2006
Nicotine enhances human vascular endothelial cell expression of ICAM-1 and VCAM-1 via protein kinase C, p38 mitogen-activated protein kinase, NF-κB, and AP-1
Ueno H, Pradhan S, Schlessel D, Hirasawa H, Sumpio BE. Nicotine enhances human vascular endothelial cell expression of ICAM-1 and VCAM-1 via protein kinase C, p38 mitogen-activated protein kinase, NF-κB, and AP-1. Cardiovascular Toxicology 2006, 6: 39-50. PMID: 16845181, DOI: 10.1385/ct:6:1:39.Peer-Reviewed Original ResearchConceptsHuman umbilical vein endothelial cellsICAM-1VCAM-1NF-κBAdhesion moleculesP38 mitogen-activated protein kinaseProtein kinase CMitogen-activated protein kinaseVascular cell adhesion moleculeEndothelial cellsExposure of HUVECsCellular adhesion molecule expressionAP-1Vascular endothelial cell expressionMajor risk factorEffects of nicotineEtiology of atherosclerosisP38 MAPKAdhesion molecule expressionIntercellular adhesion moleculeTranscription factor NF-κBCellular adhesion moleculesEndothelial cell expressionFactor NF-κBUmbilical vein endothelial cells
2003
NICOTINE ENHANCES ENDOTHELIAL CELL (EC) ADHESION MOLECULE EXPRESSION VIA P38 MITOGEN-ACTIVATED PROTEIN KINASE (MAPK)
Ueno H, Pradhan S, Schlessel D, Hirasawa H, Sumpio B. NICOTINE ENHANCES ENDOTHELIAL CELL (EC) ADHESION MOLECULE EXPRESSION VIA P38 MITOGEN-ACTIVATED PROTEIN KINASE (MAPK). Shock 2003, 19: 30. DOI: 10.1097/00024382-200306001-00088.Peer-Reviewed Original ResearchProtein kinaseP38 mitogenCell adhesion molecule expressionKinaseAdhesion molecule expressionMitogenExpressionMolecule expression