2023
An adversarial collaboration protocol for testing contrasting predictions of global neuronal workspace and integrated information theory
Melloni L, Mudrik L, Pitts M, Bendtz K, Ferrante O, Gorska U, Hirschhorn R, Khalaf A, Kozma C, Lepauvre A, Liu L, Mazumder D, Richter D, Zhou H, Blumenfeld H, Boly M, Chalmers D, Devore S, Fallon F, de Lange F, Jensen O, Kreiman G, Luo H, Panagiotaropoulos T, Dehaene S, Koch C, Tononi G. An adversarial collaboration protocol for testing contrasting predictions of global neuronal workspace and integrated information theory. PLOS ONE 2023, 18: e0268577. PMID: 36763595, PMCID: PMC9916582, DOI: 10.1371/journal.pone.0268577.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingGlobal neuronal workspaceConscious visual perceptionIntracranial electroencephalographyVisual consciousnessVisual perceptionConscious experienceBrain activityIntegrated Information TheoryMajor theoriesAdversarial collaborationHuman brainDifferent accountsOpen science practicesStudy protocolMagnetic resonance imagingConsciousnessInformation theoryTheory proponentsTheoryPerceptionResonance imagingElectroencephalographyCorrelatesRelationship
2022
Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity
Kronemer S, Aksen M, Ding J, Ryu J, Xin Q, Ding Z, Prince J, Kwon H, Khalaf A, Forman S, Jin D, Wang K, Chen K, Hu C, Agarwal A, Saberski E, Wafa S, Morgan O, Wu J, Christison-Lagay K, Hasulak N, Morrell M, Urban A, Todd Constable R, Pitts M, Mark Richardson R, Crowley M, Blumenfeld H. Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity. Nature Communications 2022, 13: 7342. PMID: 36446792, PMCID: PMC9707162, DOI: 10.1038/s41467-022-35117-4.Peer-Reviewed Original ResearchConceptsSubcortical networksConscious visual perceptionVisual perception taskNeurophysiology of consciousnessExecutive control networkMajor brain networksDefault mode networkFrontal eye fieldOvert reportPerception taskVisual consciousnessConscious perceptionFusiform cortexVisual perceptionAnterior insulaConscious experienceSalience networkBrain networksMode networkAnterior cingulateEye fieldTask reportControl networkFMRI changesNeural circuitsA machine‐learning approach for predicting impaired consciousness in absence epilepsy
Springer M, Khalaf A, Vincent P, Ryu JH, Abukhadra Y, Beniczky S, Glauser T, Krestel H, Blumenfeld H. A machine‐learning approach for predicting impaired consciousness in absence epilepsy. Annals Of Clinical And Translational Neurology 2022, 9: 1538-1550. PMID: 36114696, PMCID: PMC9539371, DOI: 10.1002/acn3.51647.Peer-Reviewed Original ResearchEarly neural activity changes associated with stimulus detection during visual conscious perception
Khalaf A, Kronemer SI, Christison-Lagay K, Kwon H, Li J, Wu K, Blumenfeld H. Early neural activity changes associated with stimulus detection during visual conscious perception. Cerebral Cortex 2022, 33: 1347-1360. PMID: 35446937, DOI: 10.1093/cercor/bhac140.Peer-Reviewed Original ResearchConceptsVisual conscious perceptionNeural activity changesConscious perceptionStimulus detectionContinuous performance taskCortical neural signalsGamma power increaseGamma power changesMedial occipital cortexMedial temporal cortexParietal-temporal cortexTarget letterNontarget stimuliPerformance taskVisual stimuliStimulus onsetPopulation neural activityBroadband gamma powerNeural activityTemporal cortexGamma powerActivity changesMotor responsePremotor areasOccipital cortex
2021
Early cortical signals in visual stimulus detection
Kwon H, Kronemer SI, Christison-Lagay KL, Khalaf A, Li J, Ding JZ, Freedman NC, Blumenfeld H. Early cortical signals in visual stimulus detection. NeuroImage 2021, 244: 118608. PMID: 34560270, DOI: 10.1016/j.neuroimage.2021.118608.Peer-Reviewed Original ResearchConceptsConscious perceptionStimulus onsetLeft hemisphere language areasVisual conscious perceptionWord recall taskBilateral medial temporal corticesVerbal memory taskConscious visual perceptionLeft rostral middle frontal gyrusHemisphere language areasVisual stimulus detectionMiddle frontal gyrusGamma power increaseGamma power changesDefault mode networkMedial temporal regionsBroadband gamma activityNeural activity changesMedial temporal cortexRight frontal cortexSignal detection networkMultiple cortical regionsRostral middle frontal gyrusMemory taskRecall task