2022
Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells
Lynall ME, Soskic B, Hayhurst J, Schwartzentruber J, Levey DF, Pathak GA, Polimanti R, Gelernter J, Stein MB, Trynka G, Clatworthy MR, Bullmore E. Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells. Nature Communications 2022, 13: 6102. PMID: 36243721, PMCID: PMC9569335, DOI: 10.1038/s41467-022-33885-7.Peer-Reviewed Original ResearchConceptsMultiple psychiatric disordersPsychiatric disordersPsychiatric risk variantT cellsLymphoid cellsRisk variantsImmune cell subsetsMental health disordersMultiple organ systemsAdaptive immune systemCell subsetsImmune cellsHealth disordersMyeloid cellsImmune systemBrain tissueOrgan systemsSpecific disordersDisordersPathogenesisAbnormalitiesGenetic variantsCellsCD4Variants
2010
Serum proteins and work habits in a group of farm-workers exposed to EBDCs
Polimanti R, Piacentini S, Barone M, Porreca F, Fuciarelli M. Serum proteins and work habits in a group of farm-workers exposed to EBDCs. Annals Of Human Biology 2010, 37: 440-450. PMID: 20377494, DOI: 10.3109/03014461003702195.Peer-Reviewed Original ResearchConceptsUrinary concentrationsLifestyle habitsNon-exposed groupSerum proteinsStudy populationImmunological functionsUrine concentrationsImmune systemIndividual susceptibilityDrug metabolismSerum protein analysisETU levelsPesticide exposureEnvironmental factorsGC polymorphismsPossible linkAssociationExposureSubjectsGenetic componentHabitsPolymorphismGroupEthylenethiourea