2018
Evidence of sinks and sources in the phospholipase C‐activated PIP2 cycle
Suratekar R, Panda A, Raghu P, Krishna S. Evidence of sinks and sources in the phospholipase C‐activated PIP2 cycle. FEBS Letters 2018, 592: 962-972. PMID: 29427502, DOI: 10.1002/1873-3468.12998.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDrosophila melanogasterDrosophila ProteinsModels, BiologicalPhosphatidylinositol 4,5-DiphosphateSignal TransductionType C Phospholipases
2015
RDGBα, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction
Yadav S, Garner K, Georgiev P, Li M, Gomez-Espinosa E, Panda A, Mathre S, Okkenhaug H, Cockcroft S, Raghu P. RDGBα, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction. Journal Of Cell Science 2015, 128: 3330-3344. PMID: 26203165, PMCID: PMC4582195, DOI: 10.1242/jcs.173476.Peer-Reviewed Original ResearchConceptsPhospholipase CPlasma membraneEndoplasmic reticulumMulti-domain proteinsPlasma membrane lipidsExchange of lipidsRdgB functionDrosophila phototransductionDrosophila photoreceptorsProtein domainsRdgB mutantsVivo functionMembrane lipidsPtdInsLipid intermediatesLipid homeostasisMembrane receptorsPLC activationPtdOH levelsTransfer proteinPhosphatidic acidPLC activityPhototransductionNormal phototransductionPtdOH