Featured Publications
Lower Dopamine D2/3 Receptor Availability is Associated With Worse Verbal Learning and Memory in People Who Smoke Cigarettes
Zakiniaeiz Y, Gueorguieva R, Peltier M, Roberts W, Verplaetse T, Burke C, Morris E, McKee S, Cosgrove K. Lower Dopamine D2/3 Receptor Availability is Associated With Worse Verbal Learning and Memory in People Who Smoke Cigarettes. Nicotine & Tobacco Research 2022, 25: 1047-1051. PMID: 36107715, PMCID: PMC10077933, DOI: 10.1093/ntr/ntac215.Peer-Reviewed Original ResearchConceptsCognitive functionVerbal learningPrefrontal cortexCognitive deficitsWorse verbal learningBrain-behavior relationshipsD2R availabilityDorsolateral prefrontal cortexCognitive performanceComputerized testsTask performanceCogState batteryInhibitory controlNeurocognitive testsReceptor availabilityMesocortical dopaminePositron emission tomographyDopamine D2/3 receptor availabilityMemoryCognitionD2/3 receptor availabilityDopamine releaseSmoking variablesSubject samplesDeficitsSex differences in amphetamine-induced dopamine release in the dorsolateral prefrontal cortex of tobacco smokers
Zakiniaeiz Y, Hillmer AT, Matuskey D, Nabulsi N, Ropchan J, Mazure CM, Picciotto MR, Huang Y, McKee SA, Morris ED, Cosgrove KP. Sex differences in amphetamine-induced dopamine release in the dorsolateral prefrontal cortex of tobacco smokers. Neuropsychopharmacology 2019, 44: 2205-2211. PMID: 31269510, PMCID: PMC6897943, DOI: 10.1038/s41386-019-0456-y.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDA releasePositron emission tomographyD2R availabilityDorsolateral prefrontal cortexMale smokersFemale smokersTobacco smokingPrefrontal cortexAmphetamine-induced DA releaseAmphetamine-induced dopamine releaseCortical DA releaseMesocortical DA systemEffects of nicotineSmoking-related behaviorsMesolimbic dopamine systemLong-term abstinenceSex differencesGender-specific treatmentFemale nonsmokersTobacco smokersAmphetamine administrationDopamine releaseNeurochemical mechanismsNonsmokersSmokers
2021
Neurobiology of Addiction
Gogliettino A, Potenza M, Yip S, Zakiniaeiz Y, Zhai Z. Neurobiology of Addiction. DeckerMed Medical Cannabis 2021 DOI: 10.2310/cannabis.13044.ChaptersFunctional magnetic resonance imagingBrain functionCo-occurring disordersCognitive aspectsGambling disorderBehavioral addictionsCognitive functionAddictive disordersSubstance addictionDSM-5Substance useNegative consequencesNeurochemical systemsNegative healthVisual representationAddictionSocial consequencesExtant literatureNeurobiologyDisordersCurrent treatment strategiesQuality of lifeMagnetic resonance imagingPositron emission tomographyGamblingNeurobiology of Addiction
Gogliettino A, Potenza M, Yip S, Zakiniaeiz Y, Zhai Z. Neurobiology of Addiction. DeckerMed Psychiatry 2021 DOI: 10.2310/psych.13044.ChaptersFunctional magnetic resonance imagingBrain functionCo-occurring disordersCognitive aspectsGambling disorderBehavioral addictionsCognitive functionAddictive disordersSubstance addictionDSM-5Substance useNegative consequencesNeurochemical systemsNegative healthVisual representationAddictionSocial consequencesExtant literatureNeurobiologyDisordersCurrent treatment strategiesQuality of lifeMagnetic resonance imagingPositron emission tomographyGambling