2021
Racial Disparities in Health Care Resource Utilization After Pediatric Cervical and/or Thoracic Spinal Injuries
Elsamadicy AA, Sandhu MR, Freedman IG, Koo AB, Hengartner AC, Reeves BC, Havlik J, Sarkozy M, Hong CS, Kundishora AJ, Tuason DA, DiLuna M. Racial Disparities in Health Care Resource Utilization After Pediatric Cervical and/or Thoracic Spinal Injuries. World Neurosurgery 2021, 156: e307-e318. PMID: 34560297, DOI: 10.1016/j.wneu.2021.09.047.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAsianBlack or African AmericanCervical VertebraeChildChild, PreschoolCohort StudiesFemaleHealth Status DisparitiesHealthcare DisparitiesHispanic or LatinoHumansInfantLength of StayMalePostoperative ComplicationsRetrospective StudiesSocioeconomic FactorsSpinal InjuriesThoracic VertebraeUnited StatesWhite PeopleConceptsHealth care resource utilizationNon-Hispanic blacksNon-Hispanic AsiansHospital complicationsPediatric patientsMultivariate regression analysisNon-Hispanic whitesHospital LOSComplication rateGreater prevalenceICD-10-CM diagnosisLogistic multivariate regression analysisNational Trauma Data BankLonger hospital LOSOverall complication rateThoracic spine injuriesTrauma Data BankRegression analysisThoracic spinal injuryNHB patientsHospital lengthRetrospective cohortSpine injuriesThoracic injuriesRisk ratioImpact of Frailty on Morbidity and Mortality in Adult Patients Presenting with an Acute Traumatic Cervical Spinal Cord Injury
Elsamadicy AA, Sandhu MRS, Freedman IG, Reeves BC, Koo AB, Hengartner A, Havlik J, Sherman J, Maduka R, Agboola IK, Johnson DC, Kolb L, Laurans M. Impact of Frailty on Morbidity and Mortality in Adult Patients Presenting with an Acute Traumatic Cervical Spinal Cord Injury. World Neurosurgery 2021, 153: e408-e418. PMID: 34224881, DOI: 10.1016/j.wneu.2021.06.130.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCervical CordCohort StudiesComorbidityFemaleFrailtyHumansMaleMiddle AgedRetrospective StudiesSpinal Cord InjuriesConceptsCervical spinal cord injurySpinal cord injuryAcute cervical spinal cord injuryNational Trauma DatabaseAdverse eventsHospital mortalityFrailty scoreAdult patientsIndependent predictorsCord injuryAcute traumatic cervical spinal cord injuryTraumatic cervical spinal cord injuryRisk of AEsComplete spinal cord injuryMultivariate logistic regression analysisCentral cord syndromeHospital adverse eventsImpact of frailtyRetrospective cohort studyProportion of patientsType of injuryProcedural Coding SystemLogistic regression analysisRegression analysisMultivariate regression analysisIndependent Association of Obesity and Nonroutine Discharge Disposition After Elective Anterior Cervical Discectomy and Fusion for Cervical Spondylotic Myelopathy
Koo AB, Elsamadicy AA, Sarkozy M, David WB, Reeves BC, Hong CS, Boylan A, Laurans M, Kolb L. Independent Association of Obesity and Nonroutine Discharge Disposition After Elective Anterior Cervical Discectomy and Fusion for Cervical Spondylotic Myelopathy. World Neurosurgery 2021, 151: e950-e960. PMID: 34020060, DOI: 10.1016/j.wneu.2021.05.022.Peer-Reviewed Original ResearchConceptsCervical spondylotic myelopathyNonroutine discharge dispositionAnterior cervical discectomyElective anterior cervical discectomyDischarge dispositionSpondylotic myelopathyCervical discectomyElective ACDFComplication rateNational Inpatient Sample databaseElective spine surgeryOverall complication ratePrevalence of obesityShort-term outcomesLength of stayHospital bed sizeMultivariate regression analysisHealth care coverageMore comorbiditiesNonroutine dischargeDischarge weightIndependent predictorsElixhauser comorbiditiesGreater proportionPrimary diagnosisRace Is an Independent Predictor for Nonroutine Discharges After Spine Surgery for Spinal Intradural/Cord Tumors
Elsamadicy AA, Koo AB, David WB, Reeves BC, Freedman IG, Pennington Z, Ehresman J, Kolb L, Laurans M, Shin JH, Sciubba DM. Race Is an Independent Predictor for Nonroutine Discharges After Spine Surgery for Spinal Intradural/Cord Tumors. World Neurosurgery 2021, 151: e707-e717. PMID: 33940256, DOI: 10.1016/j.wneu.2021.04.085.Peer-Reviewed Original ResearchConceptsNonroutine discharge dispositionIndependent predictorsNonroutine dischargeDischarge dispositionCord tumorsAA raceSurgical interventionNational Inpatient Sample databaseMultivariable logistic regression analysisStepwise multivariable logistic regression analysisBackward stepwise multivariable logistic regression analysisAfrican AmericansPostoperative complication rateRetrospective cohort studyClinical Modification diagnosisLength of hospitalizationProcedural Coding SystemLogistic regression analysisHealth care costsRegression analysisMultivariate regression analysisAA/BlackPostoperative complicationsCohort studyComplication ratePatient Risk Factors Associated With 30- and 90-Day Readmission After Ventriculoperitoneal Shunt Placement for Idiopathic Normal Pressure Hydrocephalus in Elderly Patients: A Nationwide Readmission Study
Koo AB, Elsamadicy AA, Lin IH, David WB, Reeves BC, Santarosa C, Cord B, Malhotra A, Kahle KT, Matouk CC. Patient Risk Factors Associated With 30- and 90-Day Readmission After Ventriculoperitoneal Shunt Placement for Idiopathic Normal Pressure Hydrocephalus in Elderly Patients: A Nationwide Readmission Study. World Neurosurgery 2021, 152: e23-e31. PMID: 33862298, DOI: 10.1016/j.wneu.2021.04.010.Peer-Reviewed Original ResearchConceptsIdiopathic normal pressure hydrocephalusVP shunt surgeryShunt surgeryElderly patientsNormal pressure hydrocephalusPressure hydrocephalusNationwide Readmissions DatabaseVentriculoperitoneal shunt surgeryPatient risk factorsVentriculoperitoneal shunt placementQuality of careMultivariate regression analysisIndex admissionUnplanned readmissionReadmission ratesRenal failureMechanical complicationsPostoperative infectionShunt placementNinth RevisionFemale sexRisk factorsSubdural hemorrhageClinical ModificationReadmissionPost-traumatic seizures following pediatric traumatic brain injury
Elsamadicy AA, Koo AB, David WB, Lee V, Zogg CK, Kundishora AJ, Hong C, Reeves BC, Sarkozy M, Kahle KT, DiLuna M. Post-traumatic seizures following pediatric traumatic brain injury. Clinical Neurology And Neurosurgery 2021, 203: 106556. PMID: 33636505, DOI: 10.1016/j.clineuro.2021.106556.Peer-Reviewed Original ResearchConceptsLoss of consciousnessTraumatic brain injuryPost-traumatic seizuresSeizure developmentBrain injuryRisk factorsPre-existing medical comorbiditiesPediatric traumatic brain injuryClinical risk factorsDevelopment of seizuresRate of seizuresDecrease healthcare costsEtiology of injuryType of injuryLogistic regression analysisQuality of careHospital complicationsMedical comorbiditiesNeurological complicationsPediatric patientsTBI patientsGreater proportionNinth RevisionSubarachnoid hemorrhageSecondary diagnosis
2020
Impact of Preoperative Anemia on Outcomes After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis
Elsamadicy AA, Freedman IG, Koo AB, David WB, Havlik J, Kundishora AJ, Hong CS, Sciubba DM, Kahle KT, DiLuna M. Impact of Preoperative Anemia on Outcomes After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. World Neurosurgery 2020, 146: e214-e224. PMID: 33091648, DOI: 10.1016/j.wneu.2020.10.074.Peer-Reviewed Original ResearchConceptsPosterior spinal fusionAdolescent idiopathic scoliosisPreoperative anemiaAnemic cohortHospital stayReadmission ratesIndependent predictorsSpinal fusionIdiopathic scoliosisNational Surgical Quality Improvement Program Pediatric databaseSurgeons National Surgical Quality Improvement Program Pediatric databaseUnplanned reoperation rateLonger hospital stayRetrospective cohort studyThirty-day outcomesLonger operative timeLonger lengthPostoperative complicationsReoperation rateCohort studyDischarge dispositionComplication ratePediatric patientsTransfusion eventsOperative timePortending Influence of Racial Disparities on Extended Length of Stay after Elective Anterior Cervical Discectomy and Interbody Fusion for Cervical Spondylotic Myelopathy
Elsamadicy AA, Koo AB, David WB, Sarkozy M, Freedman IG, Reeves BC, Laurans M, Kolb L, Sciubba DM. Portending Influence of Racial Disparities on Extended Length of Stay after Elective Anterior Cervical Discectomy and Interbody Fusion for Cervical Spondylotic Myelopathy. World Neurosurgery 2020, 142: e173-e182. PMID: 32599203, DOI: 10.1016/j.wneu.2020.06.155.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanCerebrospinal Fluid LeakCervical VertebraeCohort StudiesComorbidityDiskectomyElective Surgical ProceduresFemaleHealthcare DisparitiesHumansIntraoperative ComplicationsLength of StayMaleMiddle AgedPostoperative ComplicationsPrevalenceRetrospective StudiesSpinal Cord CompressionSpinal FusionSpondylosisUnited StatesWhite PeopleConceptsCervical spondylotic myelopathyElective anterior cervical discectomyAnterior cervical discectomyAA cohortSpondylotic myelopathyCervical discectomyExtended LOSC cohortSignificant independent risk factorsNational Inpatient Sample databaseLonger hospital stayPrevalence of comorbiditiesRetrospective cohort studyIndependent risk factorNumber of complicationsAfrican AmericansElective ACDFNonroutine dischargeAA raceC patientsHospital stayAdult patientsCohort studyIndependent predictorsAA patientsRisk Factors for the Development of Post-Traumatic Hydrocephalus in Children
Elsamadicy AA, Koo AB, Lee V, David WB, Zogg CK, Kundishora AJ, Hong CS, DeSpenza T, Reeve BC, DiLuna M, Kahle KT. Risk Factors for the Development of Post-Traumatic Hydrocephalus in Children. World Neurosurgery 2020, 141: e105-e111. PMID: 32389871, PMCID: PMC7484270, DOI: 10.1016/j.wneu.2020.04.216.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryRisk factorsBrain injuryNationwide Emergency Department Sample databasePost-traumatic hydrocephalusClinical risk factorsDevelopment of hydrocephalusNeurologic complicationsRespiratory complicationsPediatric patientsHydrocephalus developmentNinth RevisionSubarachnoid hemorrhageEmergency departmentSecondary diagnosisPrimary diagnosisSubdural hemorrhageClinical ModificationInternational ClassificationHydrocephalusHemorrhagePatientsBaseline returnSample databaseAge 6Associated risk factors for extended length of stay following anterior cervical discectomy and fusion for cervical spondylotic myelopathy
Elsamadicy AA, Koo AB, Lee M, David WB, Kundishora AJ, Robert SM, Kuzmik GA, Coutinho PO, Kolb L, Laurans M, Abbed K. Associated risk factors for extended length of stay following anterior cervical discectomy and fusion for cervical spondylotic myelopathy. Clinical Neurology And Neurosurgery 2020, 195: 105883. PMID: 32428797, DOI: 10.1016/j.clineuro.2020.105883.Peer-Reviewed Original ResearchConceptsCervical spondylotic myelopathyHospital-level factorsLOS cohortAnterior cervical discectomyExtended LOSMultivariate logistic regressionSpondylotic myelopathyPostoperative complicationsCervical discectomyBlood transfusionOdds ratioNational Inpatient Sample databaseLogistic regressionFurther investigational studiesOverall complication rateNon-routine dischargeAssociated risk factorsNational cohort studyNumber of complicationsRisk-adjusted LOSGreater overall costsLow socioeconomic statusPaucity of literatureHospital LOSHospital stayInfluence of gender on discharge disposition after spinal fusion for adult spine deformity correction
Elsamadicy AA, Freedman IG, Koo AB, David WB, Lee M, Kundishora AJ, Kuzmik GA, Gorrepati R, Hong CS, Kolb L, Laurans M, Abbed K. Influence of gender on discharge disposition after spinal fusion for adult spine deformity correction. Clinical Neurology And Neurosurgery 2020, 194: 105875. PMID: 32388244, DOI: 10.1016/j.clineuro.2020.105875.Peer-Reviewed Original ResearchConceptsDischarge dispositionSpine deformity correctionSpinal fusionFemale cohortMale cohortDeformity correctionElective spine fusion surgeryNon-routine discharge dispositionNationwide Inpatient Sample databaseSpine surgical careSurgical site hematomaNon-routine dischargeElective spinal fusionICD-9 codesSpine fusion surgeryInfluence of genderPostoperative MIPostoperative UTIHospital staySite hematomaHospital factorsIndependent predictorsMale patientsFemale patientsFusion surgeryIndependent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction.
Elsamadicy AA, Adil SM, Charalambous L, Drysdale N, Koo AB, Lee M, Kundishora AJ, Camara-Quintana J, Kolb L, Laurans M, Abbed K, Karikari IO. Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction. Spine 2020, 45: 268-274. PMID: 31996654, DOI: 10.1097/brs.0000000000003260.Peer-Reviewed Original ResearchConceptsIntraoperative blood transfusionComplex spinal fusionAllogenic blood transfusionPostoperative deliriumBlood transfusionSpinal fusionIndependent associationDeformity correctionMultivariate nominal-logistic regression analysisPrimary complex spinal fusionAdult spine deformity patientsAdult deformity correctionBetter overall patient careGreater complication risksRetrospective cohort studySpine deformity patientsOverall patient careNominal logistic regression analysisMajor academic institutionHospital stayCohort studyBlood lossPrimary outcomeComplication riskDeformity patients
2018
Prevalence and Cost Analysis of Chronic Pain After Hernia Repair: A Potential Alternative Approach With Neurostimulation
Elsamadicy AA, Ashraf B, Ren X, Sergesketter AR, Charalambous L, Kemeny H, Ejikeme T, Yang S, Pagadala P, Parente B, Xie J, Pappas TN, Lad SP. Prevalence and Cost Analysis of Chronic Pain After Hernia Repair: A Potential Alternative Approach With Neurostimulation. Neuromodulation Technology At The Neural Interface 2018, 22: 960-969. PMID: 30320933, PMCID: PMC6465156, DOI: 10.1111/ner.12871.Peer-Reviewed Original ResearchConceptsChronic painInpatient/outpatientHernia repairPrescription costsCP cohortOutpatient costsIndex hernia repairPrevalence of CPChronic pain cohortHealthcare resource utilizationHealth care utilizationCurrent treatment paradigmsRetrospective longitudinal studyYears of ageLongitudinal multivariate analysisNonopioid treatmentPain prescriptionsCP diagnosisPain cohortCare utilizationDiagnosis yearTruven MarketScanPain diagnosisTreatment paradigmInclusion criteriaIndependent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients.
Elsamadicy AA, Ren X, Kemeny H, Charalambous L, Sergesketter AR, Rahimpour S, Williamson T, Goodwin CR, Abd-El-Barr MM, Gottfried ON, Xie J, Lad SP. Independent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients. Neurosurgery 2018, 84: 758-767. PMID: 29893899, DOI: 10.1093/neuros/nyy215.Peer-Reviewed Original ResearchConceptsElective lumbar spine surgeryChronic obstructive pulmonary disorderLumbar spine surgeryNational Readmission DatabaseUnplanned hospital readmissionPatient risk factorsUnplanned readmissionHospital readmissionSpine surgeryDeficiency anemiaInsurance statusRisk factorsElective spinal surgeryUnplanned readmission rateObstructive pulmonary disorderMultivariate regression analysisPaucity of dataInpatient complicationsNational healthcare expendituresReadmission ratesDural tearPulmonary disordersIndependent associationPatient outcomesSpinal surgeryMinimally Invasive Lateral Access Surgery and Reoperation Rates: A Multi-Institution Retrospective Review of 2060 Patients
Nayar G, Wang T, Sankey EW, Berry-Candelario J, Elsamadicy AA, Back A, Karikari I, Isaacs R. Minimally Invasive Lateral Access Surgery and Reoperation Rates: A Multi-Institution Retrospective Review of 2060 Patients. World Neurosurgery 2018, 116: e744-e749. PMID: 29787875, DOI: 10.1016/j.wneu.2018.05.082.Peer-Reviewed Original ResearchConceptsRate of reoperationLateral access surgeryLumbar spine surgeryMore comorbiditiesSurgical approachSpine surgeryDecompressive lumbar spine surgeryElective lumbar spinal surgeryMulti-institution retrospective reviewAccess surgeryLower body mass indexLumbar spinal surgeryBody mass indexOpen posterior approachHealth care systemOnly significant predictorAdditional readmissionsLT cohortOP cohortOP surgeryReoperation ratePatient demographicsSurgical complicationsRetrospective reviewMass indexInterdisciplinary Care Model Independently Decreases Use of Critical Care Services After Corrective Surgery for Adult Degenerative Scoliosis
Adogwa O, Elsamadicy AA, Sergesketter AR, Ongele M, Vuong V, Khalid S, Moreno J, Cheng J, Karikari IO, Bagley CA. Interdisciplinary Care Model Independently Decreases Use of Critical Care Services After Corrective Surgery for Adult Degenerative Scoliosis. World Neurosurgery 2018, 111: e845-e849. PMID: 29317368, DOI: 10.1016/j.wneu.2017.12.180.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCase ManagementClinical ProtocolsCohort StudiesCritical CareDecompression, SurgicalFemaleGeriatricsHumansLumbar VertebraeMaleNeurosurgical ProceduresPatient Care TeamPostoperative CarePostoperative ComplicationsRetrospective StudiesScoliosisSpinal FusionTreatment OutcomeConceptsElderly patientsCritical care servicesICU transferIndependent predictorsCorrective surgeryFusion surgeryComanagement modelSpine surgeryCare servicesComplex lumbar spine surgeryTeam approachIntensive care unit resourcesPeri-operative optimizationSenior Health (POSH) programDuration of surgeryLumbar spine surgeryInterdisciplinary care modelLong-term outcomesLumbar fusion surgeryMajor academic medical centerAdult degenerative scoliosisAcademic medical centerInterdisciplinary team approachPOSH cohortHospital course
2017
Institutional Review of Mortality in 5434 Consecutive Neurosurgery Patients: Are We Improving?
Elsamadicy AA, Sergesketter A, Sampson JH, Gottfried ON. Institutional Review of Mortality in 5434 Consecutive Neurosurgery Patients: Are We Improving? Neurosurgery 2017, 83: 1269-1276. PMID: 29300938, DOI: 10.1093/neuros/nyx603.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesHumansMaleNeurosurgeryNeurosurgical ProceduresQuality ImprovementQuality Indicators, Health CareConceptsRisk of mortalityCase mix indexSeverity of illnessPostintervention cohortMortality indexQuality InitiativeNeurosurgical serviceDiagnosis-related group codesPre-intervention cohortQuality improvement interventionsEtiology of mortalityHigher case mix indexMajor academic institutionHospital dischargeInpatient mortalityTrauma admissionsNeurosurgery patientsProcedure typeMortality casesInstitutional reviewImprovement interventionsMortalityCohortNeurosurgery inpatientsObserved mortalityDrivers and Risk Factors of Unplanned 30‐Day Readmission Following Spinal Cord Stimulator Implantation
Elsamadicy AA, Sergesketter A, Ren X, Hussaini S, Laarakker A, Rahimpour S, Ejikeme T, Yang S, Pagadala P, Parente B, Xie J, Lad SP. Drivers and Risk Factors of Unplanned 30‐Day Readmission Following Spinal Cord Stimulator Implantation. Neuromodulation Technology At The Neural Interface 2017, 21: 87-92. PMID: 28961362, PMCID: PMC5766416, DOI: 10.1111/ner.12689.Peer-Reviewed Original ResearchConceptsSpinal cord stimulator implantationSCS implantationUnplanned readmissionIndependent predictorsPatient demographicsReadmission ratesMechanical complicationsStimulator implantationBaseline patient demographicsNational Readmission DatabaseReadmission statusNational healthcare expendituresPrimary outcomeHospital characteristicsRisk factorsPatient outcomesReadmissionMultivariate analysisPatientsSCS deviceHealthcare expendituresComorbiditiesImplantationComplicationsObesityEarly Ambulation Decreases Length of Hospital Stay, Perioperative Complications and Improves Functional Outcomes in Elderly Patients Undergoing Surgery for Correction of Adult Degenerative Scoliosis
Adogwa O, Elsamadicy AA, Fialkoff J, Cheng J, Karikari IO, Bagley C. Early Ambulation Decreases Length of Hospital Stay, Perioperative Complications and Improves Functional Outcomes in Elderly Patients Undergoing Surgery for Correction of Adult Degenerative Scoliosis. Spine 2017, 42: 1420-1425. PMID: 28902101, DOI: 10.1097/brs.0000000000002189.Peer-Reviewed Original ResearchMeSH KeywordsAgedCohort StudiesEarly AmbulationHumansLength of StayPostoperative ComplicationsScoliosisTreatment OutcomeConceptsAdult degenerative scoliosisElderly patientsPerioperative complicationsHospital stayUnplanned readmissionReadmission ratesComplication rateInhospital stayDegenerative scoliosisFunctional outcomeDays of immobilityHospital-associated complicationsDays of dischargeElective spinal surgeryHours of surgeryInferior functional outcomesMajority of patientsHigh complication rateEarly ambulationNonsurgical complicationsAmbispective studyBaseline characteristicsCohort reviewDecrease lengthEarly mobilizationImpact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients
Elsamadicy AA, Reddy GB, Nayar G, Sergesketter A, Zakare-Fagbamila R, Karikari IO, Gottfried ON. Impact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients. World Neurosurgery 2017, 107: 952-958. PMID: 28743671, DOI: 10.1016/j.wneu.2017.07.082.Peer-Reviewed Original ResearchConceptsElective lumbar spine surgeryLumbar spine surgeryVisual analog scaleSpine surgeryMale cohortPerception of healthFemale cohortAnalog scaleMean changeBaseline patient-reported outcome measuresVisual analog scale leg painEuroQol 5 dimensions questionnairePatient-reported outcome measuresPatient-reported outcome instrumentsBaseline patient demographicsLonger hospital stayOswestry Disability IndexSingle institutional studyOverall patient satisfactionLong-term patientsPatient-reported outcomesPatient satisfaction measuresPaucity of dataSpine OutcomesDisability Index