2014
Exploiting subtle structural differences in heavy‐atom derivatives for experimental phasing
Wang J, Li Y, Modis Y. Exploiting subtle structural differences in heavy‐atom derivatives for experimental phasing. Acta Crystallographica Section D, Structural Biology 2014, 70: 1873-1883. PMID: 25004964, PMCID: PMC4089484, DOI: 10.1107/s1399004714008943.Peer-Reviewed Original ResearchProtein ConformationViral Envelope ProteinsStructural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses
Wang J, Li Y, Modis Y. Structural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses. Virology 2014, 454: 93-101. PMID: 24725935, PMCID: PMC3986810, DOI: 10.1016/j.virol.2014.02.015.Peer-Reviewed Original ResearchMeSH KeywordsGlycoproteinsModels, MolecularPestivirusProtein ConformationProtein MultimerizationViral Envelope Proteins
2013
Crystal structure of glycoprotein E2 from bovine viral diarrhea virus
Li Y, Wang J, Kanai R, Modis Y. Crystal structure of glycoprotein E2 from bovine viral diarrhea virus. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 6805-6810. PMID: 23569276, PMCID: PMC3637714, DOI: 10.1073/pnas.1300524110.Peer-Reviewed Original ResearchConceptsBovine viral diarrhea virus (BVDV) E2C-terminal motifHost cell cytoplasmImportant animal pathogenMembrane fusion mechanismIg-like domainsUnique protein architectureOuter lipid envelopeProtein architectureAnimal pathogensFusion apparatusStructure of E2New foldCellular membranesBovine viral diarrhea virusAromatic residuesViral diarrhea virusCell cytoplasmLipid envelopeDisulfide bondsCell entryDiarrhea virusMajor global health threatCrystal structureFusion mechanism