2023
A Measure of Neural Function Provides Unique Insights into Behavioral Deficits in Acute Stroke
Vanderschelden B, Erani F, Wu J, de Havenon A, Srinivasan R, Cramer S. A Measure of Neural Function Provides Unique Insights into Behavioral Deficits in Acute Stroke. Stroke 2023, 54: e25-e29. PMID: 36689596, PMCID: PMC9881885, DOI: 10.1161/strokeaha.122.040841.Peer-Reviewed Original ResearchConceptsInitial NIHSS scoreNIHSS scoreAcute strokeNeural functionBehavioral deficitsHealth Stroke Scale scoreBivariate analysisInitial National InstitutesStroke Scale scoreEmergency department settingMultivariable linear regressionInfarct volumeEEG measuresStroke deficitsDiabetes statusEmergency departmentEEG findingsSelection operator (LASSO) regressionUniversity HospitalDepartment settingSpectral powerScale scoreClinical modelStrokeMultivariate modelTrends in Venous Thromboembolism Readmission Rates after Ischemic Stroke and Intracerebral Hemorrhage
Shu L, de Havenon A, Liberman A, Henninger N, Goldstein E, Reznik M, Mahta A, Al-Mufti F, Frontera J, Furie K, Yaghi S. Trends in Venous Thromboembolism Readmission Rates after Ischemic Stroke and Intracerebral Hemorrhage. Journal Of Stroke 2023, 25: 151-159. PMID: 36592970, PMCID: PMC9911841, DOI: 10.5853/jos.2022.02215.Peer-Reviewed Original ResearchLonger hospital stayVenous thromboembolismIntracerebral hemorrhageVTE readmissionHospital stayReadmission ratesUtilization Project Nationwide Readmissions DatabaseAcute ischemic stroke hospitalizationsHealth Stroke Scale scoreHistory of VTEVTE risk scoreStroke Scale scoreHigher National InstitutesHigh-risk patientsLife-threatening complicationsNationwide Readmissions DatabasePrincipal discharge diagnosisCox regression modelIschemic stroke hospitalizationsIndex admissionVTE diagnosisVTE prophylaxisVTE ratesVTE riskIschemic stroke
2021
Investigating the “Weekend Effect” on Outcomes of Patients Undergoing Endovascular Mechanical Thrombectomy for Ischemic Stroke
Grandhi R, Ravindra VM, Ney JP, Zaidat O, Taussky P, de Havenon A. Investigating the “Weekend Effect” on Outcomes of Patients Undergoing Endovascular Mechanical Thrombectomy for Ischemic Stroke. Journal Of Stroke And Cerebrovascular Diseases 2021, 30: 106013. PMID: 34375859, PMCID: PMC8511062, DOI: 10.1016/j.jstrokecerebrovasdis.2021.106013.Peer-Reviewed Original ResearchMeSH KeywordsAfter-Hours CareAgedAged, 80 and overCross-Sectional StudiesDatabases, FactualEndovascular ProceduresFemaleHospital CostsHospital MortalityHumansInpatientsIschemic StrokeLength of StayMaleMiddle AgedPatient DischargeRetrospective StudiesRisk AssessmentRisk FactorsThrombectomyTime FactorsTreatment OutcomeUnited StatesConceptsAcute ischemic strokeEndovascular thrombectomyIschemic strokeLarge vessel occlusion ischemic strokeHealth Stroke Scale scoreNationwide Inpatient Sample dataStroke Scale scoreExtended hospital stayWorse clinical outcomesCross-sectional analysisLogistic regression modelsHospital deathHospital staySecondary outcomesPrimary outcomeClinical outcomesAIS patientsNormal working hoursPatientsScale scoreFavorable dischargeExposure variablesStrokeWeekends/National Institute
2020
Benefit of endovascular thrombectomy for M2 middle cerebral artery occlusion in the ARISE II study
de Havenon A, Narata AP, Amelot A, Saver JL, Bozorgchami H, Mattle HP, Ribo M, Andersson T, Zaidat OO, investigators A. Benefit of endovascular thrombectomy for M2 middle cerebral artery occlusion in the ARISE II study. Journal Of NeuroInterventional Surgery 2020, 13: 779-783. PMID: 33219148, PMCID: PMC8134506, DOI: 10.1136/neurintsurg-2020-016427.Peer-Reviewed Original ResearchConceptsMiddle cerebral artery occlusionM2 occlusionsCerebral artery occlusionM1 occlusionEndovascular thrombectomyAdverse eventsBetter outcomesArtery occlusionIschemic strokeReperfusion ratesM2-segment middle cerebral artery occlusionM2 middle cerebral artery occlusionsScale scoreHealth Stroke Scale scoreBaseline National InstitutesStroke Scale scoreAcute ischemic strokeMajor adverse eventsRankin Scale scorePaucity of dataLogistic regression modelsII trialSuccessful reperfusionII studyPrespecified analysisPrediction of death after endovascular thrombectomy in the extended window: a secondary analysis of DEFUSE 3 "
Taussky P, Agnoletto G, Grandhi R, Alexander MD, Wong KH, Albers GW, de Havenon A. Prediction of death after endovascular thrombectomy in the extended window: a secondary analysis of DEFUSE 3 ". Journal Of NeuroInterventional Surgery 2020, 13: 805-808. PMID: 33077580, PMCID: PMC8093992, DOI: 10.1136/neurintsurg-2020-016548.Peer-Reviewed Original ResearchConceptsEndovascular thrombectomyDEFUSE 3Statin usePrimary outcomeInclusion criteriaPredictive scoreHealth Stroke Scale scoreDEFUSE 3 studyEVT-treated patientsSecondary cohort analysisBaseline National InstitutesStroke Scale scoreHistory of diabetesPrediction of deathSelective inclusion criteriaUnivariate regression analysisHigh-risk categoryPotential predictive variablesEVT patientsPatient ageEndovascular therapyImaging evaluationPreprocedural variablesClinical trialsLethal outcome
2017
Association of Collateral Blood Vessels Detected by Arterial Spin Labeling Magnetic Resonance Imaging With Neurological Outcome After Ischemic Stroke
de Havenon A, Haynor DR, Tirschwell DL, Majersik JJ, Smith G, Cohen W, Andre JB. Association of Collateral Blood Vessels Detected by Arterial Spin Labeling Magnetic Resonance Imaging With Neurological Outcome After Ischemic Stroke. JAMA Neurology 2017, 74: 453-458. PMID: 28192548, PMCID: PMC5470363, DOI: 10.1001/jamaneurol.2016.4491.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeArterial spin labeling magnetic resonance imagingCollateral blood vesselsNeurologic outcomeMRS scoreMagnetic resonance imagingNeurological outcomeIschemic strokeScale scoreHealth Stroke Scale scoreResonance imagingMultivariable ordinal logistic regression modelsTertiary academic medical centerBlood vesselsAdmission National InstitutesPremorbid mRS scoreGood neurologic outcomeGood neurological outcomeRetrospective cohort studyStroke Scale scoreRankin Scale scorePresence of collateralsAcademic medical centerLogistic regression modelsOrdinal logistic regression models