2024
VEXAS Syndrome: Histiocytoid Cells With Feathery Cytoplasm as a Clue to the Diagnosis
Ko C, Odell I, Gehlhausen J, Leventhal J, McNiff J, Zubek A. VEXAS Syndrome: Histiocytoid Cells With Feathery Cytoplasm as a Clue to the Diagnosis. Journal Of Cutaneous Pathology 2024 PMID: 39610062, DOI: 10.1111/cup.14757.Peer-Reviewed Original ResearchIsolated single or pauci-nail lichen planus, three cases
Jiang R, Kim R, Christensen S, Zubek A. Isolated single or pauci-nail lichen planus, three cases. JAAD Case Reports 2024, 46: 52-56. PMID: 38510835, PMCID: PMC10951446, DOI: 10.1016/j.jdcr.2024.01.031.Peer-Reviewed Original ResearchRapidly progressive subungual gray-brown melanonychia
Echeandia-Francis C, Nock M, Myung P, Zubek A. Rapidly progressive subungual gray-brown melanonychia. JAAD Case Reports 2024, 44: 113-115. PMID: 38414828, PMCID: PMC10897537, DOI: 10.1016/j.jdcr.2024.01.013.Peer-Reviewed Original Research
2022
Extensive blaschkoid macules and patches since birth
Xu S, Ellis K, Roy S, Johnston M, Zubek A. Extensive blaschkoid macules and patches since birth. JAAD Case Reports 2022, 31: 59-61. PMID: 36505037, PMCID: PMC9731867, DOI: 10.1016/j.jdcr.2022.10.030.Peer-Reviewed Original ResearchPruritic annular erythematous eruption after receiving the COVID-19 vaccine
Cross DE, Garritano J, Zubek AE, Little AJ. Pruritic annular erythematous eruption after receiving the COVID-19 vaccine. International Journal Of Women's Dermatology 2022, 8: e033. PMID: 35837337, PMCID: PMC9276362, DOI: 10.1097/jw9.0000000000000033.Peer-Reviewed Case Reports and Technical NotesTender violaceous nodule on the palm
Jiang R, Kim R, Panse G, Zubek A. Tender violaceous nodule on the palm. JAAD Case Reports 2022, 24: 42-44. PMID: 35600570, PMCID: PMC9119823, DOI: 10.1016/j.jdcr.2022.01.039.Peer-Reviewed Case Reports and Technical Notes
2021
Subungual neuroma masquerading as green nail syndrome
Choi R, Kim R, Glusac EJ, Zubek A. Subungual neuroma masquerading as green nail syndrome. JAAD Case Reports 2021, 20: 17-19. PMID: 35024402, PMCID: PMC8728514, DOI: 10.1016/j.jdcr.2021.11.025.Peer-Reviewed Original ResearchThe LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation
Carley E, Stewart R, Zieman AG, Jalilian I, King DE, Zubek AE, Lin S, Horsley V, King MC. The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation. ELife 2021, 10: e58541. PMID: 33779546, PMCID: PMC8051949, DOI: 10.7554/elife.58541.Peer-Reviewed Original ResearchConceptsCell fateEpidermal cell fateLinker of nucleoskeletonCell fate decisionsEpidermal differentiation genesEpidermal differentiationDirect force transmissionEpidermal stem cellsCytoskeleton (LINC) complexLINC complexFate decisionsNuclear laminaType laminsDifferentiation genesIntegrin engagementForce transductionDifferentiation concomitantChemical signalsMechanotransduction pathwaysKeratinocyte progenitorsMolecular biosensorsStem cellsKeratinocyte differentiationDifferentiationMechanical input
2020
Onychodystrophy associated with dupilumab therapy for atopic dermatitis
Zubek AE, Vesely MD. Onychodystrophy associated with dupilumab therapy for atopic dermatitis. JAAD Case Reports 2020, 7: 20-22. PMID: 33318995, PMCID: PMC7727284, DOI: 10.1016/j.jdcr.2020.10.024.Peer-Reviewed Case Reports and Technical NotesPink plaques on the face of an adolescent male
Gehlhausen JR, Myung P, Zubek A. Pink plaques on the face of an adolescent male. International Journal Of Dermatology 2020, 60: e217-e218. PMID: 33084046, DOI: 10.1111/ijd.15265.Peer-Reviewed Original ResearchA rare case of lupoid leishmaniasis defying diagnosis for a decade
Gehlhausen J, Sibindi C, Ko CJ, Grant M, Zubek A. A rare case of lupoid leishmaniasis defying diagnosis for a decade. Journal Of Cutaneous Pathology 2020, 47: 1054-1057. PMID: 32623733, DOI: 10.1111/cup.13793.Peer-Reviewed Case Reports and Technical NotesConceptsCutaneous leishmaniasisGranulomatous rosaceaPolymerase chain reactionFacial plaquesLupoid leishmaniasisMultiple medical therapiesAcid-fast bacilliExtensive travel historyStandard histopathologic examinationMedical therapyNew lesionsMultiple biopsiesRare presentationHistopathologic examinationGranulomatous diseaseTuberculoid granulomasUltimate diagnosisRare caseSustained improvementEndemic areasSpecial stainsTravel historySarcoidosisCommon diseaseRosaceaDevelopment or worsening of sarcoidosis associated with IL‐17 blockade for psoriasis
Hornick N, Wang A, Lim Y, Gehlhausen J, Siegel J, Wang J, Foss F, Lim I, Zubek A, Milstone L, Galan A, King B, Damsky W. Development or worsening of sarcoidosis associated with IL‐17 blockade for psoriasis. Journal Of The European Academy Of Dermatology And Venereology 2020, 34: e583-e585. PMID: 32277505, DOI: 10.1111/jdv.16451.Peer-Reviewed Case Reports and Technical NotesInterleukin‐17 blockade downregulates NOD2 in skin and may promote paradoxical sarcoidosis
Wang A, Hornick N, Lim Y, Gehlhausen J, Siegel J, Wang J, Foss F, Lim I, Zubek A, Milstone L, Galan A, King B, Damsky W. Interleukin‐17 blockade downregulates NOD2 in skin and may promote paradoxical sarcoidosis. Journal Of The European Academy Of Dermatology And Venereology 2020, 34: e497-e499. PMID: 32249470, DOI: 10.1111/jdv.16416.Peer-Reviewed Case Reports and Technical Notes
2018
Maggot therapy for calciphylaxis wound debridement complicated by bleeding
Shih AF, Little AJ, Panse G, Liu J, Yiu G, Yaggi HK, Zubek A. Maggot therapy for calciphylaxis wound debridement complicated by bleeding. JAAD Case Reports 2018, 4: 396-398. PMID: 29693082, PMCID: PMC5911942, DOI: 10.1016/j.jdcr.2018.01.011.Peer-Reviewed Case Reports and Technical Notes
2017
Balanitis associated with FOLFIRI chemotherapy
Micevic G, Perkins SH, Zubek AE. Balanitis associated with FOLFIRI chemotherapy. JAAD Case Reports 2017, 4: 58-60. PMID: 29387750, PMCID: PMC5771729, DOI: 10.1016/j.jdcr.2017.09.001.Peer-Reviewed Original Research
2016
Painless Vesicular Eruption on the Dorsal Surfaces of the Hands
Shih A, Damsky W, Zubek A. Painless Vesicular Eruption on the Dorsal Surfaces of the Hands. JAMA 2016, 316: 1312-1313. PMID: 27673309, DOI: 10.1001/jama.2016.11260.Peer-Reviewed Original ResearchRevisiting histopathologic findings in Goltz syndrome
Ko CJ, Antaya RJ, Zubek A, Craiglow B, Damsky W, Galan A, McNiff JM. Revisiting histopathologic findings in Goltz syndrome. Journal Of Cutaneous Pathology 2016, 43: 418-421. PMID: 26956940, DOI: 10.1111/cup.12699.Peer-Reviewed Original ResearchSomatic Mosaicism in Blaschkolinear Inflammatory Disorders
Theodosakis N, Levy L, Cowper S, Lazova R, Kugelman L, Zubek A, Choate K. Somatic Mosaicism in Blaschkolinear Inflammatory Disorders. Journal Of Clinical & Experimental Dermatology Research 2016, 2016: 1000356. PMID: 36267522, PMCID: PMC9581078, DOI: 10.4172/2155-9554.1000356.Peer-Reviewed Case Reports and Technical NotesDiscoid lupus erythematosusLinear lichen planusLupus erythematosusLichen planusBlaschko's linesModerate symptomatic benefitRare dermatologic diseaseRelevant therapeutic targetSomatic mosaicismBlaschkolinear distributionSymptomatic benefitTopical steroidsCutaneous manifestationsLP patientsLichenoid lesionsDLE patientsInflammatory disordersInflammatory diseasesEfficacious therapyDermatologic diseasesInflammatory reactionEpidermal nevusLinear lesionsNevus sebaceusTherapeutic target
2015
Nuclear–cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions
Stewart RM, Zubek AE, Rosowski KA, Schreiner SM, Horsley V, King MC. Nuclear–cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions. Journal Of Cell Biology 2015, 209: 403-418. PMID: 25963820, PMCID: PMC4427780, DOI: 10.1083/jcb.201502024.Peer-Reviewed Original ResearchConceptsIntercellular adhesionNuclear positionEpidermal tissue integrityLinker of nucleoskeletonCross talkPrimary mouse keratinocytesCytoskeleton (LINC) complexCytoplasmic cytoskeletonAdhesion functionMicrotubule networkDefective adhesionCytoskeletonSUN2Mouse keratinocytesTissue integrityFollicle structureEpidermal keratinocytesAdhesionNucleoskeletonCellsKeratinocytesAdhesion formationNucleusIntegrityComplexes