Antiseizure Medication Use and Outcomes After Suspected or Confirmed Acute Symptomatic Seizures
Zafar S, Sivaraju A, Rubinos C, Ayub N, Awodutire P, McKee Z, Chandan P, Byrnes M, Bhansali S, Rice H, Smith-Ayala A, Haider M, Tveter E, Erlich-Malona N, Ibanhes F, DeMarco A, Lewis S, Dhakar M, Punia V. Antiseizure Medication Use and Outcomes After Suspected or Confirmed Acute Symptomatic Seizures. JAMA Neurology 2024, 81: 1159-1169. PMID: 39312247, PMCID: PMC11420826, DOI: 10.1001/jamaneurol.2024.3189.Peer-Reviewed Original ResearchAssociated with increased oddsAcute symptomatic seizuresAntiseizure medication treatmentDischarge prescriptionsSymptomatic seizuresAntiseizure medicationsElectrographic seizuresContinuous electroencephalographyOdds of treatmentGlasgow Outcome Scale scoreNeurological intensive care unitOptimal treatment durationMulticenter cohort studyAntiseizure medication useOutcome Scale scorePrescribed antiseizure medicationsAssociated with functional outcomeIntensive care unitAssociated with outcomeMain OutcomesProgressive brain injuryASM treatmentMedication useCohort studyEpileptiform abnormalitiesPredictors of follow-up care for critically-ill patients with seizures and epileptiform abnormalities on EEG monitoring
Rice H, Fernandes M, Punia V, Rubinos C, Sivaraju A, Zafar S. Predictors of follow-up care for critically-ill patients with seizures and epileptiform abnormalities on EEG monitoring. Clinical Neurology And Neurosurgery 2024, 241: 108275. PMID: 38640778, PMCID: PMC11167629, DOI: 10.1016/j.clineuro.2024.108275.Peer-Reviewed Original ResearchConceptsNeurological follow-upFollow-up visitFollow-upAntiseizure medicationsOutpatient follow-upCritically-ill patientsContinuous EEGEpileptiform abnormalitiesPredictors of follow-upPrevent long-term complicationsIllness severityYounger ageRetrospective cohort studyLong-term complicationsFollow-up statusIntensive care unitProbability of follow-upHigher illness severityPredictors of readmissionContinuous EEG recordingsRisk stratificationEEG monitoringCohort studyCritically-illCare unit