2023
Association Between Intravenous to Oral Opioid Transition Time and Length of Hospital Stay After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.
Hengartner A, Havlik J, David W, Reeves B, Freedman I, Sarkozy M, Maloy G, Fernandez T, Craft S, Koo A, Tuason D, DiLuna M, Elsamadicy A. Association Between Intravenous to Oral Opioid Transition Time and Length of Hospital Stay After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. The International Journal Of Spine Surgery 2023, 17: 468-476. PMID: 37076256, PMCID: PMC10312154, DOI: 10.14444/8448.Peer-Reviewed Original ResearchPosterior spinal fusionAdolescent idiopathic scoliosisExtended LOSSpinal fusionIdiopathic scoliosisMultivariate analysisMultilevel posterior spinal fusionLength of hospitalPostoperative complication rateMajor academic institutionOral opioidsHospital LOSStudy patientsDischarge dispositionHospital lengthPostoperative complicationsPostoperative courseComplication rateIntraoperative variablesLonger LOSPatient demographicsReadmission ratesMedical recordsUnivariate analysisOdds ratioMultiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts
Kundishora A, Allington G, McGee S, Mekbib K, Gainullin V, Timberlake A, Nelson-Williams C, Kiziltug E, Smith H, Ocken J, Shohfi J, Allocco A, Duy P, Elsamadicy A, Dong W, Zhao S, Wang Y, Qureshi H, DiLuna M, Mane S, Tikhonova I, Fu P, Castaldi C, López-Giráldez F, Knight J, Furey C, Carter B, Haider S, Moreno-De-Luca A, Alper S, Gunel M, Millan F, Lifton R, Torene R, Jin S, Kahle K. Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts. Nature Medicine 2023, 29: 667-678. PMID: 36879130, DOI: 10.1038/s41591-023-02238-2.Peer-Reviewed Original ResearchConceptsArachnoid cystCerebral arachnoid cystsDe novo variantsAC pathogenesisDevelopmental brain lesionsStructural brain diseaseAppropriate clinical contextPatients' medical recordsDamaging de novo variantsMedical recordsClinical severityBrain lesionsHealthy individualsAC subtypesBrain diseasesGenetic testingNeurodevelopmental pathologyClinical contextPathogenesisPatient phenotypesNeurodevelopmental programsNovo variantsRNA sequencing transcriptomeHuman brainCysts
2018
Socioeconomic Factors, Perioperative Complications, and 30-Day Readmission Rates Associated With Delayed Cranial Vault Reconstruction for Craniosynostosis
Sergesketter AR, Elsamadicy AA, Lubkin DT, Kemeny H, Harward SC, Krucoff KB, Krucoff MO, Fuchs H, Thompson EM, Allori AC, Marcus JR, Muh CR. Socioeconomic Factors, Perioperative Complications, and 30-Day Readmission Rates Associated With Delayed Cranial Vault Reconstruction for Craniosynostosis. Journal Of Craniofacial Surgery 2018, 29: 1767-1771. PMID: 30059426, DOI: 10.1097/scs.0000000000004787.Peer-Reviewed Original ResearchMeSH KeywordsChild, PreschoolCraniosynostosesDevelopmental DisabilitiesFemaleHealthcare DisparitiesHumansIncidenceInfantIntracranial HypertensionLanguageMalePatient ReadmissionPlastic Surgery ProceduresPostoperative ComplicationsRacial GroupsRetrospective StudiesRisk FactorsSkullSocioeconomic FactorsTime-to-TreatmentConceptsCranial vault reconstructionNon-English primary languageReadmission ratesMonths of ageMedicaid insurancePrimary cranial vault reconstructionCraniosynostosis patientsPerioperative complication ratePerioperative complicationsPrimary surgeryPatient demographicsComplication ratePatient barriersMedical recordsFirst consultIntracranial pressureSurgeryPatientsEsthetic consequencesPrimary languagePremature fusionDevelopmental disabilitiesSocioeconomic factorsComplicationsChildrenInfluence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery.
Elsamadicy AA, Kemeny H, Adogwa O, Sankey EW, Goodwin CR, Yarbrough CK, Lad SP, Karikari IO, Gottfried ON. Influence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery. Journal Of Neurosurgery Spine 2018, 29: 40-45. PMID: 29701564, DOI: 10.3171/2017.12.spine171079.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanDiagnostic Self EvaluationDisability EvaluationElective Surgical ProceduresFemaleHealth StatusHealthcare DisparitiesHumansLumbar VertebraeMaleMiddle AgedPainPatient Reported Outcome MeasuresPatient SatisfactionPrevalenceProspective StudiesRetrospective StudiesSelf ConceptTime FactorsWhite PeopleConceptsElective lumbar spine surgeryPatient-reported outcomesLumbar spine surgerySpine surgeryPatient satisfactionRacial disparitiesPatient demographicsReadmission ratesWhite patientsAA patientsMedical recordsLong-term patient-reported outcomesOverall patient-reported outcomeGreater body mass indexBaseline patient demographicsInferior surgical outcomesVAS-LP scoresPatient-reported satisfactionOverall patient satisfactionBody mass indexVisual analog scaleAfrican American patientsPatient-specific factorsPatient satisfaction measuresPerception of healthPreoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity
Elsamadicy AA, Adogwa O, Ongele M, Sergesketter AR, Tarnasky A, Lubkin DET, Drysdale N, Cheng J, Bagley CA, Karikari IO. Preoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity. World Neurosurgery 2018, 112: e348-e354. PMID: 29355811, DOI: 10.1016/j.wneu.2018.01.046.Peer-Reviewed Original ResearchConceptsElderly male patientsPreoperative Hgb levelsElective spinal fusionHealth care useHgb levelsSpinal fusionMale patientsPostoperative deliriumHemoglobin levelsCare useMean Hgb levelsNon-wound infectionsPreoperative hemoglobin levelLower hemoglobin levelsLower Hgb levelsQuality of careMajor academic institutionPreoperative HgbHospital stayPreoperative levelsPrimary outcomePreoperative identificationHematoma formationMedical recordsSpine surgery
2017
Effect of Social Support and Marital Status on Perceived Surgical Effectiveness and 30-Day Hospital Readmission
Adogwa O, Elsamadicy AA, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Effect of Social Support and Marital Status on Perceived Surgical Effectiveness and 30-Day Hospital Readmission. Global Spine Journal 2017, 7: 774-779. PMID: 29238642, PMCID: PMC5721993, DOI: 10.1177/2192568217696696.Peer-Reviewed Original ResearchElective spine surgerySpine surgeryHospital stayReadmission ratesOutcome measuresLong-term clinical outcomesThirty-day readmission ratesLength of hospitalPostoperative complication rateRetrospective cohort reviewTime of surgeryMarital statusSocial supportMajor academic medical centerAcademic medical centerSignificant differencesBaseline characteristicsCohort reviewPatient demographicsComplication rateHospital readmissionClinical outcomesSurgical outcomesSurgical effectivenessMedical recordsIncreased 30-Day Complication Rates Associated with Laminectomy in 874 Adult Patients with Spinal Deformity Undergoing Elective Spinal Fusion: A Single Institutional Study
Elsamadicy AA, Adogwa O, Warwick H, Sergesketter A, Lydon E, Shammas RL, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Increased 30-Day Complication Rates Associated with Laminectomy in 874 Adult Patients with Spinal Deformity Undergoing Elective Spinal Fusion: A Single Institutional Study. World Neurosurgery 2017, 102: 370-375. PMID: 28359921, DOI: 10.1016/j.wneu.2017.03.096.Peer-Reviewed Original ResearchConceptsElective spinal fusionSpinal fusionSpinal deformityAdult patientsComplication rateComplication Rates AssociatedAllogeneic blood transfusionPostoperative complication rateSingle institutional studyUrinary tract infectionHigh complication rateIntensive care unitMajor academic institutionPatient demographicsReadmission ratesTract infectionsBlood lossBlood transfusionPrimary outcomeWound drainageCare unitIntraoperative durotomyMedical recordsMental statusInstrumentation failureEffect of employment status on length of hospital stay, 30-day readmission and patient reported outcomes after spine surgery
Adogwa O, Elsamadicy AA, Fialkoff J, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Effect of employment status on length of hospital stay, 30-day readmission and patient reported outcomes after spine surgery. Journal Of Spine Surgery 2017, 3: 44-49. PMID: 28435917, PMCID: PMC5386895, DOI: 10.21037/jss.2017.03.08.Peer-Reviewed Original ResearchElective spine surgeryHospital staySpine surgeryReadmission ratesComplication ratePatient cohortFunctional improvementPeri-operative complication ratesPost-operative complication rateEmployment statusUnplanned hospital readmissionDays of dischargeGreater functional improvementMajor academic medical centerAcademic medical centerCause readmissionBaseline characteristicsPatient demographicsBlood lossHospital readmissionPrimary outcomeReadmission preventionUnemployed patientsOperative timeMedical recordsImpact of surgical approach on complication rates after elective spinal fusion (≥3 levels) for adult spine deformity
Elsamadicy AA, Adogwa O, Behrens S, Sergesketter A, Chen A, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Impact of surgical approach on complication rates after elective spinal fusion (≥3 levels) for adult spine deformity. Journal Of Spine Surgery 2017, 3: 31-37. PMID: 28435915, PMCID: PMC5386906, DOI: 10.21037/jss.2017.03.09.Peer-Reviewed Original ResearchElective spinal fusionAnterior/posterior approachAdult spine deformityPosterior approachSurgical approachSpinal fusionComplication ratePatient demographicsSpine deformityPost-operative complication rateAdult spine deformity patientsPost-operative complicationsHigher operative timeDifferent surgical approachesSpine deformity patientsMajor academic institutionRate of intraHigher EBLBlood transfusionPrimary outcomeIntraoperative durotomyOperative timeDeformity patientsMedical recordsHigh incidenceRisk Factors and Independent Predictors of 30-Day Readmission for Altered Mental Status After Elective Spine Surgery for Spine Deformity: A Single-Institutional Study of 1090 Patients
Elsamadicy AA, Adogwa O, Reddy GB, Sergesketter A, Warwick H, Jones T, Cheng J, Bagley CA, Karikari IO. Risk Factors and Independent Predictors of 30-Day Readmission for Altered Mental Status After Elective Spine Surgery for Spine Deformity: A Single-Institutional Study of 1090 Patients. World Neurosurgery 2017, 101: 270-274. PMID: 28192260, DOI: 10.1016/j.wneu.2017.02.001.Peer-Reviewed Original ResearchConceptsElective spine surgeryPostoperative complication rateIndependent predictorsSpine surgeryComplication rateSpine deformityRisk factorsAMS cohortPatient demographicsMental statusInferior surgical outcomesAltered mental statusMultivariate stepwise regression analysisIntensive care unitMajor academic institutionICU transferAdult patientsIntraoperative variablesPulmonary embolismPrimary outcomeCare unitSurgical outcomesMedical recordsReadmissionPatientsImpact of Obesity on Complications and 30-Day Readmission Rates After Cranial Surgery: A Single-Institutional Study of 224 Consecutive Craniotomy/Craniectomy Procedures
Sergesketter A, Elsamadicy AA, Gottfried ON. Impact of Obesity on Complications and 30-Day Readmission Rates After Cranial Surgery: A Single-Institutional Study of 224 Consecutive Craniotomy/Craniectomy Procedures. World Neurosurgery 2017, 100: 244-249. PMID: 28093346, DOI: 10.1016/j.wneu.2017.01.019.Peer-Reviewed Original ResearchConceptsImpact of obesityBody mass indexReadmission ratesCranial surgeryPostoperative complicationsMass indexSurgical outcomesPreoperative body mass indexMean body mass indexBaseline patient characteristicsEffect of obesityPrevalence of obesityMajor academic institutionHospital stayMost patientsObese cohortObese patientsPatient characteristicsSurgical complicationsBlood lossConsecutive patientsNonobese cohortPrimary outcomeTumor excisionMedical records
2016
Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Hobbs C, Behrens S, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients. World Neurosurgery 2016, 99: 418-423. PMID: 28003170, DOI: 10.1016/j.wneu.2016.12.029.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanElective Surgical ProceduresEquipment FailureEthnicityFemaleHumansIntensive Care UnitsIntraoperative ComplicationsLength of StayMaleMiddle AgedOperative TimePain, PostoperativePatient ReadmissionPostoperative ComplicationsRetrospective StudiesSpinal DiseasesSpinal FusionSurgical Wound DehiscenceUrinary Tract InfectionsWhite PeopleConceptsComplex spinal fusionPostoperative complicationsComplication rateSpinal fusionPatient demographicsReadmission ratesSimilar postoperative complicationsSingle institutional studyUrinary tract infectionSpinal fusion outcomesBody mass indexComplex spinal surgeryMajor academic institutionHospital stayTract infectionsAdult patientsPrimary outcomeWhite patientsBlack patientsOperative timeMass indexSurgical outcomesMedical recordsPatient raceSpinal surgeryAssociation Between Baseline Affective Disorders and 30-Day Readmission Rates in Patients Undergoing Elective Spine Surgery
Adogwa O, Elsamadicy AA, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Association Between Baseline Affective Disorders and 30-Day Readmission Rates in Patients Undergoing Elective Spine Surgery. World Neurosurgery 2016, 94: 432-436. PMID: 27450978, DOI: 10.1016/j.wneu.2016.07.045.Peer-Reviewed Original ResearchConceptsElective spine surgeryDays of dischargeSpine surgeryReadmission ratesPsychiatric comorbidityAffective disordersCause readmissionMultivariate logistic regression modelPatient-reported outcome measuresPatient-reported outcome dataRate of readmissionBody mass indexMajor academic medical centerAcademic medical centerLogistic regression modelsUnplanned readmissionBaseline characteristicsEarly readmissionPatient ageIndependent predictorsPrimary outcomeMass indexPsychologic disordersMedical recordsUnivariate analysis