1996
Function and expression of a human idiotypic network in Schistosomiasis japonica
WISNEWSKI A, OLDS G, JOHNSON J, RAMIREZ B, KRESINA T. Function and expression of a human idiotypic network in Schistosomiasis japonica. Parasite Immunology 1996, 18: 439-447. PMID: 9226679, DOI: 10.1111/j.1365-3024.1996.tb01027.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsAntibodies, Anti-IdiotypicAntibodies, HelminthAntibodies, HeterophileAntigens, HelminthChildFemaleGranulomaHumansImmunoglobulin GImmunoglobulin IdiotypesIn Vitro TechniquesLymphocyte ActivationMiceOvumPregnancySchistosoma japonicumSchistosomiasis japonicaSolubilityT-LymphocytesConceptsS. japonicum soluble egg antigensAnti-idiotypic antibodiesSchistosomiasis japonicaHuman anti-idiotypic antibodySoluble egg antigenNon-related antigensAnti-idiotypic antiseraS. japonicum infectionHuman lymphocyte blastogenesisCross-reactive idiotypeDose-dependent mannerHepatosplenic diseaseAcute infectionSerum levelsBlastogenic responseLymphocyte blastogenesisEgg antigenImmunoregulatory networkGranuloma formationJaponicum infectionFormation assaysS. japonicumAntibodiesAntigenDependent manner
1995
Induction of protective immunity to schistosomiasis with immunologically cross-reactive Lumbricus molecules
Wisnewski AV, Kresina TF. Induction of protective immunity to schistosomiasis with immunologically cross-reactive Lumbricus molecules. International Journal For Parasitology 1995, 25: 503-510. PMID: 7543459, DOI: 10.1016/0020-7519(94)00132-8.Peer-Reviewed Original ResearchConceptsVaccination of miceCandidate vaccine moleculesS. japonicum infectionS. japonicum paramyosinSchistosomiasis patients' seraMurine immune seraSchistosomiasis patientsProtective immunitySchistosome infectionPatient seraJaponicum infectionImmune serumUninfected individualsAntibody productionAntigen preparationsVaccine moleculesMultiple antigensRodent seraParasite moleculesMurine antibodyCross-reactive moleculesS. japonicumSerumAntigenSchistosoma japonicum
1994
Human monoclonal antibodies heterogeneously express a human cross-reactive idiotype associated with immune function in Schistosoma japonicum infection.
Wisnewski AV, Olds GR, Kresina TF. Human monoclonal antibodies heterogeneously express a human cross-reactive idiotype associated with immune function in Schistosoma japonicum infection. Human Antibodies 1994, 5: 178-82. PMID: 7756581.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalCross ReactionsHumansHybrid CellsLymphocyte ActivationMiceSchistosoma japonicumSchistosomiasisConceptsHuman monoclonal antibodyEpstein-Barr virusSchistosoma japonicum infectionCross-reactive idiotypeJaponicum infectionImmune functionMonoclonal antibodiesSoluble egg antigenS. japonicum infectionWestern blot profilesSchistosomiasis patientsBarr virusEgg antigenHuman idiotypeIdiotype expressionReactive idiotypeMultiple antigensSerological analysisS. japonicumIdiotypeInfectionAntigenHeterogeneous expressionLevel of suppressionPatients
1991
An immunoregulatory human monoclonal antibody in schistosomiasis japonica
Kresina T, Guan X, Posner M, Wisnewski A, Olds G. An immunoregulatory human monoclonal antibody in schistosomiasis japonica. Human Antibodies 1991, 2: 42-45. PMID: 1651785, DOI: 10.3233/hab-1991-2107.Peer-Reviewed Original ResearchConceptsHuman monoclonal antibodyMonoclonal antibodiesEgg antigenAntigen-induced blastogenesisAdult wormsEpstein-Barr virusSoluble egg antigenOS cell linesWestern blot analysisChronic schistosomiasisSoluble eggBarr virusChinese patientsChronic diseasesAntibody-producing hybridomasAntigen reactivitySchistosomiasis japonicaCarbohydrate antigensWestern blotDecompression operationMurine splenocytesSplenocytesAntibodiesAntigenSchistosoma japonicum