2003
Fibronectin blocks p38 and jnk activation by cyclic strain in Caco-2 cells
Zhang J, Li W, Sumpio BE, Basson MD. Fibronectin blocks p38 and jnk activation by cyclic strain in Caco-2 cells. Biochemical And Biophysical Research Communications 2003, 306: 746-749. PMID: 12810082, DOI: 10.1016/s0006-291x(03)01044-1.Peer-Reviewed Original ResearchConceptsIntestinal epithelial responsesIntestinal epithelial proliferationCaco-2 intestinal epithelial cellsIntestinal epithelial cellsHuman Caco-2 intestinal epithelial cellsCaco-2 cellsPlasma fibronectinInfectious conditionsEpithelial responseFibronectin levelsEpithelial proliferationIntestinal epitheliumEpithelial cellsRepetitive forcesBasement membraneCollagen ICollagen IVIntracellular signalingP38JNK activationActivationCellsStrain activationTissueFibronectin
1997
Endothelial Cell Effect on Smooth Muscle Cell Collagen Synthesis
Powell R, Hydowski J, Frank O, Bhargava J, Sumpio B. Endothelial Cell Effect on Smooth Muscle Cell Collagen Synthesis. Journal Of Surgical Research 1997, 69: 113-118. PMID: 9202656, DOI: 10.1006/jsre.1997.5045.Peer-Reviewed Original ResearchConceptsGene expressionSMC gene expressionExtracellular matrixEndothelial cellsOpposite endothelial cellsEC-SMC interactionsCell lysate fractionTrichloroacetic acid-precipitable countsCollagen synthesis regulationSynthesis regulationSMC DNANorthern analysisBovine aortic SMCEndothelial cell effectsLysate fractionAcid-precipitable countsType IAortic SMCsCollagen synthesisMatrigelSubstrate compositionCulture substrateType I collagenFibronectinExpression