2018
Update in Spontaneous Coronary Artery Dissection
Ingrassia J, Diver D, Vashist A. Update in Spontaneous Coronary Artery Dissection. Journal Of Clinical Medicine 2018, 7: 228. PMID: 30134627, PMCID: PMC6162848, DOI: 10.3390/jcm7090228.Peer-Reviewed Original ResearchAntiplatelet Therapy in Coronary Artery Disease: A Daunting Dilemma
Chaturvedula S, Diver D, Vashist A. Antiplatelet Therapy in Coronary Artery Disease: A Daunting Dilemma. Journal Of Clinical Medicine 2018, 7: 74. PMID: 29642547, PMCID: PMC5920448, DOI: 10.3390/jcm7040074.Peer-Reviewed Original ResearchAcute coronary syndromePercutaneous coronary interventionDAPT durationDuration of DAPTOlder patient populationCoronary artery diseasePotent antiplatelet agentsMajor societal guidelinesNovel anticoagulant drugsAntiplatelet therapyCoronary syndromeMultiple comorbiditiesP2Y12 inhibitorsTriple therapyCoronary interventionAntiplatelet agentsArtery diseasePatient populationSocietal guidelinesAnticoagulant drugsOptimal durationClinical decisionAvailable evidenceTherapyNew stent
2008
Noninvasive Detection of Risk for Emotion Provoked Myocardial Ischemia
Burg MM, Graeber B, Vashist A, Collins D, Earley C, Liu J, Lampert R, Soufer R. Noninvasive Detection of Risk for Emotion Provoked Myocardial Ischemia. Psychosomatic Medicine 2008, 71: 14-20. PMID: 18941131, PMCID: PMC2739989, DOI: 10.1097/psy.0b013e318187c035.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngerAngiotensin-Converting Enzyme InhibitorsBlood PressureCoronary DiseaseEpinephrineFemaleHeart RateHumansImagery, PsychotherapyMaleManometryMiddle AgedMyocardial IschemiaNorepinephrinePlethysmographyPredictive Value of TestsPulsatile FlowRiskSensitivity and SpecificityStress, PsychologicalTomography, Emission-Computed, Single-PhotonVascular ResistanceConceptsPeripheral arterial tonometryCoronary artery diseasePAT ratioMyocardial ischemiaMajor adverse cardiac eventsStable coronary artery diseaseLower PAT ratioMental stress ischemiaAdverse cardiac eventsNew perfusion defectsCT myocardial perfusionSensitivity/specificityStress ischemiaArterial tonometryCardiac eventsArtery diseaseBlood pressureACE inhibitionPerfusion defectsHeart rateMyocardial perfusionPatientsEnzyme inhibitorsClinical settingIschemia
2007
Does cardiac SPECT using attenuation and scatter correction accurately predict coronary artery disease in a minority women population?
Vashist A, Collins D, Prasad Y, Blum S, Heller E. Does cardiac SPECT using attenuation and scatter correction accurately predict coronary artery disease in a minority women population? Medical Science Monitor 2007, 13: cr386-390. PMID: 17767117.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingCoronary artery diseasePositive predictive valueWomen patientsArtery diseaseSensitivity of MPIPredictive valueExercise stress testingGroup of patientsStress testingRecent revascularizationCardiac catheterizationCoronary angiographyFavorable prognosisRisk stratificationCatheterization laboratoryGeneral populationPatientsWomen populationPerfusion imagingAttenuation/scatter correctionNuclear imagingAngiographyPrognosisDiagnostic methods
2006
C-Reactive Protein and Vulnerability to Mental Stress-Induced Myocardial Ischemia
Shah R, Burg MM, Vashist A, Collins D, Liu J, Jadbabaie F, Graeber B, Earley C, Lampert R, Soufer R. C-Reactive Protein and Vulnerability to Mental Stress-Induced Myocardial Ischemia. Molecular Medicine 2006, 12: 269-274. PMID: 17380191, PMCID: PMC1829194, DOI: 10.2119/2006-00077.shah.Peer-Reviewed Original ResearchConceptsC-reactive proteinCoronary artery diseaseMyocardial perfusion imagingTransthoracic echocardiographyCRP levelsMental stressRisk markersMyocardial ischemiaLevels of CRPNew regional wall motion abnormalitiesAssociation of CRPRelationship of CRPSimultaneous single-photon emissionStable coronary artery diseaseUnivariate logistic regression analysisRegional wall motion abnormalitiesTetrofosmin myocardial perfusion imagingLaboratory mental stressRisk of MSISerum CRP levelsHistory of diabetesSubsequent clinical eventsNew perfusion defectsWall motion abnormalitiesLogistic regression analysis
2005
Noninvasive cardiac imaging in the evaluation of suspected acute coronary syndromes
Vashist A, Abbott B. Noninvasive cardiac imaging in the evaluation of suspected acute coronary syndromes. Expert Review Of Cardiovascular Therapy 2005, 3: 473-486. PMID: 15889975, DOI: 10.1586/14779072.3.3.473.Peer-Reviewed Original ResearchConceptsChest painCoronary syndromeEmergency departmentAcute ischemiaEmission tomographyCardiac magnetic resonance imagingAcute coronary syndromeSingle photon emission tomographyAppropriate clinical settingCoronary artery diseaseReperfusion-induced cell deathImaging modalitiesRadionuclide perfusion studyNoninvasive cardiac imagingCardiac magnetic resonanceMagnetic resonance imagingPositron emission tomographyNoninvasive imaging modalityArtery diseaseSuch patientsRandomized trialsPrognostic valueDiagnostic dilemmaSubendocardial ischemiaUnnecessary hospitalization
2004
Differential impact of parasympathetic withdrawal to mental stress ischemia as assessed by noninvasive evaluation of myocardial perfusion and/or function
Vashist A, Arrighi J, Lampert R, Burg M, Soufer R. Differential impact of parasympathetic withdrawal to mental stress ischemia as assessed by noninvasive evaluation of myocardial perfusion and/or function. Journal Of Nuclear Cardiology 2004, 11: s21. DOI: 10.1016/j.nuclcard.2004.06.068.Peer-Reviewed Original ResearchChronic coronary artery diseaseRegional LV dysfunctionMyocardial ischemiaParasympathetic withdrawalLV dysfunctionChronic chronic coronary artery diseaseMental stress ischemiaRate-pressure productCoronary artery diseaseGreater parasympathetic withdrawalHigh-frequency powerStress ischemiaArtery diseaseNon-invasive imagingMPI defectsSympathovagal balanceIndividual patientsSPECT-MPIIschemiaMyocardial perfusionNoninvasive evaluationPatientsMental arithmetic taskAutonomic responsesSPECT defectsDo electrocardiographic changes with adenosine myocardial perfusion imaging predict ischaemia in patients with left ventricular hypertrophy?
Vashist A, Victoria A, Blum S, Bella J, Heller E. Do electrocardiographic changes with adenosine myocardial perfusion imaging predict ischaemia in patients with left ventricular hypertrophy? Nuclear Medicine Communications 2004, 25: 553-556. PMID: 15167513, DOI: 10.1097/01.mnm.0000126630.47661.d9.Peer-Reviewed Original ResearchMeSH KeywordsAdenosineCausalityComorbidityElectrocardiographyExercise TestFemaleHumansHypertrophy, Left VentricularIncidenceMaleMiddle AgedMyocardial IschemiaPrevalencePrognosisRadionuclide ImagingReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityStatistics as TopicUnited StatesConceptsLeft ventricular hypertrophyECG changesVentricular hypertrophyBaseline electrocardiogramElectrocardiographic changesPredictive valueSevere coronary artery diseaseEvidence of ischaemiaCoronary artery diseaseAdenosine myocardial perfusionForm of exercisePresence of collateralsNegative predictive valuePositive predictive valueArtery diseaseConsecutive patientsImaging correlatesTc-sestamibiIschaemiaMyocardial perfusionPatientsX minHypertrophyPerfusionStress test