Alterations in Volume and Intrinsic Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder.
Mehta S, Peterson H, Ye J, Ibrahim A, Saeed G, Linsky S, Kreinin I, Tsang S, Nwanaji-Enwerem U, Raso A, Arora J, Tokoglu F, Yip S, Hahn C, Lacadie C, Greene A, Jeon S, Constable R, Barry D, Redeker N, Yaggi H, Scheinost D, Weintraub E. Alterations in Volume and Intrinsic Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder. Radiology 2024, 313: e240514. PMID: 39656127, DOI: 10.1148/radiol.240514.Peer-Reviewed Original ResearchConceptsHealthy control participantsRight medial temporal lobeOpioid use disorderFunctional brain alterationsMedial temporal lobeOpioid use disorder groupFunctional connectivityUse disorderControl participantsBrain alterationsIntrinsic resting-state functional connectivityTemporal lobeMedial prefrontal cortex volumesVoxel-wise linear regressionT1-weighted MRIResting-state functional connectivityFamily-wise error correctionPrefrontal cortex volumeResting-state functional MRIIncreased functional connectivityIntrinsic connectivity distributionFunctional MRI studiesFemale participantsRegional brain volumesAssess group differencesImpact of Sleep Disorders and Disturbed Sleep on Brain Health: A Scientific Statement From the American Heart Association
Gottesman R, Lutsey P, Benveniste H, Brown D, Full K, Lee J, Osorio R, Pase M, Redeker N, Redline S, Spira A, Hypertension O. Impact of Sleep Disorders and Disturbed Sleep on Brain Health: A Scientific Statement From the American Heart Association. Stroke 2024, 55: e61-e76. PMID: 38235581, DOI: 10.1161/str.0000000000000453.Peer-Reviewed Original ResearchConceptsBrain healthSleep disordersDisturbed sleepDevelopment of sleep disordersCognitive outcomesImpact of sleep disordersDevelopment of Alzheimer's diseaseSleep disturbanceBiological basisDisordersBrainSleepAlzheimer's disease-related dementiasAlzheimer's diseaseBenefits of treatmentEarly treatmentScientific statementAmerican Heart AssociationSleep-disordered breathingDementiaAlzheimer