Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsVanessa Scanlon, PhD
Assistant Professor AdjunctAbout
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Titles
Assistant Professor Adjunct
Biography
Vanessa Scanlon is an Assistant Professor at the University of Connecticut. She is passionate about science and strengthening the pipeline of underrepresented individuals to successful research careers. Her research interests include hematopoiesis and the bone marrow microenvironment. In her spare time, she enjoys live music, gardening and star gazing.
Appointments
Laboratory Medicine
Assistant Professor AdjunctPrimary
Other Departments & Organizations
Education & Training
- PhD
- UConn Health, Biomedical Science (2015)
- BS
- UConn, MCB (2006)
- BS
- UConn, DGS (2006)
Research
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Overview
Currently, I work on understanding extrinsic mechanisms that underly hematopoietic progenitor cell fate decisions. I have developed a novel method for time-lapse microscopy of bipotent progenitors dividing and committing to two potential lineages. I'm also interested in developing 3D engineered in vitro cell culture models to further investigate spatial regulation between cells of the bone marrow microenvironment.
I also study the function of specific domains within a co-transcriptional activator during megakaryocytopoiesis.
Medical Research Interests
ORCID
0000-0002-5569-6901
Research at a Glance
Yale Co-Authors
Publications Timeline
Diane Krause, MD, PhD
Madeline Mayday
Lin Wang, MS
Betty R. Lawton, PhD
Karin Finberg, MD, PhD
Larissa Lozovatsky
Former YSM
Publications
Featured Publications
Multiparameter analysis of timelapse imaging reveals kinetics of megakaryocytic erythroid progenitor clonal expansion and differentiation
Scanlon VM, Thompson EN, Lawton BR, Kochugaeva M, Ta K, Mayday MY, Xavier-Ferrucio J, Kang E, Eskow NM, Lu YC, Kwon N, Laumas A, Cenci M, Lawrence K, Barden K, Larsuel ST, Reed FE, Peña-Carmona G, Ubbelohde A, Lee JP, Boobalan S, Oppong Y, Anderson R, Maynard C, Sahirul K, Lajeune C, Ivathraya V, Addy T, Sanchez P, Holbrook C, Van Ho AT, Duncan JS, Blau HM, Levchenko A, Krause DS. Multiparameter analysis of timelapse imaging reveals kinetics of megakaryocytic erythroid progenitor clonal expansion and differentiation. Scientific Reports 2022, 12: 16218. PMID: 36171423, PMCID: PMC9519589, DOI: 10.1038/s41598-022-19013-x.Peer-Reviewed Original ResearchCitationsAltmetric
2026
Self-sustaining media-reconstituted GelMA bioink supports printable hematopoietic cultures
Pereira N, Quint J, Mollocana-Lara E, Samandari M, Saeedinejad F, Kutrolli M, Cassells C, Mcewen E, Simon B, Tamayol A, Scanlon V. Self-sustaining media-reconstituted GelMA bioink supports printable hematopoietic cultures. Biomaterials Science 2026, 14: 2701-2717. PMID: 42017530, DOI: 10.1039/d5bm01004g.Peer-Reviewed Original ResearchCitationsSenolytic treatment induces oligodendrocyte dysfunction and demyelination in the corpus callosum
Lombardo E, Pijewski R, Lustig J, Dhari Z, Lahiri A, Papile L, Lavoie E, Scanlon V, Bartley J, Crocker S. Senolytic treatment induces oligodendrocyte dysfunction and demyelination in the corpus callosum. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2524897123. PMID: 41843680, PMCID: PMC13012039, DOI: 10.1073/pnas.2524897123.Peer-Reviewed Original ResearchCitationsAltmetric
2025
Building a transparent and functional laboratory culture: guidelines for creating a Laboratory Handbook for principal investigators
de Bock C, Bridge K, van Gastel N, Gleitz H, Kats L, King K, Machlus K, Psaila B, Scanlon V, Souroullas G, Kokkaliaris K. Building a transparent and functional laboratory culture: guidelines for creating a Laboratory Handbook for principal investigators. Experimental Hematology 2025, 151: 105265. PMID: 40976536, DOI: 10.1016/j.exphem.2025.105265.Peer-Reviewed Original ResearchAltmetricQuantification of intrinsic regulatory factors refines human hematopoietic progenitor definitions and reveals early erythroid lineage priming
Favaro P, Glass D, Borges L, Baskar R, Lam A, Reynolds W, Ho D, Bruce T, Tebaykin D, Koehnke T, Scanlon V, Shestopalov I, Bendall S. Quantification of intrinsic regulatory factors refines human hematopoietic progenitor definitions and reveals early erythroid lineage priming. Cell Reports 2025, 44: 115913. PMID: 40577131, PMCID: PMC13134577, DOI: 10.1016/j.celrep.2025.115913.Peer-Reviewed Original ResearchCitationsAltmetricProteoglycan-4 (PRG4) serum concentration is lower in aged mice, and genetic deficiency impacts survival probability, blood parameters, and bone during aging
Tanguay A, Menon N, Slavin E, Moody M, McEwen E, Jay G, Lorenzo J, Bartley J, Scanlon V, Deymier A, Schmidt T. Proteoglycan-4 (PRG4) serum concentration is lower in aged mice, and genetic deficiency impacts survival probability, blood parameters, and bone during aging. GeroScience 2025, 48: 1371-1384. PMID: 40537697, PMCID: PMC12972433, DOI: 10.1007/s11357-025-01747-x.Peer-Reviewed Original ResearchAltmetric
2023
Assay optimization for the objective quantification of human multilineage colony-forming units
Thompson E, Carlino M, Scanlon V, Grimes H, Krause D. Assay optimization for the objective quantification of human multilineage colony-forming units. Experimental Hematology 2023, 124: 36-44.e3. PMID: 37271449, PMCID: PMC10527702, DOI: 10.1016/j.exphem.2023.05.007.Peer-Reviewed Original ResearchCitationsAltmetricSATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction
Wilkes M, Chae H, Scanlon V, Cepika A, Wentworth E, Saxena M, Eskin A, Chen Z, Glader B, Roncarolo M, Nelson S, Sakamoto K. SATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction. Stem Cells 2023, 41: 560-569. PMID: 36987811, PMCID: PMC10267687, DOI: 10.1093/stmcls/sxad025.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization.
Reed FE, Eskow NM, Min E, Carlino M, Mancuso R, Kwon N, Smith EC, Larsuel ST, Wang L, Scanlon V, Krause DS. Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization. Haematologica 2022 PMID: 36005559.Peer-Reviewed Original ResearchStructure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization
Reed F, Eskow N, Min E, Carlino M, Mancuso R, Kwon N, Smith E, Larsuel S, Wang L, Scanlon V, Krause D. Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization. Haematologica 2022, 107: 2972-2976. PMID: 36453520, PMCID: PMC9713552, DOI: 10.3324/haematol.2021.280499.Peer-Reviewed Original ResearchCitationsAltmetric
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