2021
Penumbra Consumption Rates Based on Time-to-Maximum Delay and Reperfusion Status: A Post Hoc Analysis of the DEFUSE 3 Trial
Yaghi S, Raz E, Dehkharghani S, Riina H, McTaggart R, Jayaraman M, Prabhakaran S, Liebeskind DS, Khatri P, Mac Grory B, Al-Mufti F, Lansberg M, Albers G, de Havenon A. Penumbra Consumption Rates Based on Time-to-Maximum Delay and Reperfusion Status: A Post Hoc Analysis of the DEFUSE 3 Trial. Stroke 2021, 52: 2690-2693. PMID: 34157865, DOI: 10.1161/strokeaha.120.033806.Peer-Reviewed Original ResearchConceptsDEFUSE-3 trialsLarge vessel occlusionPenumbral tissueVessel occlusionMismatch volumeAcute large vessel occlusionAnterior circulation occlusionEndovascular thrombectomy patientsAcute ischemic strokePost Hoc AnalysisReperfusion statusThrombectomy patientsTICI 0Cerebral infarctionEndovascular thrombectomyIschemic strokeUntreated patientsPrimary outcomeSalvageable tissueTreatment modalitiesHoc AnalysisPerfusion timePatientsNatural historyOcclusion
2017
Advanced imaging in acute ischemic stroke.
Kilburg C, Scott McNally J, de Havenon A, Taussky P, Kalani MY, Park MS. Advanced imaging in acute ischemic stroke. Neurosurgical FOCUS 2017, 42: e10. PMID: 28366054, DOI: 10.3171/2017.1.focus16503.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeLarge vessel occlusionTranscranial Doppler ultrasonographyCT angiographyVessel wall MRIMR angiographyIschemic strokeDoppler ultrasonographyVessel occlusionMRI techniquesCollateral blood flowImaging modalitiesConventional CTCharacteristics of lesionsFour-dimensional CT angiographyClot burdenCryptogenic strokeAcute settingStroke treatmentPatent foramenOccult lesionsInvasive alternativeBlood flowNew imaging modalityNatural history