2024
Stem Cells and Platelet-Rich Plasma in the Treatment of Osteochonndral Lesions of the Talus
Fraser E, Kennedy J, Gianakos A, Yasui Y. Stem Cells and Platelet-Rich Plasma in the Treatment of Osteochonndral Lesions of the Talus. 2024, 47-56. DOI: 10.1201/9781003524205-7.Peer-Reviewed Original ResearchPlatelet-Rich Plasma vs Extracorporeal Shock Wave Therapy in the Treatment of Plantar Fasciitis at 3-6 Months: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Daher M, Covarrubias O, Herber A, Oh I, Gianakos A. Platelet-Rich Plasma vs Extracorporeal Shock Wave Therapy in the Treatment of Plantar Fasciitis at 3-6 Months: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Foot & Ankle International 2024, 45: 796-803. PMID: 38419209, DOI: 10.1177/10711007241231959.Peer-Reviewed Original ResearchPlantar fascia thicknessExtracorporeal shock wave therapyRandomized controlled trialsPlatelet-rich plasmaPlantar fasciitisPlatelet-rich plasma groupShock wave therapyVisual analog scaleFascia thicknessControlled trialsMeta-analysisTreatment of plantar fasciitisExtracorporeal shock wave therapy groupPain scoresWave therapyVisual analog scale painMeta-analysis of randomized controlled trialsEffect of platelet-rich plasmaVAS pain scoresHigher pain reductionManagement of PFFoot disordersSystematic reviewInclusion criteriaPain reductionPlatelet rich plasma therapy versus other modalities for treatment of plantar fasciitis: A systematic review and meta-analysis
Herber A, Covarrubias O, Daher M, Tung W, Gianakos A. Platelet rich plasma therapy versus other modalities for treatment of plantar fasciitis: A systematic review and meta-analysis. Foot And Ankle Surgery 2024, 30: 285-293. PMID: 38395675, DOI: 10.1016/j.fas.2024.02.004.Peer-Reviewed Original ResearchFoot Function IndexPlantar fascia thicknessExtracorporeal shock wave therapyPlantar fasciitisRandomized controlled trialsVisual analog scaleAmerican Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot scorePlatelet-rich plasmaCause of heel painOutcome measuresFoot Function Index scoreTreatment of plantar fasciitisCorticosteroid injectionDextrose prolotherapyMean differenceAnkle-hindfoot scoreMeta-analysisPain scoresShock wave therapyFoot functionFascia thicknessHeel painMusculoskeletal conditionsTrigger pointsManagement of PF
2023
Rethinking Cartilage Lesions of the Ankle: An Update on the Role of Biologic Adjuvants
Gianakos A, Kennedy J. Rethinking Cartilage Lesions of the Ankle: An Update on the Role of Biologic Adjuvants. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 31: 701-707. PMID: 37026780, DOI: 10.5435/jaaos-d-22-01042.Peer-Reviewed Original Research
2018
Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis
Hurley E, Yasui Y, Gianakos A, Seow D, Shimozono Y, Kerkhoffs G, Kennedy J. Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis. Knee Surgery, Sports Traumatology, Arthroscopy 2018, 26: 3499-3507. PMID: 29713784, DOI: 10.1007/s00167-018-4955-x.Peer-Reviewed Original ResearchConceptsStromal vascular fractionPlatelet-rich plasmaTreatment of osteoarthritisClinical outcomesSystematic reviewForm of SVFUse of SVFAdipose-derived stem cell therapyEffects of ADSCsIncidence of swellingFavorable clinical outcomeLevel IV studiesCochrane Library databasesEffects of AdiposeDonor siteStem cell therapySVF injectionComplication rateBiological adjuvantsClinical studiesLevel IVExclusion criteriaLibrary databasesSide effectsAdipose tissue
2017
Current management of talar osteochondral lesions
Gianakos A, Yasui Y, Hannon C, Kennedy J. Current management of talar osteochondral lesions. World Journal Of Orthopedics 2017, 8: 12-20. PMID: 28144574, PMCID: PMC5241540, DOI: 10.5312/wjo.v8.i1.12.Peer-Reviewed Original ResearchAutologous osteochondral transplantationBone marrow stimulationReparative proceduresOsteochondral lesionsConcentrated bone marrow aspiratePrimary repair proceduresAcute ankle sprainsTreatment of OLTMedium-term resultsBone marrow aspirateTalar osteochondral lesionsDate clinical evidencePlatelet-rich plasmaDiagnostic imaging modalitiesAOT procedureSymptomatic OLTAdjunct therapyClinical evidenceSurgical outcomesAnkle sprainSurgical techniqueTreatment strategiesMarrow aspiratesOsteochondral transplantationLarge lesions
2015
Platelet-Rich Plasma in the Animal Long-Bone Model: An Analysis of Basic Science Evidence.
Gianakos A, Zambrana L, Savage-Elliott I, Lane J, Kennedy J. Platelet-Rich Plasma in the Animal Long-Bone Model: An Analysis of Basic Science Evidence. Orthopedics 2015, 38: e1079-90. PMID: 26652328, DOI: 10.3928/01477447-20151120-04.Peer-Reviewed Original ResearchConceptsPlatelet-rich plasmaEffect of PRPPercent of studiesLong bone modelsUse of PRPPlatelet concentrationBasic science evidencePubMed/MEDLINESignificant increaseEarly bone healingAdditional treatment variablesPeer-reviewed journalsCase seriesLong bone healingPRP groupEmbase databasesBlood productsClinical studiesHistomorphometric assessmentBone pathologyBone areaPlatelet productsBone healingBeneficial effectsVivo evidence