2023
Brain Networks and Adolescent Alcohol Use
Yip S, Lichenstein S, Liang Q, Chaarani B, Dager A, Pearlson G, Banaschewski T, Bokde A, Desrivières S, Flor H, Grigis A, Gowland P, Heinz A, Brühl R, Martinot J, Martinot M, Artiges E, Nees F, Orfanos D, Paus T, Poustka L, Hohmann S, Millenet S, Fröhner J, Smolka M, Vaidya N, Walter H, Whelan R, Schumann G, Garavan H. Brain Networks and Adolescent Alcohol Use. JAMA Psychiatry 2023, 80: 1131-1141. PMID: 37647053, PMCID: PMC10469292, DOI: 10.1001/jamapsychiatry.2023.2949.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestAlcohol use riskAlcohol misuseUse riskAlcohol use disorderMale adolescentsDisorders Identification TestSingle-site studyIntervention effortsWhole-brain patternsMean ageAlcohol use dataLeading causeMagnetic resonance imaging dataMAIN OUTCOMEReward-related processesHigh riskSeparate cohortUse disordersAlcohol consumptionCurrent severityAdolescent neurodevelopmentAlcohol use behaviorsAlcohol useAUDIT scores
2017
Effects of Drinking Patterns on Prospective Memory Performance in College Students
Zamroziewicz M, Raskin SA, Tennen H, Austad CS, Wood RM, Fallahi CR, Dager AD, Sawyer B, Leen S, Pearlson GD. Effects of Drinking Patterns on Prospective Memory Performance in College Students. Neuropsychology 2017, 31: 191-199. PMID: 27841457, PMCID: PMC5280574, DOI: 10.1037/neu0000313.Peer-Reviewed Original ResearchConceptsAlcohol Effects QuestionnaireProspective memoryAlcohol-induced amnesiaPM taskRetrospective memoryTimeline Follow-BackCollege studentsMemory testingEvent-based PM taskTime-based PM taskMeasures of PMTime-based prospective memoryAlcohol useFourth-year college studentsYear college studentsPM itemsRM taskHeavy drinkersConsequences ScaleEffects of alcoholParticipants' abilityMental Disorders-Fourth EditionRM performanceHeavy alcohol useTraditional college students
2015
A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers
Worhunsky PD, Dager AD, Meda SA, Khadka S, Stevens MC, Austad CS, Raskin SA, Tennen H, Wood RM, Fallahi CR, Potenza MN, Pearlson GD. A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers. Neuropsychopharmacology 2015, 41: 1637-1647. PMID: 26514582, PMCID: PMC4832027, DOI: 10.1038/npp.2015.332.Peer-Reviewed Original ResearchConceptsAlcohol useYoung adult drinkersYoung adultsPreliminary prospective studyAdult drinkersExcessive alcohol useAlcohol use disorderFunctional network activityProspective studyUse disordersFunctional brain networksGo/No-Go taskNeurobiological alterationsDomain scoresGreater riskDaily drinksAddictive disordersDrinkersDrinking occasionsLongitudinal studyFronto-parietal circuitryBrain networks
2014
On the Mismeasurement of Impulsivity: Trait, Behavioral, and Neural Models in Alcohol Research among Adolescents and Young Adults
King K, Patock-Peckham J, Dager A, Thimm K, Gates J. On the Mismeasurement of Impulsivity: Trait, Behavioral, and Neural Models in Alcohol Research among Adolescents and Young Adults. Current Addiction Reports 2014, 1: 19-32. DOI: 10.1007/s40429-013-0005-4.Peer-Reviewed Original ResearchBehavioral impulsivityTrait modelNeural modelDefinition of impulsivityShared theoretical frameworkTwo-factor modelAlcohol use riskAlcohol researchEmotion dysregulationEffortful controlImpulsigenic traitsImpulsive choiceMotivational driveDevelopmental researchImpulsivityPsychosocial traitsDevelopmental modelYoung adulthoodBehavioral researchAlcohol useGeneral underrepresentationYoung adultsEmpirical connectionUse riskBehavioral model
2013
Influence of Alcohol Use on Neural Response to Go/No-Go Task in College Drinkers
Ahmadi A, Pearlson GD, Meda SA, Dager A, Potenza MN, Rosen R, Austad CS, Raskin SA, Fallahi CR, Tennen H, Wood RM, Stevens MC. Influence of Alcohol Use on Neural Response to Go/No-Go Task in College Drinkers. Neuropsychopharmacology 2013, 38: 2197-2208. PMID: 23670589, PMCID: PMC3773670, DOI: 10.1038/npp.2013.119.Peer-Reviewed Original ResearchConceptsSupplementary motor areaHeavy drinkersLight drinkersCollege-age drinkersAlcohol useResponse inhibitionBlood oxygen level-dependent (BOLD) responseHeavy alcohol drinkersImportant risk factorBilateral middle frontal gyrusAlcohol use disorderBrain activityAnterior cingulate cortexGreater BOLD responseLevel-dependent responsesMiddle frontal gyrusSuperior temporal gyrusImpaired response inhibitionAlcohol drinkersRisk factorsResponse inhibition taskRight hippocampusMotor areaWarrants additional investigationBilateral parietal lobules