Coping Strategies, Neural Structure, and Depression and Anxiety During the COVID-19 Pandemic: A Longitudinal Study in a Naturalistic Sample Spanning Clinical Diagnoses and Subclinical Symptoms
Holt-Gosselin B, Tozzi L, Ramirez CA, Gotlib IH, Williams LM. Coping Strategies, Neural Structure, and Depression and Anxiety During the COVID-19 Pandemic: A Longitudinal Study in a Naturalistic Sample Spanning Clinical Diagnoses and Subclinical Symptoms. Biological Psychiatry Global Open Science 2021, 1: 261-271. PMID: 34604834, PMCID: PMC8479487, DOI: 10.1016/j.bpsgos.2021.06.007.Peer-Reviewed Original ResearchAnxious arousal symptomsMaladaptive coping strategiesArousal symptomsCoping strategiesSubclinical symptomsBrain regionsNeural structuresGray matter volumePreregistered hypothesesNeural factorsAnhedonia symptomsStressful eventsDepression symptomsGeneral linear mixed-effects modelsNaturalistic sampleLongitudinal studyMatter volumeAmygdala volumeAnxietyLower structural integrityCOVID-19 pandemicT1-weighted scansCortical thicknessPsychiatric diagnosisClinical symptoms