Greater baseline connectivity of the salience and negative affect circuits are associated with natural improvements in anxiety over time in untreated participants
Holt-Gosselin B, Keller AS, Chesnut M, Ling R, Grisanzio KA, Williams LM. Greater baseline connectivity of the salience and negative affect circuits are associated with natural improvements in anxiety over time in untreated participants. Journal Of Affective Disorders 2021, 295: 366-376. PMID: 34492429, DOI: 10.1016/j.jad.2021.08.039.Peer-Reviewed Original ResearchConceptsAnxiety symptom improvementNegative affect circuitSymptoms of anxietyCognitive controlSymptom improvementSad facesLifestyle activitiesPositive affectBehavioral therapyCircuit connectivityBaseline connectivityDefault modeRight insulaPsychosocial functionSocial interactionAnxiety improvementActivity engagementDepression symptomsAnxietySalienceNeural circuit functionNatural improvementUntreated participantsCausal inferenceLimited researchDefault Mode Network Moderates the Relationship Between Lifestyle Changes and Natural Improvements in Clinical Symptoms Over Time in Untreated Participants
Holt-Gosselin B, Keller A, Chesnut M, Williams L. Default Mode Network Moderates the Relationship Between Lifestyle Changes and Natural Improvements in Clinical Symptoms Over Time in Untreated Participants. Biological Psychiatry 2021, 89: s111. DOI: 10.1016/j.biopsych.2021.02.287.Peer-Reviewed Original Research