2022
Conditioned Hallucinations and Prior Overweighting Are State-Sensitive Markers of Hallucination Susceptibility
Kafadar E, Fisher VL, Quagan B, Hammer A, Jaeger H, Mourgues C, Thomas R, Chen L, Imtiaz A, Sibarium E, Negreira AM, Sarisik E, Polisetty V, Benrimoh D, Sheldon AD, Lim C, Mathys C, Powers AR. Conditioned Hallucinations and Prior Overweighting Are State-Sensitive Markers of Hallucination Susceptibility. Biological Psychiatry 2022, 92: 772-780. PMID: 35843743, PMCID: PMC10575690, DOI: 10.1016/j.biopsych.2022.05.007.Peer-Reviewed Original ResearchConceptsCH rateIncoming sensory evidenceSensory evidencePerceptual statesTask performanceComputational psychiatrySubset of participantsPrior expectationsHallucination severityBehavioral dataSymptom severityPast experienceStable measureHallucinationsPsychotic symptomsHallucination frequencyTaskSymptom expressionBayesian modelState markerHallucinatorsNonhallucinatorsOverweightingPerceptionSymptom riskPerceptual pathways to hallucinogenesis
Sheldon AD, Kafadar E, Fisher V, Greenwald MS, Aitken F, Negreira AM, Woods SW, Powers AR. Perceptual pathways to hallucinogenesis. Schizophrenia Research 2022, 245: 77-89. PMID: 35216865, PMCID: PMC9232894, DOI: 10.1016/j.schres.2022.02.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeasuring Voluntary Control Over Hallucinations: The Yale Control Over Perceptual Experiences (COPE) Scales
Mourgues C, Hammer A, Fisher V, Kafadar E, Quagan B, Bien C, Jaeger H, Thomas R, Sibarium E, Negreira AM, Sarisik E, Polisetty V, Eken H, Imtiaz A, Niles H, Sheldon AD, Powers AR. Measuring Voluntary Control Over Hallucinations: The Yale Control Over Perceptual Experiences (COPE) Scales. Schizophrenia Bulletin 2022, 48: 673-683. PMID: 35089361, PMCID: PMC9077437, DOI: 10.1093/schbul/sbab144.Peer-Reviewed Original ResearchConceptsAuditory verbal hallucinationsPositive clinical outcomesClinical outcomesPilot studyQuality of lifeConvergent validityFrequent auditory verbal hallucinationsExperiences ScaleClinical measuresConventional treatmentNovel interventionsSymptom severitySignificant distressClinical scalesComprehensive batteryPsychosis-spectrum diagnosisVerbal hallucinationsSound psychometric propertiesAVH contentVoluntary controlPsychometric propertiesHallucinationsControl ScaleValidation studyIntervention
2021
Computational Mechanism for the Effect of Psychosis Community Treatment: A Conceptual Review From Neurobiology to Social Interaction
Benrimoh D, Sheldon A, Sibarium E, Powers AR. Computational Mechanism for the Effect of Psychosis Community Treatment: A Conceptual Review From Neurobiology to Social Interaction. Frontiers In Psychiatry 2021, 12: 685390. PMID: 34385938, PMCID: PMC8353084, DOI: 10.3389/fpsyt.2021.685390.Peer-Reviewed Original ResearchComputational modelAssertive community treatmentProcessing-based accountExperience of psychosisEvidence-based clinical interventionsCommunity treatmentPrevious computational modelsCognitive resourcesPositive psychotic symptomsComputational underpinningsComputational mechanismsSocial interactionStrong social elementSensory informationPositive symptomsConceptual reviewClinical interventionsEarly psychosisSocial elementsCandidate mechanismPsychotic symptomsNeurobiologyPsychosisConceptual paperMultiple levels