Physiology 1984, 247: r1047-r1053. PMID: 6334446, DOI: 10.1152/ajpregu.1984.247.6.r1047.Peer-Reviewed Original ResearchConceptsRenal perfusate flow rateMM ATP-MgCl2Min of perfusionIsolated rat kidneyATP-MgCl2Renal functionWarm ischemiaWhole kidney inulin clearanceRat kidneyAccelerated functional recoveryMin of reperfusionMin of ischemiaUrine flow rateTissue ATP levelsFractional absorptionFunctional recoveryNormothermic ischemiaIschemia resultsMin ischemiaPerfusate flow rateInulin clearanceEarly recoverySystemic effectsIschemiaSodium values