2024
Implications of surgical infection on surgical and hospital outcomes after spine surgery: A NSQIP study of 410,930 patients
Elsamadicy A, Serrato P, Sadeghzadeh S, Dietz N, Lo S, Sciubba D. Implications of surgical infection on surgical and hospital outcomes after spine surgery: A NSQIP study of 410,930 patients. Clinical Neurology And Neurosurgery 2024, 245: 108505. PMID: 39173491, DOI: 10.1016/j.clineuro.2024.108505.Peer-Reviewed Original ResearchExtended hospital length of stayNon-routine dischargeLength of staySurgical infectionsHospital length of stayExtended hospital lengthRetrospective cohort studySpine surgeryAdverse eventsStudy Design Retrospective cohort studyCohort studyPredictors of adverse eventsMultivariate logistic regression analysisRate of adverse eventsProlonged length of stayACS NSQIP databaseRisk of complicationsPostoperative adverse eventsHealthcare resource utilizationICD-9/10 codesLogistic regression analysisNon-home dischargeNSQIP studiesDesign Retrospective cohort studyMean BMIRegional variations in morbidity and mortality among neonates with intraventricular hemorrhage: a national database analysis
Sayeed S, Theriault B, Hengartner A, Serrato P, Sadeghzadeh S, Belkasim S, Ahsan N, Elsamadicy E, DiLuna M, Elsamadicy A. Regional variations in morbidity and mortality among neonates with intraventricular hemorrhage: a national database analysis. Child's Nervous System 2024, 40: 1-10. PMID: 38955900, DOI: 10.1007/s00381-024-06514-5.Peer-Reviewed Original ResearchNational Inpatient SampleIntraoperative variablesLong-term neurodevelopmental outcomesLow gestational ageMultivariate logistic regression analysisPermanent CSF shuntNational database analysisLow birth weightPercentage of patientsRetrospective cohort studyAssociated with decreased oddsImpact of insurance statusAssociated with reduced oddsMedian total costAssociated with mortalityLogistic regression analysisBackgroundIntraventricular hemorrhageNeonatal IVHGestational ageIntraventricular hemorrhageNeurodevelopmental outcomesCSF diversionCSF shuntingCost of admissionBirth weightInsurance Disparities in Patient Outcomes and Healthcare Resource Utilization Following Neonatal Intraventricular Hemorrhage
Sayeed S, Theriault B, Hengartner A, Ahsan N, Sadeghzadeh S, Elsamadicy E, DiLuna M, Elsamadicy A. Insurance Disparities in Patient Outcomes and Healthcare Resource Utilization Following Neonatal Intraventricular Hemorrhage. World Neurosurgery 2024, 189: e46-e54. PMID: 38815926, DOI: 10.1016/j.wneu.2024.05.136.Peer-Reviewed Original ResearchIntraventricular hemorrhagePI patientsInsurance statusAssociated with surgical delayDiagnosis of intraventricular hemorrhageMultivariate logistic regression analysisNeonatal intraventricular hemorrhageAssociated with increased healthcare utilizationNational Inpatient Sample databaseRetrospective cohort studyImpact of insurance statusTime to referralAssociated with increased oddsInpatient Sample databaseAssociation of insurance statusLogistic regression analysisLength of stayMyelomeningocele repairSurgical delayCost of admissionAdverse eventsPrivate insuranceCohort studyMedicaid patientsPI cohortSociodemographic Disparities and Postoperative Outcomes Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database
Hengartner A, Serrato P, Sayeed S, Sadeghzadeh S, Prassinos A, Alperovich M, DiLuna M, Elsamadicy A. Sociodemographic Disparities and Postoperative Outcomes Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database. Journal Of Craniofacial Surgery 2024, 35: 1310-1314. PMID: 38752737, DOI: 10.1097/scs.0000000000010303.Peer-Reviewed Original ResearchNon-Hispanic blacksNon-Hispanic whitesLength of stayCranial vault repairAdverse eventsNational Surgical Quality Improvement Program-Pediatric databaseAmerican College of Surgeons National Surgical Quality Improvement Program Pediatric databaseMultivariate logistic regression analysisNSQIP-Pediatric databaseAge of presentationNon-Hispanic Black patientsNon-Hispanic white patientsIncreased complication rateHospital length of stayExtended length of stayPostoperative clinical outcomesEquitable health careRetrospective cohort studyCranial vault remodelingCurrent Procedural Terminology codesPostoperative adverse eventsCranial vault reconstructionProcedural Terminology codesLogistic regression analysisNon-white patientsReduced racial disparities among newborns with intraventricular hemorrhage
Sayeed S, Reeves B, Theriault B, Hengartner A, Ahsan N, Sadeghzadeh S, Elsamadicy E, DiLuna M, Elsamadicy A. Reduced racial disparities among newborns with intraventricular hemorrhage. Child's Nervous System 2024, 40: 2051-2059. PMID: 38526575, DOI: 10.1007/s00381-024-06369-w.Peer-Reviewed Original ResearchLength of stayIntroductionIntraventricular hemorrhageAdverse eventsMultivariate logistic regression analysisRate of adverse eventsPermanent neurological dysfunctionProlonged length of stayNational Inpatient Sample databaseRates of NECInpatient Sample databaseLogistic regression analysisIntraventricular hemorrhageAA patientsImpact of raceCost of admissionIndependent predictorsRate of mortalityPatient characteristicsMultivariate analysisPercentage of AAWhite patientsNeurological dysfunctionNewbornsPatient genderPatients
2023
Influence of affective disorders on outcomes after suboccipital decompression for adult Chiari I malformation
Sherman J, Sayeed S, Craft S, Reeves B, Hengartner A, Fernandez T, Koo A, DiLuna M, Elsamadicy A. Influence of affective disorders on outcomes after suboccipital decompression for adult Chiari I malformation. Clinical Neurology And Neurosurgery 2023, 236: 108104. PMID: 38171050, DOI: 10.1016/j.clineuro.2023.108104.Peer-Reviewed Original ResearchHealthcare resource utilizationNon-routine dischargeLength of stayChiari I malformationAD cohortSuboccipital decompressionAffective disordersAdverse eventsPatient demographicsPostoperative eventsAdmission costsExtended LOSMean LOSNational Inpatient Sample databaseMultivariate logistic regression analysisAdult Chiari I malformationIncidence of syringomyeliaPerioperative adverse eventsChronic pulmonary diseaseICD-10-CM codesGreater proportionLogistic regression analysisComorbid affective disordersAdult patientsIndependent predictorsImpact of Preoperative Frailty on Outcomes in Patients with Cervical Spondylotic Myelopathy Undergoing Anterior vs. Posterior Cervical Surgery
Elsamadicy A, Sayeed S, Sherman J, Craft S, Reeves B, Lo S, Shin J, Sciubba D. Impact of Preoperative Frailty on Outcomes in Patients with Cervical Spondylotic Myelopathy Undergoing Anterior vs. Posterior Cervical Surgery. Journal Of Clinical Medicine 2023, 13: 114. PMID: 38202121, PMCID: PMC10779741, DOI: 10.3390/jcm13010114.Peer-Reviewed Original ResearchNon-routine dischargeHealthcare resource utilizationAdverse eventsHealth care utilizationFrail patientsIndependent predictorsPreoperative frailtySevere frailtyExtended LOSCare utilizationFrail cohortIncidence of AEsGreater health care utilizationMultivariate logistic regression analysisMore frail patientsPosterior cervical decompressionRetrospective cohort studyAnterior cervical discectomyPerioperative adverse eventsAdditional prospective studiesNational Inpatient SamplePosterior cervical surgeryLogistic regression analysisHigh rateCervical decompressionRacial/Ethnic Disparities Among Patients Undergoing Anterior Cervical Discectomy and Fusion or Posterior Cervical Decompression and Fusion for Cervical Spondylotic Myelopathy: A National Administrative Database Analysis
Elsamadicy A, Sayeed S, Sherman J, Craft S, Reeves B, Hengartner A, Koo A, Larry Lo S, Shin J, Mendel E, Sciubba D. Racial/Ethnic Disparities Among Patients Undergoing Anterior Cervical Discectomy and Fusion or Posterior Cervical Decompression and Fusion for Cervical Spondylotic Myelopathy: A National Administrative Database Analysis. World Neurosurgery 2023, 183: e372-e385. PMID: 38145651, DOI: 10.1016/j.wneu.2023.12.103.Peer-Reviewed Original ResearchCervical spondylotic myelopathyNon-routine dischargeHealthcare resource utilizationExtended hospital LOSHospital LOSWhite patientsHispanic patientsPatient raceNational Inpatient Sample databaseMultivariate logistic regression analysisGreater comorbidity burdenRacial/Ethnic DisparitiesAdministrative database analysisLogistic regression analysisRace/ethnicityACDF cohortComorbidity burdenPostoperative complicationsAdult patientsAdverse eventsPatient demographicsSpondylotic myelopathyIndependent predictorsSurgical outcomesBlack raceAssociated Risk Factors for Extended Operative Time Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database
Serrato P, Hengartner A, Sayeed S, Prassinos A, Alperovich M, DiLuna M, Elsamadicy A. Associated Risk Factors for Extended Operative Time Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database. Journal Of Craniofacial Surgery 2023, 35: 427-431. PMID: 38078913, DOI: 10.1097/scs.0000000000009920.Peer-Reviewed Original ResearchExtended operative timeCranial vault remodelingRetrospective cohort studyAdverse eventsCohort studyIndependent predictorsPediatric patientsOperative timeRisk factorsVault remodelingNational Surgical Quality Improvement Program-PediatricHealth care resource utilizationPostoperative surgical site infectionSurgeons National Surgical Quality Improvement Program-PediatricMultivariate logistic regression analysisDiseases 9/10 codesNSQIP-Pediatric databasePostoperative adverse eventsHigher American SocietySurgical site infectionAssociated risk factorsSurgical adverse eventsLength of stayLogistic regression analysisNon-Hispanic whitesAssociated Risk Factors for Extended Length of Stay Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database
Hengartner A, Serrato P, Sayeed S, Prassinos A, Alperovich M, DiLuna M, Elsamadicy A. Associated Risk Factors for Extended Length of Stay Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database. Journal Of Craniofacial Surgery 2023, 35: 384-387. PMID: 37943085, DOI: 10.1097/scs.0000000000009847.Peer-Reviewed Original ResearchCranial vault remodelingLOS cohortExtended LOSAdverse eventsPediatric patientsRisk factorsNational Surgical Quality Improvement Program Pediatric databaseVault remodelingSurgeons National Surgical Quality Improvement Program Pediatric databaseNon-Hispanic white patientsHealth care resource utilizationMultivariate logistic regression analysisDiseases 9/10 codesNSQIP-Pediatric databasePostoperative hospital LOSStructural pulmonary abnormalityPostoperative adverse eventsRetrospective cohort studyAssociated risk factorsMultivariate logistic regressionLogistic regression analysisCurrent Procedural TerminologyHospital LOSAnesthesiologists classificationPerioperative complicationsImplications of Frailty on Postoperative Health Care Resource Utilization in Ankylosing Spondylitis Patients Undergoing Spine Surgery for Spinal Fractures
Elsamadicy A, Sayeed S, Sadeghzadeh S, Reeves B, Sherman J, Craft S, Serrato P, Larry Lo S, Sciubba D. Implications of Frailty on Postoperative Health Care Resource Utilization in Ankylosing Spondylitis Patients Undergoing Spine Surgery for Spinal Fractures. World Neurosurgery 2023, 182: e16-e28. PMID: 37925147, DOI: 10.1016/j.wneu.2023.10.136.Peer-Reviewed Original ResearchNon-routine dischargeExtended hospital stayIndependent predictorsHospital stayAdverse eventsModified Frailty Index scoreNational Inpatient Sample databaseMultivariate logistic regression analysisFrailty index scoreHealthcare resource utilizationNumber of comorbiditiesHigher hospital costsPosterior spinal fusionCost of admissionImplications of frailtyLogistic regression analysisMultiple adverse eventsHealth care costsQuality patient careGreater comorbidityAdult patientsSpondylitis patientsElective surgeryRetrospective studySurgical outcomes
2022
Geriatric relationship with inpatient opioid consumption and hospital outcomes after open posterior spinal fusion for adult spine deformity
Elsamadicy A, Sandhu M, Reeves B, Sherman J, Craft S, Williams M, Shin J, Sciubba D. Geriatric relationship with inpatient opioid consumption and hospital outcomes after open posterior spinal fusion for adult spine deformity. Clinical Neurology And Neurosurgery 2022, 224: 107532. PMID: 36436433, DOI: 10.1016/j.clineuro.2022.107532.Peer-Reviewed Original ResearchConceptsNon-routine dischargeHealthcare resource utilizationAdverse eventsGeriatric cohortMME useGeriatric patientsSpinal fusionSpine deformityMultivariate logistic regression analysisInpatient narcotic consumptionInpatient opioid consumptionInpatient opioid usePremier Healthcare DatabasePoor surgical outcomesPatient risk stratificationPosterior spinal fusionAdult spinal deformityAdult spine deformityICD-10-CM codesGreater proportionLogistic regression analysisGreater resource utilizationNon-Hispanic whitesOlder CohortOpioid consumptionHospital Frailty Risk Score Predicts Adverse Events and Readmission Following a Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus
Koo AB, Elsamadicy AA, Renedo D, Sarkozy M, Reeves BC, Barrows MM, Hengartner A, Havlik J, Sandhu MRS, Antonios JP, Malhotra A, Matouk CC. Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following a Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus. World Neurosurgery 2022, 170: e9-e20. PMID: 35970293, DOI: 10.1016/j.wneu.2022.08.037.Peer-Reviewed Original ResearchConceptsHospital Frailty Risk ScoreFrailty Risk ScoreVP shunt surgeryVentriculoperitoneal shunt surgeryAdverse eventsShunt surgeryIndependent predictorsNPH patientsRisk scoreHealth care resource utilizationMultivariate logistic regression analysisNormal pressure hydrocephalus patientsRetrospective cohort studyNationwide Readmissions DatabaseNormal pressure hydrocephalusLogistic regression analysisRegression analysisMultivariate regression analysisUnplanned readmissionCohort studyHospital readmissionPressure hydrocephalusAdmission costsReadmissionHydrocephalus patientsAssessment of Frailty Indices and Charlson Comorbidity Index for Predicting Adverse Outcomes in Patients Undergoing Surgery for Spine Metastases: A National Database Analysis
Elsamadicy AA, Havlik JL, Reeves B, Sherman J, Koo AB, Pennington Z, Hersh AM, Sandhu MRS, Kolb L, Larry Lo SF, Shin JH, Mendel E, Sciubba DM. Assessment of Frailty Indices and Charlson Comorbidity Index for Predicting Adverse Outcomes in Patients Undergoing Surgery for Spine Metastases: A National Database Analysis. World Neurosurgery 2022, 164: e1058-e1070. PMID: 35644519, DOI: 10.1016/j.wneu.2022.05.101.Peer-Reviewed Original ResearchConceptsMetastatic spinal tumor frailty indexCharlson Comorbidity IndexFrailty indexMFI-5Adverse outcomesNonroutine dischargeComorbidity indexUnplanned readmissionAdverse eventsNational Surgical Quality Improvement Program databaseHigher Charlson comorbidity indexQuality Improvement Program databaseMultivariate logistic regression analysisPredicting Adverse OutcomesRetrospective cohort studyImprovement Program databaseNational database analysisLength of stayLogistic regression analysisExtradural spinal metastasisOnly significant predictorAdult patientsCohort studyProlonged lengthIndependent predictorsHigher Hospital Frailty Risk Score is associated with increased complications and healthcare resource utilization after endovascular treatment of ruptured intracranial aneurysms
Koo AB, Elsamadicy AA, Renedo D, Sarkozy M, Sherman J, Reeves BC, Havlik J, Antonios J, Sujijantarat N, Hebert R, Malhotra A, Matouk C. Higher Hospital Frailty Risk Score is associated with increased complications and healthcare resource utilization after endovascular treatment of ruptured intracranial aneurysms. Journal Of NeuroInterventional Surgery 2022, 15: 255-261. PMID: 35292571, PMCID: PMC8931798, DOI: 10.1136/neurintsurg-2021-018484.Peer-Reviewed Original ResearchConceptsHospital Frailty Risk ScoreNon-routine dischargeLength of stayFrailty Risk ScoreHealthcare resource utilizationTotal hospital costsEndovascular treatmentIntracranial aneurysmsAdverse eventsHospital costsRisk scoreHighest Hospital Frailty Risk ScoresMean LOSNational Inpatient Sample databaseMean total hospital costMultivariate logistic regression analysisImpact of frailtyRetrospective cohort studyICD-10-CM codesLogistic regression analysisRegression analysisMultivariate regression analysisCohort studyDischarge dispositionPatient demographicsImpact of Frailty on Morbidity and Mortality in Adult Patients Undergoing Surgical Evacuation of Acute Traumatic Subdural Hematoma
Elsamadicy AA, Sandhu MRS, Freedman IG, Koo AB, Reeves BC, Yu J, Hengartner A, Havlik J, Hong CS, Rutherford HJV, Kim JA, Gerrard J, Gilmore EJ, Omay SB. Impact of Frailty on Morbidity and Mortality in Adult Patients Undergoing Surgical Evacuation of Acute Traumatic Subdural Hematoma. World Neurosurgery 2022, 162: e251-e263. PMID: 35276399, DOI: 10.1016/j.wneu.2022.02.122.Peer-Reviewed Original ResearchConceptsAcute traumatic subdural hematomaTraumatic subdural hematomaHospital mortalityNonroutine dischargeSubdural hematomaExtended LOSIndependent predictorsAdult patientsBaseline frailtyMultivariate logistic regression analysisExtended hospital lengthImpact of frailtyRetrospective cohort studyNational Trauma DatabaseLogistic regression analysisRegression analysisMultivariate regression analysisHealth care expendituresFrail patientsHospital lengthCohort studySurgical evacuationFrailty indexTrauma databasePatients307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured Aneurysms
Koo A, Elsamadicy A, Sarkozy M, Sherman J, Reeves B, Freedman I, Antonios J, Sujijantarat N, Renado D, Hebert R, Malhotra A, Matouk C. 307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured Aneurysms. Neurosurgery 2022, 68: 67-68. DOI: 10.1227/neu.0000000000001880_307.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreNon-routine dischargeFrailty Risk ScoreEndovascular treatmentIntracranial aneurysmsPerioperative complicationsLower frailtyHospital costsRisk scoreNational Inpatient Sample databaseMean total hospital costMultivariate logistic regression analysisICD-10 diagnostic codesImpact of frailtyRetrospective cohort studyHealthcare resource utilizationEvaluation of patientsTotal hospital costsAdverse healthcare outcomesAdministrative hospital dataRuptured intracranial aneurysmLogistic regression analysisRegression analysisMultivariate regression analysisAdult patients464 Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Metastatic Spinal Column Tumors
Elsamadicy A, Koo A, Reeves B, Pennington Z, Yu J, Goodwin C, Kolb L, Laurans M, Lo S, Shin J, Sciubba D. 464 Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Metastatic Spinal Column Tumors. Neurosurgery 2022, 68: 113-113. DOI: 10.1227/neu.0000000000001880_464.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreNon-routine dischargeFrailty Risk ScoreSpinal column tumorsPatient populationRisk scoreLarge national database studyNational Inpatient Sample databaseMultivariate logistic regression analysisICD-10 diagnostic codesProlonged hospital LOSImpact of frailtyNational database studyHealthcare resource utilizationRetrospective cohort studyTotal hospital costsProcedural Coding SystemLogistic regression analysisRegression analysisMultivariate regression analysisHospital LOSCohort studyHospital admissionIndependent predictorsLonger LOSHospital Frailty Risk Score and healthcare resource utilization after surgery for metastatic spinal column tumors.
Elsamadicy AA, Koo AB, Reeves BC, Pennington Z, Yu J, Goodwin CR, Kolb L, Laurans M, Lo SL, Shin JH, Sciubba DM. Hospital Frailty Risk Score and healthcare resource utilization after surgery for metastatic spinal column tumors. Journal Of Neurosurgery Spine 2022, 37: 241-251. PMID: 35148505, DOI: 10.3171/2022.1.spine21987.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreLength of staySpinal column tumorsFrailty Risk ScoreNonroutine dischargeHospital admissionHigh frailtyIntermediate frailtyDischarge dispositionSpinal tumorsLower frailtyDiagnostic codesRisk scoreHigher total hospital costsMean LOSNational Inpatient Sample databaseMultivariate logistic regression analysisICD-10 diagnostic codesImpact of frailtyRetrospective cohort studyHealthcare resource utilizationProportion of patientsTotal hospital costsProcedural Coding SystemLogistic regression analysisDifferences in Health Care Resource Utilization After Surgery for Metastatic Spinal Column Tumors in Patients with a Concurrent Affective Disorder in the United States
Elsamadicy AA, Koo AB, Sarkozy M, Reeves BC, Pennington Z, Havlik J, Sandhu MR, Hersh A, Patel S, Kolb L, Larry Lo SF, Shin JH, Mendel E, Sciubba DM. Differences in Health Care Resource Utilization After Surgery for Metastatic Spinal Column Tumors in Patients with a Concurrent Affective Disorder in the United States. World Neurosurgery 2022, 161: e252-e267. PMID: 35123021, DOI: 10.1016/j.wneu.2022.01.112.Peer-Reviewed Original ResearchConceptsLength of stayHealth care resource utilizationPostoperative adverse eventsNonroutine dischargeAdverse eventsAffective disordersNational Inpatient Sample databaseMultivariate logistic regression analysisSpinal column metastasesRetrospective cohort studyMetastatic spinal tumorsSpinal column tumorsLogistic regression analysisConcurrent affective disorderGreater total costsRegression analysisMultivariate regression analysisAdult patientsCohort studyDischarge dispositionIntraoperative variablesPatient demographicsHospital admissionIndependent predictorsSpinal metastases